ATE60772T1 - 2'-substituierte 4-deoxythiazolo(5,4-c>rifamycin- sv-derivate. - Google Patents
2'-substituierte 4-deoxythiazolo(5,4-c>rifamycin- sv-derivate.Info
- Publication number
- ATE60772T1 ATE60772T1 AT86117005T AT86117005T ATE60772T1 AT E60772 T1 ATE60772 T1 AT E60772T1 AT 86117005 T AT86117005 T AT 86117005T AT 86117005 T AT86117005 T AT 86117005T AT E60772 T1 ATE60772 T1 AT E60772T1
- Authority
- AT
- Austria
- Prior art keywords
- rifamycin
- derivatives
- substituted
- deoxythiazolo
- thiazolo
- Prior art date
Links
- HJYYPODYNSCCOU-ODRIEIDWSA-N rifamycin SV Chemical class OC1=C(C(O)=C2C)C3=C(O)C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O HJYYPODYNSCCOU-ODRIEIDWSA-N 0.000 title abstract 3
- HJYYPODYNSCCOU-ZDHWWVNNSA-N Rifamycin SV Natural products COC1C=COC2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(=O)C)C1C)C)cc(O)c4c3C2=O HJYYPODYNSCCOU-ZDHWWVNNSA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 238000007385 chemical modification Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940109171 rifamycin sv Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858531887A GB8531887D0 (en) | 1985-12-30 | 1985-12-30 | Rifamycin sv derivatives |
| EP19860117005 EP0228606B1 (de) | 1985-12-30 | 1986-12-06 | 2'-Substituierte 4-Deoxythiazolo[5,4-c]rifamycin-SV-Derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE60772T1 true ATE60772T1 (de) | 1991-02-15 |
Family
ID=10590333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86117005T ATE60772T1 (de) | 1985-12-30 | 1986-12-06 | 2'-substituierte 4-deoxythiazolo(5,4-c>rifamycin- sv-derivate. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4880789A (de) |
| EP (1) | EP0228606B1 (de) |
| JP (1) | JPH07108909B2 (de) |
| KR (1) | KR940009795B1 (de) |
| AT (1) | ATE60772T1 (de) |
| CA (1) | CA1271472A (de) |
| DE (1) | DE3677485D1 (de) |
| DK (1) | DK170100B1 (de) |
| ES (1) | ES2031815T3 (de) |
| GB (1) | GB8531887D0 (de) |
| GR (1) | GR3001543T3 (de) |
| HK (1) | HK97391A (de) |
| HU (1) | HU196812B (de) |
| IE (1) | IE59505B1 (de) |
| IL (1) | IL80447A (de) |
| SG (1) | SG67091G (de) |
| ZA (1) | ZA869453B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE174336T1 (de) * | 1991-01-28 | 1998-12-15 | Lepetit Spa | Verfahren zur herstellung von 2'- diethylaminorifamycin p (p/dea) |
| US6375658B1 (en) | 2000-04-28 | 2002-04-23 | Smith & Nephew, Inc. | Cartilage grafting |
| US7256187B2 (en) | 2004-03-10 | 2007-08-14 | Cumbre Pharmaceuticals Inc. | Rifamycin C-11 oxime derivatives effective against drug-resistant microbes |
| US7265107B2 (en) | 2004-03-10 | 2007-09-04 | Cumbre Pharmaceuticals Inc. | Rifamycin C-11 oxime cyclo derivatives effective against drug-resistant microbes |
| US20100125146A1 (en) * | 2008-11-19 | 2010-05-20 | Johnson Matthey Public Limited Company | Method for making pharmaceutical compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1470426A (en) * | 1974-08-30 | 1977-04-14 | Lepetit Spa | Rifamycins |
| GB1523199A (en) * | 1976-05-28 | 1978-08-31 | Lepetit Spa | Rifamycin sv derivatives |
| GB1523198A (en) * | 1976-05-28 | 1978-08-31 | Lepetit Spa | Thiazolo-rifamycin derivatives |
| CH629212A5 (it) * | 1976-10-18 | 1982-04-15 | Erba Farmitalia | Procedimento per la preparazione di composti di rifamicina. |
| GB1594134A (en) * | 1977-11-25 | 1981-07-30 | Holco Investment Inc | Rifamycins |
| IT1111173B (it) * | 1978-04-27 | 1986-01-13 | Lepetit Spa | Derivati rifamicinici |
| FI812936L (fi) * | 1980-09-25 | 1982-03-26 | Ciba Geigy Ag | Nya 2-aminoimidazoler foerfaranden foer deras framstaellning dessa foereningar innehaollande farmaceutiska preparat och deras anvaendning |
-
1985
- 1985-12-30 GB GB858531887A patent/GB8531887D0/en active Pending
-
1986
- 1986-10-29 IL IL80447A patent/IL80447A/xx not_active IP Right Cessation
- 1986-12-06 ES ES198686117005T patent/ES2031815T3/es not_active Expired - Lifetime
- 1986-12-06 DE DE8686117005T patent/DE3677485D1/de not_active Expired - Lifetime
- 1986-12-06 AT AT86117005T patent/ATE60772T1/de not_active IP Right Cessation
- 1986-12-06 EP EP19860117005 patent/EP0228606B1/de not_active Expired - Lifetime
- 1986-12-16 IE IE327786A patent/IE59505B1/en not_active IP Right Cessation
- 1986-12-17 ZA ZA869453A patent/ZA869453B/xx unknown
- 1986-12-18 KR KR1019860010871A patent/KR940009795B1/ko not_active Expired - Fee Related
- 1986-12-25 JP JP61308066A patent/JPH07108909B2/ja not_active Expired - Lifetime
- 1986-12-29 HU HU865501A patent/HU196812B/hu not_active IP Right Cessation
- 1986-12-29 CA CA000526359A patent/CA1271472A/en not_active Expired - Lifetime
- 1986-12-29 DK DK630686A patent/DK170100B1/da not_active IP Right Cessation
-
1988
- 1988-08-24 US US07/238,985 patent/US4880789A/en not_active Expired - Fee Related
-
1991
- 1991-03-04 GR GR91400257T patent/GR3001543T3/el unknown
- 1991-08-16 SG SG670/91A patent/SG67091G/en unknown
- 1991-12-05 HK HK973/91A patent/HK97391A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2031815T3 (es) | 1993-01-01 |
| HK97391A (en) | 1991-12-13 |
| GB8531887D0 (en) | 1986-02-05 |
| DK630686A (da) | 1987-07-01 |
| EP0228606B1 (de) | 1991-02-06 |
| GR3001543T3 (en) | 1992-11-23 |
| KR870006057A (ko) | 1987-07-09 |
| DK170100B1 (da) | 1995-05-22 |
| IE863277L (en) | 1987-06-30 |
| HUT45072A (en) | 1988-05-30 |
| SG67091G (en) | 1991-09-13 |
| CA1271472A (en) | 1990-07-10 |
| JPS62158292A (ja) | 1987-07-14 |
| DK630686D0 (da) | 1986-12-29 |
| ZA869453B (en) | 1987-09-30 |
| IL80447A0 (en) | 1987-01-30 |
| EP0228606A2 (de) | 1987-07-15 |
| KR940009795B1 (ko) | 1994-10-17 |
| JPH07108909B2 (ja) | 1995-11-22 |
| HU196812B (en) | 1989-01-30 |
| IL80447A (en) | 1990-09-17 |
| US4880789A (en) | 1989-11-14 |
| EP0228606A3 (en) | 1989-01-11 |
| DE3677485D1 (de) | 1991-03-14 |
| IE59505B1 (en) | 1994-03-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |