DE3851584T2 - Gegen Allergie wirkende Benzothiophene und neue und andere ausgewählte Benzothiophene, beide mit Wirkung zur Behandlung von akuten Atmungsangstanzeichen. - Google Patents
Gegen Allergie wirkende Benzothiophene und neue und andere ausgewählte Benzothiophene, beide mit Wirkung zur Behandlung von akuten Atmungsangstanzeichen.Info
- Publication number
- DE3851584T2 DE3851584T2 DE3851584T DE3851584T DE3851584T2 DE 3851584 T2 DE3851584 T2 DE 3851584T2 DE 3851584 T DE3851584 T DE 3851584T DE 3851584 T DE3851584 T DE 3851584T DE 3851584 T2 DE3851584 T2 DE 3851584T2
- Authority
- DE
- Germany
- Prior art keywords
- benzothiophenes
- respiratory distress
- allergic
- effective
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7355487A | 1987-07-14 | 1987-07-14 | |
| US19169988A | 1988-05-17 | 1988-05-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3851584D1 DE3851584D1 (de) | 1994-10-27 |
| DE3851584T2 true DE3851584T2 (de) | 1995-01-26 |
Family
ID=26754606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3851584T Expired - Fee Related DE3851584T2 (de) | 1987-07-14 | 1988-07-13 | Gegen Allergie wirkende Benzothiophene und neue und andere ausgewählte Benzothiophene, beide mit Wirkung zur Behandlung von akuten Atmungsangstanzeichen. |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0299457B1 (de) |
| JP (1) | JP2672980B2 (de) |
| KR (1) | KR970011580B1 (de) |
| CN (1) | CN1031084A (de) |
| AT (1) | ATE111908T1 (de) |
| AU (1) | AU605070B2 (de) |
| CA (1) | CA1330562C (de) |
| DE (1) | DE3851584T2 (de) |
| DK (1) | DK175933B1 (de) |
| ES (1) | ES2063747T3 (de) |
| FI (1) | FI91256C (de) |
| IE (1) | IE64995B1 (de) |
| NO (1) | NO170886C (de) |
| NZ (1) | NZ225378A (de) |
| PH (1) | PH25958A (de) |
| PT (1) | PT87975B (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2689129B1 (fr) * | 1992-03-27 | 1995-05-12 | Atochem Elf Sa | Nouveaux dérivés de l'acide 3-mercapto-2-thénoique et leurs procédés de préparation. |
| US5426191A (en) * | 1993-12-03 | 1995-06-20 | Warner-Lambert Company | Process for the synthesis of 3-chlorobenzo[b]thiophene-2-carbonyl chlorides |
| FR2719474B1 (fr) | 1994-05-05 | 1996-05-31 | Oreal | Utilisation d'un antagoniste de substance P dans une composition cosmétique et composition obtenue. |
| US6203803B1 (en) | 1994-12-14 | 2001-03-20 | Societe L'oreal S.A. | Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained |
| FR2719476B1 (fr) * | 1994-05-05 | 1997-05-23 | Oreal | Utilisation d'un antagoniste de substance P dans une composition cosmétique et composition obtenue. |
| FR2728166A1 (fr) | 1994-12-19 | 1996-06-21 | Oreal | Composition topique contenant un antagoniste de substance p |
| FR2728793A1 (fr) | 1994-12-28 | 1996-07-05 | Oreal | Utilisation d'un antagoniste d'histamine, d'un antagoniste d'interleukine 1 et/ou d'un antagoniste de tnf-alpha dans une composition cosmetique, pharmaceutique ou dermatologique et composition obtenue |
| DE19620508A1 (de) * | 1996-05-22 | 1997-11-27 | Hoechst Ag | Schwefelenthaltende heterocyclische Bradykinin-Antagonisten, Verfahren zu ihrer Herstellung und ihre Verwendung |
| US20040259926A1 (en) * | 2003-06-05 | 2004-12-23 | Bruendl Michelle M. | 3-Aryloxy and 3-heteroaryloxy substituted benzo[b]thiophenes as therapeutic agents |
| BRPI0410940A (pt) * | 2003-06-05 | 2006-08-29 | Warner Lambert Co | benzo[b]tiofenos substituìdos com cicloalquilsulfanila como agentes terapêuticos |
