DK170100B1 - 2'-Substituerede 4-deoxytiazolo(5,4-c)rifamycin SV-derivater, fremgangsmåde til fremstilling heraf, en sådan forbindelse til anvendelse som lægemiddel, anvendelse af forbindelsen til fremstilling af et antibakterielt medikament samt farmaceutisk præparat indeholdende forbindelsen - Google Patents

2'-Substituerede 4-deoxytiazolo(5,4-c)rifamycin SV-derivater, fremgangsmåde til fremstilling heraf, en sådan forbindelse til anvendelse som lægemiddel, anvendelse af forbindelsen til fremstilling af et antibakterielt medikament samt farmaceutisk præparat indeholdende forbindelsen Download PDF

Info

Publication number
DK170100B1
DK170100B1 DK630686A DK630686A DK170100B1 DK 170100 B1 DK170100 B1 DK 170100B1 DK 630686 A DK630686 A DK 630686A DK 630686 A DK630686 A DK 630686A DK 170100 B1 DK170100 B1 DK 170100B1
Authority
DK
Denmark
Prior art keywords
compound
rifamycin
alkyl
group
optionally substituted
Prior art date
Application number
DK630686A
Other languages
Danish (da)
English (en)
Other versions
DK630686D0 (da
DK630686A (da
Inventor
Bruno Cavalleri
Marco Turconi
Giovanni Tamborini
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of DK630686D0 publication Critical patent/DK630686D0/da
Publication of DK630686A publication Critical patent/DK630686A/da
Application granted granted Critical
Publication of DK170100B1 publication Critical patent/DK170100B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK630686A 1985-12-30 1986-12-29 2'-Substituerede 4-deoxytiazolo(5,4-c)rifamycin SV-derivater, fremgangsmåde til fremstilling heraf, en sådan forbindelse til anvendelse som lægemiddel, anvendelse af forbindelsen til fremstilling af et antibakterielt medikament samt farmaceutisk præparat indeholdende forbindelsen DK170100B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858531887A GB8531887D0 (en) 1985-12-30 1985-12-30 Rifamycin sv derivatives
GB8531887 1985-12-30

Publications (3)

Publication Number Publication Date
DK630686D0 DK630686D0 (da) 1986-12-29
DK630686A DK630686A (da) 1987-07-01
DK170100B1 true DK170100B1 (da) 1995-05-22

Family

ID=10590333

Family Applications (1)

Application Number Title Priority Date Filing Date
DK630686A DK170100B1 (da) 1985-12-30 1986-12-29 2'-Substituerede 4-deoxytiazolo(5,4-c)rifamycin SV-derivater, fremgangsmåde til fremstilling heraf, en sådan forbindelse til anvendelse som lægemiddel, anvendelse af forbindelsen til fremstilling af et antibakterielt medikament samt farmaceutisk præparat indeholdende forbindelsen

Country Status (17)

Country Link
US (1) US4880789A (ja)
EP (1) EP0228606B1 (ja)
JP (1) JPH07108909B2 (ja)
KR (1) KR940009795B1 (ja)
AT (1) ATE60772T1 (ja)
CA (1) CA1271472A (ja)
DE (1) DE3677485D1 (ja)
DK (1) DK170100B1 (ja)
ES (1) ES2031815T3 (ja)
GB (1) GB8531887D0 (ja)
GR (1) GR3001543T3 (ja)
HK (1) HK97391A (ja)
HU (1) HU196812B (ja)
IE (1) IE59505B1 (ja)
IL (1) IL80447A (ja)
SG (1) SG67091G (ja)
ZA (1) ZA869453B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0497125T3 (da) * 1991-01-28 1999-08-16 Lepetit Spa Fremgangsmåde til fremstilling af 2'-(diethylamino)rifamycin P (P/DEA)
US6375658B1 (en) 2000-04-28 2002-04-23 Smith & Nephew, Inc. Cartilage grafting
US7265107B2 (en) 2004-03-10 2007-09-04 Cumbre Pharmaceuticals Inc. Rifamycin C-11 oxime cyclo derivatives effective against drug-resistant microbes
US7256187B2 (en) 2004-03-10 2007-08-14 Cumbre Pharmaceuticals Inc. Rifamycin C-11 oxime derivatives effective against drug-resistant microbes
US20100125146A1 (en) * 2008-11-19 2010-05-20 Johnson Matthey Public Limited Company Method for making pharmaceutical compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1470426A (en) * 1974-08-30 1977-04-14 Lepetit Spa Rifamycins
GB1523198A (en) * 1976-05-28 1978-08-31 Lepetit Spa Thiazolo-rifamycin derivatives
GB1523199A (en) * 1976-05-28 1978-08-31 Lepetit Spa Rifamycin sv derivatives
CH629212A5 (it) * 1976-10-18 1982-04-15 Erba Farmitalia Procedimento per la preparazione di composti di rifamicina.
GB1594134A (en) * 1977-11-25 1981-07-30 Holco Investment Inc Rifamycins
IT1111173B (it) * 1978-04-27 1986-01-13 Lepetit Spa Derivati rifamicinici
FI812936L (fi) * 1980-09-25 1982-03-26 Ciba Geigy Ag Nya 2-aminoimidazoler foerfaranden foer deras framstaellning dessa foereningar innehaollande farmaceutiska preparat och deras anvaendning

