DK172192B1 - Nye benzothiazepinderivater, fremgangsmåder til fremstilling deraf og farmaceutiske præparater - Google Patents

Nye benzothiazepinderivater, fremgangsmåder til fremstilling deraf og farmaceutiske præparater Download PDF

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Publication number
DK172192B1
DK172192B1 DK283984A DK283984A DK172192B1 DK 172192 B1 DK172192 B1 DK 172192B1 DK 283984 A DK283984 A DK 283984A DK 283984 A DK283984 A DK 283984A DK 172192 B1 DK172192 B1 DK 172192B1
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DK
Denmark
Prior art keywords
ethyl
cis
chloro
mixture
dihydro
Prior art date
Application number
DK283984A
Other languages
Danish (da)
English (en)
Other versions
DK283984D0 (da
DK283984A (da
Inventor
Tokuro Oh-Ishi
Mikio Takeda
Hiromichi Nakajima
Taku Nagao
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of DK283984D0 publication Critical patent/DK283984D0/da
Publication of DK283984A publication Critical patent/DK283984A/da
Application granted granted Critical
Publication of DK172192B1 publication Critical patent/DK172192B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • C07D281/04Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK283984A 1983-06-11 1984-06-08 Nye benzothiazepinderivater, fremgangsmåder til fremstilling deraf og farmaceutiske præparater DK172192B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8316032 1983-06-11
GB838316032A GB8316032D0 (en) 1983-06-11 1983-06-11 Benzothiazepine derivatives

Publications (3)

Publication Number Publication Date
DK283984D0 DK283984D0 (da) 1984-06-08
DK283984A DK283984A (da) 1984-12-12
DK172192B1 true DK172192B1 (da) 1997-12-22

Family

ID=10544142

Family Applications (1)

Application Number Title Priority Date Filing Date
DK283984A DK172192B1 (da) 1983-06-11 1984-06-08 Nye benzothiazepinderivater, fremgangsmåder til fremstilling deraf og farmaceutiske præparater

Country Status (13)

Country Link
US (1) US4521430A (ko)
EP (1) EP0128462B1 (ko)
JP (1) JPS59231076A (ko)
KR (1) KR890000019B1 (ko)
AT (1) ATE41659T1 (ko)
AU (1) AU563094B2 (ko)
CA (1) CA1218651A (ko)
DE (1) DE3477380D1 (ko)
DK (1) DK172192B1 (ko)
ES (2) ES8604185A1 (ko)
GB (1) GB8316032D0 (ko)
HK (1) HK1491A (ko)
SG (1) SG54490G (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4585768A (en) * 1984-04-10 1986-04-29 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivatives and processes for preparing the same
IL71538A (en) * 1984-04-13 1987-07-31 Abic Ltd Process for the preparation of benzothiazepine derivatives
USRE33072E (en) * 1985-06-20 1989-09-26 E. R. Squibb & Sons, Inc. Benzothiazepine derivatives
US4584131A (en) * 1985-06-20 1986-04-22 E. R. Squibb & Sons, Inc. Benzothiazepine derivatives
JPS649981A (en) * 1987-06-29 1989-01-13 Tanabe Seiyaku Co 1,5-benzothiazepine derivative
US4912102A (en) * 1988-02-01 1990-03-27 Hoffmann-La Roche Inc. Analogs of naphtho[1,2-β] [1,4] thiazepin-4(5H)-one
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
FR2638745B1 (fr) * 1988-11-08 1994-01-14 Synthelabo Derives de ((n-alkylthioalkyl-methylamino)-2 ethyl)-5 benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique
ATE155689T1 (de) * 1991-01-10 1997-08-15 Amylin Pharmaceuticals Inc Aktivätsmessungen des amylin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1236467A (en) * 1967-10-28 1971-06-23 Tanabe Seiyaku Co Benzothiazepine derivatives
DE1923568A1 (de) * 1969-05-08 1970-11-12 Squibb & Sons Inc Benzothiazepine,ihre Salze mit Saeuren und quartaeren Ammoniumsalze
JPS5899471A (ja) * 1981-12-07 1983-06-13 Tanabe Seiyaku Co Ltd ベンゾチアゼピン誘導体の新規製造法

Also Published As

Publication number Publication date
AU563094B2 (en) 1987-06-25
ATE41659T1 (de) 1989-04-15
EP0128462A1 (en) 1984-12-19
ES533282A0 (es) 1986-01-16
ES8604185A1 (es) 1986-01-16
DK283984D0 (da) 1984-06-08
ES8702390A1 (es) 1986-12-16
EP0128462B1 (en) 1989-03-22
ES548196A0 (es) 1986-12-16
KR850000421A (ko) 1985-02-27
KR890000019B1 (ko) 1989-03-06
CA1218651A (en) 1987-03-03
JPH0374221B2 (ko) 1991-11-26
JPS59231076A (ja) 1984-12-25
GB8316032D0 (en) 1983-07-13
DK283984A (da) 1984-12-12
AU2887584A (en) 1984-12-13
US4521430A (en) 1985-06-04
SG54490G (en) 1990-09-07
DE3477380D1 (en) 1989-04-27
HK1491A (en) 1991-01-11

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
B1 Patent granted (law 1993)
PBP Patent lapsed