DE3477380D1 - Novel benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions - Google Patents

Novel benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions

Info

Publication number
DE3477380D1
DE3477380D1 DE8484106188T DE3477380T DE3477380D1 DE 3477380 D1 DE3477380 D1 DE 3477380D1 DE 8484106188 T DE8484106188 T DE 8484106188T DE 3477380 T DE3477380 T DE 3477380T DE 3477380 D1 DE3477380 D1 DE 3477380D1
Authority
DE
Germany
Prior art keywords
processes
pharmaceutical compositions
preparing
lower alkyl
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484106188T
Other languages
English (en)
Inventor
Tokuro Oh-Ishi
Mikio Takeda
Hiromichi Nakajima
Taku Nagao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Application granted granted Critical
Publication of DE3477380D1 publication Critical patent/DE3477380D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DE8484106188T 1983-06-11 1984-05-30 Novel benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions Expired DE3477380D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838316032A GB8316032D0 (en) 1983-06-11 1983-06-11 Benzothiazepine derivatives

Publications (1)

Publication Number Publication Date
DE3477380D1 true DE3477380D1 (en) 1989-04-27

Family

ID=10544142

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484106188T Expired DE3477380D1 (en) 1983-06-11 1984-05-30 Novel benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions

Country Status (13)

Country Link
US (1) US4521430A (de)
EP (1) EP0128462B1 (de)
JP (1) JPS59231076A (de)
KR (1) KR890000019B1 (de)
AT (1) ATE41659T1 (de)
AU (1) AU563094B2 (de)
CA (1) CA1218651A (de)
DE (1) DE3477380D1 (de)
DK (1) DK172192B1 (de)
ES (2) ES8604185A1 (de)
GB (1) GB8316032D0 (de)
HK (1) HK1491A (de)
SG (1) SG54490G (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4585768A (en) * 1984-04-10 1986-04-29 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivatives and processes for preparing the same
IL71538A (en) * 1984-04-13 1987-07-31 Abic Ltd Process for the preparation of benzothiazepine derivatives
US4584131A (en) * 1985-06-20 1986-04-22 E. R. Squibb & Sons, Inc. Benzothiazepine derivatives
USRE33072E (en) * 1985-06-20 1989-09-26 E. R. Squibb & Sons, Inc. Benzothiazepine derivatives
JPS649981A (en) * 1987-06-29 1989-01-13 Tanabe Seiyaku Co 1,5-benzothiazepine derivative
US4912102A (en) * 1988-02-01 1990-03-27 Hoffmann-La Roche Inc. Analogs of naphtho[1,2-β] [1,4] thiazepin-4(5H)-one
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
FR2638745B1 (fr) * 1988-11-08 1994-01-14 Synthelabo Derives de ((n-alkylthioalkyl-methylamino)-2 ethyl)-5 benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique
JP2818296B2 (ja) * 1991-01-10 1998-10-30 アミリン・ファーマシューティカルズ・インコーポレイテッド アミリン活性検定

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1236467A (en) * 1967-10-28 1971-06-23 Tanabe Seiyaku Co Benzothiazepine derivatives
DE1923568A1 (de) * 1969-05-08 1970-11-12 Squibb & Sons Inc Benzothiazepine,ihre Salze mit Saeuren und quartaeren Ammoniumsalze
JPS5899471A (ja) * 1981-12-07 1983-06-13 Tanabe Seiyaku Co Ltd ベンゾチアゼピン誘導体の新規製造法

Also Published As

Publication number Publication date
SG54490G (en) 1990-09-07
CA1218651A (en) 1987-03-03
HK1491A (en) 1991-01-11
EP0128462A1 (de) 1984-12-19
EP0128462B1 (de) 1989-03-22
DK283984D0 (da) 1984-06-08
ES533282A0 (es) 1986-01-16
US4521430A (en) 1985-06-04
JPS59231076A (ja) 1984-12-25
DK172192B1 (da) 1997-12-22
KR890000019B1 (ko) 1989-03-06
KR850000421A (ko) 1985-02-27
JPH0374221B2 (de) 1991-11-26
ES548196A0 (es) 1986-12-16
GB8316032D0 (en) 1983-07-13
AU563094B2 (en) 1987-06-25
DK283984A (da) 1984-12-12
ES8604185A1 (es) 1986-01-16
AU2887584A (en) 1984-12-13
ES8702390A1 (es) 1986-12-16
ATE41659T1 (de) 1989-04-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee