DK171237B1 - Adenosinderivater, deres fremstilling, farmaceutiske midler med indhold deraf og anvendelse deraf til fremstilling af farmaceutiske midler - Google Patents
Adenosinderivater, deres fremstilling, farmaceutiske midler med indhold deraf og anvendelse deraf til fremstilling af farmaceutiske midler Download PDFInfo
- Publication number
- DK171237B1 DK171237B1 DK473289A DK473289A DK171237B1 DK 171237 B1 DK171237 B1 DK 171237B1 DK 473289 A DK473289 A DK 473289A DK 473289 A DK473289 A DK 473289A DK 171237 B1 DK171237 B1 DK 171237B1
- Authority
- DK
- Denmark
- Prior art keywords
- adenosine
- derivative
- chloro
- compound
- methylidene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24991188A | 1988-09-27 | 1988-09-27 | |
| US24991188 | 1988-09-27 | ||
| US38939189A | 1989-08-03 | 1989-08-03 | |
| US38939189 | 1989-08-03 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK473289D0 DK473289D0 (da) | 1989-09-26 |
| DK473289A DK473289A (da) | 1990-03-28 |
| DK171237B1 true DK171237B1 (da) | 1996-08-05 |
Family
ID=26940460
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK473289A DK171237B1 (da) | 1988-09-27 | 1989-09-26 | Adenosinderivater, deres fremstilling, farmaceutiske midler med indhold deraf og anvendelse deraf til fremstilling af farmaceutiske midler |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0365849B1 (no) |
| JP (1) | JP2968002B2 (no) |
| KR (1) | KR0146333B1 (no) |
| CN (1) | CN1046334A (no) |
| AR (1) | AR248283A1 (no) |
| AT (1) | ATE111477T1 (no) |
| AU (1) | AU621664B2 (no) |
| CA (1) | CA1336903C (no) |
| DE (1) | DE68918215T2 (no) |
| DK (1) | DK171237B1 (no) |
| ES (1) | ES2063796T3 (no) |
| FI (1) | FI94763C (no) |
| HU (1) | HU204843B (no) |
| IE (1) | IE63561B1 (no) |
| IL (1) | IL91773A (no) |
| NO (1) | NO171857C (no) |
| NZ (1) | NZ230766A (no) |
| PT (1) | PT91803B (no) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5206244A (en) * | 1990-10-18 | 1993-04-27 | E. R. Squibb & Sons, Inc. | Hydroxymethyl (methylenecyclopentyl) purines and pyrimidines |
| US5340816A (en) * | 1990-10-18 | 1994-08-23 | E. R. Squibb & Sons, Inc. | Hydroxymethyl(methylenecyclopentyl) purines and pyrimidines |
| FR2668153B1 (fr) * | 1990-10-22 | 1995-03-31 | Pasteur Merieux Serums Vacc | Nouveaux composes ribonucleosides, leur procede de preparation et les medicaments les contenant. |
| AU662630B2 (en) * | 1992-05-12 | 1995-09-07 | Aventis Inc. | A process for the preparation of ribonucleotide reductase inhibitors |
| US5589587A (en) * | 1992-05-12 | 1996-12-31 | Merrell Pharmaceuticals Inc. | Process for the preparation of ribonucleotide reductase inhibitors |
| US5627053A (en) * | 1994-03-29 | 1997-05-06 | Ribozyme Pharmaceuticals, Inc. | 2'deoxy-2'-alkylnucleotide containing nucleic acid |
| US5811408A (en) * | 1994-07-12 | 1998-09-22 | Yamasa Corporation | 2'-deoxy-2'-(substituted or unsubstituted)methylidene-4'-thionucleosides |
| DE60024257T2 (de) * | 1999-06-09 | 2006-07-20 | Anticancer Inc., San Diego | Modulatoren der methylierung zur kontrolle von bakterieller virulenz |
| US6579857B1 (en) | 1999-06-11 | 2003-06-17 | Evanston Northwestern Healthcare Research Institute | Combination cancer therapy comprising adenosine and deaminase enzyme inhibitors |
| BR0307712A (pt) * | 2002-02-14 | 2005-05-24 | Pharmasset Ltd | Composto, composição e uso dos mesmos no tratamento de infecções por flaviviridae e proliferação celular anormal |
| EP2794627B1 (en) | 2011-12-22 | 2018-09-26 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| USRE48171E1 (en) | 2012-03-21 | 2020-08-25 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0267878A1 (en) * | 1986-11-14 | 1988-05-18 | Ciba-Geigy Ag | N9-cyclopentyl-substituted adenine derivatives |
| WO1988007049A1 (en) * | 1987-03-19 | 1988-09-22 | Yamasa Shoyu Kabushiki Kaisha | 2'-alkylidenepyrimidine nucleoside derivatives, process for their preparation, and their use |
| NZ225906A (en) * | 1987-08-26 | 1990-10-26 | Merrell Dow Pharma | Aristeromycin/adenosine derivatives and pharmaceutical compositions |
| ZA894534B (en) * | 1988-06-20 | 1990-03-28 | Merrell Dow Pharma | Novel neplanocin derivatives |
-
1989
- 1989-09-22 HU HU894982A patent/HU204843B/hu not_active IP Right Cessation
- 1989-09-25 NZ NZ230766A patent/NZ230766A/en unknown
- 1989-09-25 IL IL9177389A patent/IL91773A/en not_active IP Right Cessation
- 1989-09-26 NO NO893826A patent/NO171857C/no not_active IP Right Cessation
- 1989-09-26 IE IE308089A patent/IE63561B1/en not_active IP Right Cessation
- 1989-09-26 KR KR1019890013825A patent/KR0146333B1/ko not_active IP Right Cessation
- 1989-09-26 JP JP1250413A patent/JP2968002B2/ja not_active Expired - Fee Related
- 1989-09-26 FI FI894546A patent/FI94763C/fi not_active IP Right Cessation
- 1989-09-26 EP EP89117735A patent/EP0365849B1/en not_active Expired - Lifetime
- 1989-09-26 ES ES89117735T patent/ES2063796T3/es not_active Expired - Lifetime
- 1989-09-26 DE DE68918215T patent/DE68918215T2/de not_active Expired - Fee Related
- 1989-09-26 CN CN89108169A patent/CN1046334A/zh active Pending
- 1989-09-26 AR AR89315002A patent/AR248283A1/es active
- 1989-09-26 AU AU41760/89A patent/AU621664B2/en not_active Ceased
- 1989-09-26 DK DK473289A patent/DK171237B1/da not_active IP Right Cessation
- 1989-09-26 AT AT89117735T patent/ATE111477T1/de not_active IP Right Cessation
- 1989-09-26 PT PT91803A patent/PT91803B/pt not_active IP Right Cessation
- 1989-09-27 CA CA000613429A patent/CA1336903C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO171857C (no) | 1993-05-12 |
| AU621664B2 (en) | 1992-03-19 |
| AU4176089A (en) | 1990-04-05 |
| NO171857B (no) | 1993-02-01 |
| FI94763B (fi) | 1995-07-14 |
| FI894546A (fi) | 1990-03-28 |
| NO893826D0 (no) | 1989-09-26 |
| EP0365849B1 (en) | 1994-09-14 |
| DK473289A (da) | 1990-03-28 |
| PT91803A (pt) | 1990-03-30 |
| DE68918215T2 (de) | 1995-02-02 |
| PT91803B (pt) | 1995-05-31 |
| JP2968002B2 (ja) | 1999-10-25 |
| JPH02160769A (ja) | 1990-06-20 |
| FI894546A0 (fi) | 1989-09-26 |
| HU204843B (en) | 1992-02-28 |
| DE68918215D1 (de) | 1994-10-20 |
| IL91773A (en) | 1994-02-27 |
| AR248283A1 (es) | 1995-07-12 |
| ATE111477T1 (de) | 1994-09-15 |
| HUT50844A (en) | 1990-03-28 |
| EP0365849A3 (en) | 1990-12-27 |
| KR900004736A (ko) | 1990-04-12 |
| FI94763C (fi) | 1995-10-25 |
| IL91773A0 (en) | 1990-06-10 |
| IE893080L (en) | 1990-03-27 |
| CA1336903C (en) | 1995-09-05 |
| KR0146333B1 (ko) | 1998-08-01 |
| IE63561B1 (en) | 1995-05-17 |
| DK473289D0 (da) | 1989-09-26 |
| NO893826L (no) | 1990-03-28 |
| CN1046334A (zh) | 1990-10-24 |
| ES2063796T3 (es) | 1995-01-16 |
| EP0365849A2 (en) | 1990-05-02 |
| NZ230766A (en) | 1992-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |
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