| EP1644360A1 (de) * | 2003-06-05 | 2006-04-12 | Warner-Lambert Company LLC | 3-substituierte indole und ihre derivate als therapeutische mittel |
| CA2527573A1 (en) * | 2003-06-05 | 2004-12-16 | Warner-Lambert Company Llc | Cycloalkyl and heterocycloalkyl substituted benzothiophenes as therapeutic agents |
| WO2004108716A1 (en) * | 2003-06-05 | 2004-12-16 | Warner-Lambert Company Llc | 3-arylsulfanyl and 3-heteroarylsulfanyl substituted benzo[b]thiophenes as therapeutic agents |
| WO2005023800A1 (en) * | 2003-09-04 | 2005-03-17 | Warner-Lambert Company Llc | Halo substituted benzo`b! thiophenes with pi3k inhibitory activity as therapeutic agents |
| FR2862645B1 (fr) * | 2003-11-20 | 2007-06-22 | Merck Sante Sas | Composes antidiabetiques contenant des derives benzofuranes, benzothiophenes |
| US7674822B2 (en) | 2004-11-24 | 2010-03-09 | Wyeth | PTP1b inhibitors |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4140785A (en) * | 1978-05-08 | 1979-02-20 | E. I. Du Pont De Nemours And Company | N-(benzothienopyrazol)amide antirhinoviral agents |
| US4432986A (en) * | 1979-06-18 | 1984-02-21 | Riker Laboratories, Inc. | Tetrazoles bonded to certain polycyclic aromatic systems and anti-allergic use thereof |
| EP0146243A1 (de) * | 1983-10-31 | 1985-06-26 | Merck Frosst Canada Inc. | Lipoxygenase-Inhibitoren |
| GB8401288D0 (en) * | 1984-01-18 | 1984-02-22 | Pfizer Ltd | Therapeutic agents |
| GB8426474D0 (en) * | 1984-10-19 | 1984-11-28 | Ici America Inc | Heterocyclic amides |
| ZA858748B (en) * | 1984-12-10 | 1987-06-24 | Warner Lambert Co | Novel benzothiophenes and benzofurans having antiallergy activity |
| IE58555B1 (en) * | 1984-12-10 | 1993-10-06 | Warner Almbert Company | Novel benzothiophenes and benzofurans having antiallergy activity |
| US4675332A (en) * | 1984-12-10 | 1987-06-23 | Warner-Lambert Company | Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents |
| US4748183A (en) * | 1986-06-13 | 1988-05-31 | Warner-Lambert Company | N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof |
| EP0253650A3 (de) * | 1986-07-18 | 1989-09-13 | Eli Lilly And Company | Benzothiophen-Derivate |
-
1988
- 1988-06-21 IE IE187988A patent/IE64995B1/en not_active IP Right Cessation
- 1988-06-30 AU AU18577/88A patent/AU605070B2/en not_active Ceased
- 1988-06-30 CA CA000570900A patent/CA1330562C/en not_active Expired - Fee Related
- 1988-07-11 FI FI883300A patent/FI91256C/fi not_active IP Right Cessation
- 1988-07-12 DK DK198803884A patent/DK175933B1/da not_active IP Right Cessation
- 1988-07-12 NZ NZ225378A patent/NZ225378A/en unknown
- 1988-07-12 NO NO883100A patent/NO170886C/no unknown
- 1988-07-13 ES ES88111224T patent/ES2063747T3/es not_active Expired - Lifetime
- 1988-07-13 PT PT87975A patent/PT87975B/pt not_active IP Right Cessation
- 1988-07-13 JP JP63172808A patent/JP2672980B2/ja not_active Expired - Fee Related
- 1988-07-13 EP EP88111224A patent/EP0299457B1/de not_active Expired - Lifetime
- 1988-07-13 PH PH37219A patent/PH25958A/en unknown
- 1988-07-13 AT AT88111224T patent/ATE111908T1/de not_active IP Right Cessation
- 1988-07-13 DE DE3851584T patent/DE3851584T2/de not_active Expired - Fee Related
- 1988-07-14 KR KR1019880008717A patent/KR970011580B1/ko not_active IP Right Cessation
- 1988-07-14 CN CN88104422A patent/CN1031084A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA1330562C (en) | 1994-07-05 |
| EP0299457B1 (de) | 1994-09-21 |
| FI883300A (fi) | 1989-01-15 |
| PT87975B (pt) | 1995-03-01 |