Also Published As

Publication number Publication date
JPH07108909B2 (ja) 1995-11-22
HUT45072A (en) 1988-05-30
IE59505B1 (en) 1994-03-09
IL80447A0 (en) 1987-01-30
IL80447A (en) 1990-09-17
ZA869453B (en) 1987-09-30
DK630686D0 (da) 1986-12-29
US4880789A (en) 1989-11-14
ATE60772T1 (de) 1991-02-15
ES2031815T3 (es) 1993-01-01
GR3001543T3 (en) 1992-11-23
GB8531887D0 (en) 1986-02-05
CA1271472A (en) 1990-07-10
JPS62158292A (ja) 1987-07-14
IE863277L (en) 1987-06-30
KR940009795B1 (ko) 1994-10-17
EP0228606A3 (en) 1989-01-11
HU196812B (en) 1989-01-30
EP0228606A2 (en) 1987-07-15
DK630686A (da) 1987-07-01
DE3677485D1 (de) 1991-03-14
SG67091G (en) 1991-09-13
EP0228606B1 (en) 1991-02-06
KR870006057A (ko) 1987-07-09
HK97391A (en) 1991-12-13

Similar Documents

Publication Publication Date Title
EP0366914B1 (en) 3'-Hydroxybenzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same
SU724087A3 (ru) Способ получени гидрохлорида оптически активных дауносаминилпроизводных антрациклинонов
DK149062B (da) Analogifremgangsmaade til fremstilling af cefuroximestere
SU1586521A3 (ru) Способ получени производных гликопептидов
EP0313874B1 (en) Disulfur analogs of LL-E33288 antitumor agents
DK170100B1 (da) 2'-Substituerede 4-deoxytiazolo(5,4-c)rifamycin SV-derivater, fremgangsmåde til fremstilling heraf, en sådan forbindelse til anvendelse som lægemiddel, anvendelse af forbindelsen til fremstilling af et antibakterielt medikament samt farmaceutisk præparat indeholdende forbindelsen
JPS5896097A (ja) エリスロマイシンｂ誘導体
ZA200300472B (en) Process for the preparation of highly pure crystalline (R,S)-cefuroxime axetil.
EP0333176B1 (en) Substituted benzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same
DE69314072T2 (de) Cephalosporin-Derivat
AT390956B (de) Verfahren zur herstellung von neuen, in 3-stellung substituierten propenylaminothiazolylcephalosporansaeuren und deren estern
EP1828206B1 (en) Process for the preparation of cefixime
US4322412A (en) Anthracycline glycosides, their preparation, use and compositions thereof
US4929612A (en) Thiadiazolylacetamide cephem derivatives
HUT74883A (en) New process and intermediates for preparing naphthyridonecarboxylic acid salts
EP0004270B1 (en) Streptovaricin c derivatives, a process for their preparation and antiviral compositions containing them
FI69079C (fi) Foerfarande foer framstaellning av rifamycinderivat med antibakterisk aktivitet
CN110437177A (zh) 一种截短侧耳素衍生物及其制备方法和用途
KR950010086B1 (ko) 신규 2'-치환-4-데옥시-티아졸로[5,4-c]리파마이신 SV 유도체
JP2544488B2 (ja) ３’―ヒドロキシベンゾキサジノリファマイシン誘導体
CN111662351B (zh) 新奥克梯隆型皂苷元衍生物及制备抗耐药菌药物应用
JPH02188597A (ja) 新抗生物質ｎ―アセチルベナノマイシンｂならびにその製造法
US4545936A (en) Novel aminonaphthacene derivatives and process for preparation thereof
JPH01242589A (ja) セフエム化合物
GB1572993A (en) Ester derivatives of cefuroxime

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed