FI883300A0 - Menetelmä uusien terapeuttisesti aktiivisten bentsotiofeenien valmistamiseksi - Google Patents
Menetelmä uusien terapeuttisesti aktiivisten bentsotiofeenien valmistamiseksiInfo
- Publication number
- FI883300A0 FI883300A0 FI883300A FI883300A FI883300A0 FI 883300 A0 FI883300 A0 FI 883300A0 FI 883300 A FI883300 A FI 883300A FI 883300 A FI883300 A FI 883300A FI 883300 A0 FI883300 A0 FI 883300A0
- Authority
- FI
- Finland
- Prior art keywords
- benzothiophenes
- preparation
- therapeutically active
- new therapeutically
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7355487A | 1987-07-14 | 1987-07-14 | |
| US7355487 | 1987-07-14 | ||
| US19169988A | 1988-05-17 | 1988-05-17 | |
| US19169988 | 1988-05-17 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI883300A0 true FI883300A0 (fi) | 1988-07-11 |
| FI883300A FI883300A (fi) | 1989-01-15 |
| FI91256B FI91256B (fi) | 1994-02-28 |
| FI91256C FI91256C (fi) | 1994-06-10 |
Family
ID=26754606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI883300A FI91256C (fi) | 1987-07-14 | 1988-07-11 | Menetelmä uusien terapeuttisesti aktiivisten bentsotiofeenien valmistamiseksi |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0299457B1 (fi) |
| JP (1) | JP2672980B2 (fi) |
| KR (1) | KR970011580B1 (fi) |
| CN (1) | CN1031084A (fi) |
| AT (1) | ATE111908T1 (fi) |
| AU (1) | AU605070B2 (fi) |
| CA (1) | CA1330562C (fi) |
| DE (1) | DE3851584T2 (fi) |
| DK (1) | DK175933B1 (fi) |
| ES (1) | ES2063747T3 (fi) |
| FI (1) | FI91256C (fi) |
| IE (1) | IE64995B1 (fi) |
| NO (1) | NO170886C (fi) |
| NZ (1) | NZ225378A (fi) |
| PH (1) | PH25958A (fi) |
| PT (1) | PT87975B (fi) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2689129B1 (fr) * | 1992-03-27 | 1995-05-12 | Atochem Elf Sa | Nouveaux dérivés de l'acide 3-mercapto-2-thénoique et leurs procédés de préparation. |
| US5426191A (en) * | 1993-12-03 | 1995-06-20 | Warner-Lambert Company | Process for the synthesis of 3-chlorobenzo[b]thiophene-2-carbonyl chlorides |
| US6203803B1 (en) | 1994-12-14 | 2001-03-20 | Societe L'oreal S.A. | Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained |
| FR2719474B1 (fr) | 1994-05-05 | 1996-05-31 | Oreal | Utilisation d'un antagoniste de substance P dans une composition cosmétique et composition obtenue. |
| FR2719476B1 (fr) * | 1994-05-05 | 1997-05-23 | Oreal | Utilisation d'un antagoniste de substance P dans une composition cosmétique et composition obtenue. |
| FR2728166A1 (fr) | 1994-12-19 | 1996-06-21 | Oreal | Composition topique contenant un antagoniste de substance p |
| FR2728793A1 (fr) * | 1994-12-28 | 1996-07-05 | Oreal | Utilisation d'un antagoniste d'histamine, d'un antagoniste d'interleukine 1 et/ou d'un antagoniste de tnf-alpha dans une composition cosmetique, pharmaceutique ou dermatologique et composition obtenue |
| DE19620508A1 (de) * | 1996-05-22 | 1997-11-27 | Hoechst Ag | Schwefelenthaltende heterocyclische Bradykinin-Antagonisten, Verfahren zu ihrer Herstellung und ihre Verwendung |
| MXPA05012953A (es) * | 2003-06-05 | 2006-02-13 | Warner Lambert Co | Benzo[b]tiofenos 3-arilsulfanil y 3-heteroarilsulfanil sustituidos como agentes terapeuticos. |
| US20040259926A1 (en) * | 2003-06-05 | 2004-12-23 | Bruendl Michelle M. | 3-Aryloxy and 3-heteroaryloxy substituted benzo[b]thiophenes as therapeutic agents |
| WO2004108708A1 (en) * | 2003-06-05 | 2004-12-16 | Warner-Lambert Company Llc | 3-substituted indoles and derivatives thereof as therapeutic agents |
| BRPI0410913A (pt) * | 2003-06-05 | 2006-06-27 | Warner Lambert Co | benzotiofenos substituìdos com cicloalquil e heterocicloalquil como agentes terapêuticos |
| DE602004007268D1 (de) * | 2003-06-05 | 2007-08-09 | Warner Lambert Co | CYCLOALKYLSULFANYL-SUBSTITUIERTE BENZOiBöTHIOPHENE ALS THERAPEUTISCHE MITTEL |
| WO2005023800A1 (en) * | 2003-09-04 | 2005-03-17 | Warner-Lambert Company Llc | Halo substituted benzo`b! thiophenes with pi3k inhibitory activity as therapeutic agents |
| FR2862645B1 (fr) * | 2003-11-20 | 2007-06-22 | Merck Sante Sas | Composes antidiabetiques contenant des derives benzofuranes, benzothiophenes |
| US7674822B2 (en) | 2004-11-24 | 2010-03-09 | Wyeth | PTP1b inhibitors |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4140785A (en) * | 1978-05-08 | 1979-02-20 | E. I. Du Pont De Nemours And Company | N-(benzothienopyrazol)amide antirhinoviral agents |
| US4432986A (en) * | 1979-06-18 | 1984-02-21 | Riker Laboratories, Inc. | Tetrazoles bonded to certain polycyclic aromatic systems and anti-allergic use thereof |
| EP0146243A1 (en) * | 1983-10-31 | 1985-06-26 | Merck Frosst Canada Inc. | Lipoxygenase inhibitors |
| GB8401288D0 (en) * | 1984-01-18 | 1984-02-22 | Pfizer Ltd | Therapeutic agents |
| GB8426474D0 (en) * | 1984-10-19 | 1984-11-28 | Ici America Inc | Heterocyclic amides |
| US4675332A (en) * | 1984-12-10 | 1987-06-23 | Warner-Lambert Company | Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents |
| ZA858748B (en) * | 1984-12-10 | 1987-06-24 | Warner Lambert Co | Novel benzothiophenes and benzofurans having antiallergy activity |
| IE58555B1 (en) * | 1984-12-10 | 1993-10-06 | Warner Almbert Company | Novel benzothiophenes and benzofurans having antiallergy activity |
| US4748183A (en) * | 1986-06-13 | 1988-05-31 | Warner-Lambert Company | N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof |
| EP0253650A3 (en) * | 1986-07-18 | 1989-09-13 | Eli Lilly And Company | Improvements relating to benzothiophene derivatives |
-
1988
- 1988-06-21 IE IE187988A patent/IE64995B1/en not_active IP Right Cessation
- 1988-06-30 AU AU18577/88A patent/AU605070B2/en not_active Ceased
- 1988-06-30 CA CA000570900A patent/CA1330562C/en not_active Expired - Fee Related
- 1988-07-11 FI FI883300A patent/FI91256C/fi not_active IP Right Cessation
- 1988-07-12 NZ NZ225378A patent/NZ225378A/en unknown
- 1988-07-12 DK DK198803884A patent/DK175933B1/da not_active IP Right Cessation
- 1988-07-12 NO NO883100A patent/NO170886C/no unknown
- 1988-07-13 PT PT87975A patent/PT87975B/pt not_active IP Right Cessation
- 1988-07-13 AT AT88111224T patent/ATE111908T1/de not_active IP Right Cessation
- 1988-07-13 DE DE3851584T patent/DE3851584T2/de not_active Expired - Fee Related
- 1988-07-13 JP JP63172808A patent/JP2672980B2/ja not_active Expired - Fee Related
- 1988-07-13 ES ES88111224T patent/ES2063747T3/es not_active Expired - Lifetime
- 1988-07-13 EP EP88111224A patent/EP0299457B1/en not_active Expired - Lifetime
- 1988-07-13 PH PH37219A patent/PH25958A/en unknown
- 1988-07-14 CN CN88104422A patent/CN1031084A/zh active Pending
- 1988-07-14 KR KR1019880008717A patent/KR970011580B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0299457A2 (en) | 1989-01-18 |
| FI91256C (fi) | 1994-06-10 |
| KR970011580B1 (ko) | 1997-07-12 |
| AU605070B2 (en) | 1991-01-03 |
| DK388488A (da) | 1989-01-15 |
| FI91256B (fi) | 1994-02-28 |
| PH25958A (en) | 1992-01-13 |
| AU1857788A (en) | 1989-01-19 |
| PT87975B (pt) | 1995-03-01 |
| JP2672980B2 (ja) | 1997-11-05 |
| DK175933B1 (da) | 2005-07-18 |
| IE64995B1 (en) | 1995-09-20 |
| CA1330562C (en) | 1994-07-05 |
| NO170886B (no) | 1992-09-14 |
| DK388488D0 (da) | 1988-07-12 |
| DE3851584D1 (de) | 1994-10-27 |
| NO883100L (no) | 1989-01-16 |
| DE3851584T2 (de) | 1995-01-26 |
| NO170886C (no) | 1992-12-23 |
| ES2063747T3 (es) | 1995-01-16 |
| EP0299457A3 (en) | 1989-07-19 |
| CN1031084A (zh) | 1989-02-15 |
| NZ225378A (en) | 1992-03-26 |
| FI883300A (fi) | 1989-01-15 |
| IE881879L (en) | 1989-01-14 |
| JPH01110682A (ja) | 1989-04-27 |
| ATE111908T1 (de) | 1994-10-15 |
| NO883100D0 (no) | 1988-07-12 |
| KR890002129A (ko) | 1989-04-08 |
| PT87975A (pt) | 1989-06-30 |
| EP0299457B1 (en) | 1994-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| FG | Patent granted |
Owner name: WARNER-LAMBERT COMPANY |
|
| MA | Patent expired |