| NO170886B (no) | 1992-09-14 |
| EP0299457A2 (de) | 1989-01-18 |
| FI91256C (fi) | 1994-06-10 |
| DK388488D0 (da) | 1988-07-12 |
| NO883100L (no) | 1989-01-16 |
| KR970011580B1 (ko) | 1997-07-12 |
| NO883100D0 (no) | 1988-07-12 |
| CN1031084A (zh) | 1989-02-15 |
| AU1857788A (en) | 1989-01-19 |
| NZ225378A (en) | 1992-03-26 |
| ES2063747T3 (es) | 1995-01-16 |
| FI883300A0 (fi) | 1988-07-11 |
| PH25958A (en) | 1992-01-13 |
| PT87975A (pt) | 1989-06-30 |
| DE3851584D1 (de) | 1994-10-27 |
| JPH01110682A (ja) | 1989-04-27 |
| FI91256B (fi) | 1994-02-28 |
| KR890002129A (ko) | 1989-04-08 |
| AU605070B2 (en) | 1991-01-03 |
| EP0299457A3 (en) | 1989-07-19 |
| IE881879L (en) | 1989-01-14 |
| NO170886C (no) | 1992-12-23 |
| DK175933B1 (da) | 2005-07-18 |
| JP2672980B2 (ja) | 1997-11-05 |
| IE64995B1 (en) | 1995-09-20 |
| DK388488A (da) | 1989-01-15 |
| ATE111908T1 (de) | 1994-10-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3851584D1 (de) | Gegen Allergie wirkende Benzothiophene und neue und andere ausgewählte Benzothiophene, beide mit Wirkung zur Behandlung von akuten Atmungsangstanzeichen. | |
| DE69212326D1 (de) | Azeotropische zusammensetzungen von 1,1,1,2,3,4,4,5,5,5 decafluoropentan und trans-1,2-dichlorethylen, cis-1,2-dichlorethylen oder 1,1-dichlorethan | |
| DE3884622D1 (de) | Schmiermittelzubereitung zur behandlung von rheuma. | |
| DE69528475T2 (de) | Verwendung von serotonin-antagonisten (5ht3) zur behandlung von fibromyalgie | |
| DE69018457D1 (de) | Gegenstände zur behandlung von periodontitis und knochendefekten. | |
| DE69019488T2 (de) | Behandlung von Geflügel. | |
| DE3878627D1 (de) | Zusammensetzung zur oberflaechenbehandlung von kautschuk. | |
| DE3878417T2 (de) | Einrichtung zum teilen von geschlachtetem gefluegel und zum zeitlichen unterbrechen des transportes der karkassen oder teile. | |
| DE69429299T2 (de) | Verwendung von Tachykinin-Antagonisten zur Behandlung von Erbrechen | |
| DE69018043T2 (de) | Behandlung von Geflügel. | |
| DE3869590D1 (de) | Mischung zur behandlung von hypercholesterolemie. | |
| DE3850433D1 (de) | Allergiebehandlung und Zusammensetzung dafür. | |
| DE68911776D1 (de) | Konjugierte Oxybutenolide zur Behandlung von Ulcera. | |
| DE69002558D1 (de) | Zusammensetzungen und methoden zur verhinderung von inkrustierungen. | |
| ATE25969T1 (de) | 1,7-diphenyl-3-methylaza-7-cyan-8-methyl-nonan zur verwendung bei der bekaempfung von krankheiten. | |
| DE68907569D1 (de) | Mittel zur behandlung oder vorbeugung von aids. | |
| DE3586420D1 (de) | Verwendung von dihydropyridinen zur behandlung und praevention von arteriosklerose. | |
| DE69000960D1 (de) | Zusammensetzung zur behandlung von pigmentierung. | |
| DE69022027T2 (de) | 2-Alkyl-3-benzoylbenzofurane zur Behandlung von Herzarrhythmia. | |
| DE3882023D1 (de) | Am aromatischen kern und an der seitenkette fluoratome enthaltende alkoxyaniline und verfahren zur herstellung von am aromatischen kern und an der seitenkette fluoratome enthaltenden alkoxyanilinen. | |
| DE3881377D1 (de) | Mittel zur prophylaxe und behandlung von thrombocytopenie. | |
| DE69011565D1 (de) | Herstellung von Pre-Kaseinaten und Verwendung. | |
| DE68916814D1 (de) | Mittel zur behandlung von pediculosis capitis. | |
| ATE108321T1 (de) | Mittel zur behandlung von pediculosis capitis. | |
| DE58902466D1 (de) | Acyl-carnitin zur behandlung und zur verhuetung von virusinfektionen. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |