DK170099B1 - t-Butyl-ergolin-derivativer, fremgangsmåde til fremstilling deraf, samt farmaceutiske præparater indeholdende disse - Google Patents
t-Butyl-ergolin-derivativer, fremgangsmåde til fremstilling deraf, samt farmaceutiske præparater indeholdende disse Download PDFInfo
- Publication number
- DK170099B1 DK170099B1 DK322587A DK322587A DK170099B1 DK 170099 B1 DK170099 B1 DK 170099B1 DK 322587 A DK322587 A DK 322587A DK 322587 A DK322587 A DK 322587A DK 170099 B1 DK170099 B1 DK 170099B1
- Authority
- DK
- Denmark
- Prior art keywords
- ergoline
- butyl
- formula
- methyl
- hydrogen atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Liquid Developers In Electrophotography (AREA)
- Graft Or Block Polymers (AREA)
- Developing Agents For Electrophotography (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868615471A GB8615471D0 (en) | 1986-06-25 | 1986-06-25 | T-butyl ergoline derivatives |
GB8615471 | 1986-06-25 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK322587D0 DK322587D0 (da) | 1987-06-24 |
DK322587A DK322587A (da) | 1987-12-26 |
DK170099B1 true DK170099B1 (da) | 1995-05-22 |
Family
ID=10600059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK322587A DK170099B1 (da) | 1986-06-25 | 1987-06-24 | t-Butyl-ergolin-derivativer, fremgangsmåde til fremstilling deraf, samt farmaceutiske præparater indeholdende disse |
Country Status (20)
Country | Link |
---|---|
US (2) | US4843073A (fi) |
EP (1) | EP0251652B1 (fi) |
JP (1) | JPH0745498B2 (fi) |
KR (1) | KR950008970B1 (fi) |
AT (1) | ATE76407T1 (fi) |
AU (1) | AU597672B2 (fi) |
CA (1) | CA1339533C (fi) |
DE (1) | DE3779190D1 (fi) |
DK (1) | DK170099B1 (fi) |
ES (1) | ES2042567T3 (fi) |
FI (1) | FI85702C (fi) |
GB (1) | GB8615471D0 (fi) |
GR (1) | GR3005115T3 (fi) |
HU (1) | HU196201B (fi) |
IE (1) | IE61319B1 (fi) |
IL (1) | IL82946A (fi) |
NZ (1) | NZ220543A (fi) |
PT (1) | PT85152B (fi) |
SU (1) | SU1547708A3 (fi) |
ZA (1) | ZA874569B (fi) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61245164A (ja) * | 1985-04-23 | 1986-10-31 | Seiko Instr & Electronics Ltd | パタ−ン修正装置 |
HU193782B (en) * | 1985-06-21 | 1987-11-30 | Richter Gedeon Vegyeszet | Process for producing 2-halogeno-nicergoline derivatives and acid additional salts thereof |
US6060483A (en) * | 1996-06-27 | 2000-05-09 | Pharmacia & Upjohn S.P.A. | Antineurodegenerative ergoline derivatives |
WO2014195849A2 (en) * | 2013-06-03 | 2014-12-11 | Mahesh Kandula | Compositions and methods for the treatment of cerebrovascular diseases |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3228945A (en) * | 1966-01-11 | Methyl and i,g-dimethyl-b-(a-hydroxy- alkyl)-ergoline i derivatives | ||
US3228941A (en) * | 1966-01-11 | Methyl and i,g-dimethyl-ergoline i derivatives | ||
US3228942A (en) * | 1966-01-11 | Methyl and i,g-dimeti-iyl ergoline i compounds | ||
DE203721C (fi) * | 1908-05-05 | |||
US3232942A (en) * | 1964-06-02 | 1966-02-01 | Sandoz Ltd | 1-substituted (+)-lysergol |
US3879554A (en) * | 1970-03-20 | 1975-04-22 | Farmaceutici Italia | Use of 1,6-dimethyl-8-{62 -(5-bromonicotinoyloxymethyl)-10 {60 -methoxyergoline in treating cerebral and peripheral metabolic vascular disorders |
USRE30218E (en) * | 1974-12-06 | 1980-02-19 | Eli Lilly And Company | 8,8-Disubstituted-6-methylergolines and related compounds |
US3959288A (en) * | 1974-12-13 | 1976-05-25 | Eli Lilly And Company | 8-Oxymethylergolines and process therefor |
US4199579A (en) * | 1975-03-14 | 1980-04-22 | Siphar S. A. | Carbamates of 2-haloergolines and 2-haloergolenes and process for the preparation thereof |
DE2656344A1 (de) * | 1975-12-23 | 1977-07-07 | Sandoz Ag | Ergolinderivate, ihre verwendung und herstellung |
IT1192260B (it) * | 1977-07-05 | 1988-03-31 | Simes | Derivati di ergoline-2-tioeteri e loro solfossidi |
GB2056437A (en) * | 1979-08-07 | 1981-03-18 | Erba Farmitalia | Secoergoline derivatives |
US4382940A (en) * | 1979-12-06 | 1983-05-10 | Farmitalia Carlo Erba S.P.A. | Ercoline derivatives and therapeutic compositions having CNS affecting activity |
DE3403067A1 (de) * | 1984-01-30 | 1985-08-14 | Eckart Prof. Dr. 6500 Mainz Eich | Ergolin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung |
IT1213206B (it) * | 1984-08-07 | 1989-12-14 | Inverni Della Beffa Spa | Procedimento per la preparazione di derivati del lisergolo. |
GB8612366D0 (en) * | 1986-05-21 | 1986-06-25 | Erba Farmitalia | Ergoline esters |
AU7914587A (en) * | 1987-08-24 | 1989-03-31 | Molecular Control Corporation | Liquid crystal micelles, display, having concentric spheres |
-
1986
- 1986-06-25 GB GB868615471A patent/GB8615471D0/en active Pending
-
1987
- 1987-06-03 NZ NZ220543A patent/NZ220543A/xx unknown
- 1987-06-22 FI FI872752A patent/FI85702C/fi not_active IP Right Cessation
- 1987-06-22 IL IL82946A patent/IL82946A/xx not_active IP Right Cessation
- 1987-06-22 IE IE165287A patent/IE61319B1/en not_active IP Right Cessation
- 1987-06-22 JP JP62155265A patent/JPH0745498B2/ja not_active Expired - Lifetime
- 1987-06-23 CA CA000540338A patent/CA1339533C/en not_active Expired - Fee Related
- 1987-06-23 AU AU74632/87A patent/AU597672B2/en not_active Ceased
- 1987-06-23 AT AT87305570T patent/ATE76407T1/de not_active IP Right Cessation
- 1987-06-23 EP EP87305570A patent/EP0251652B1/en not_active Expired - Lifetime
- 1987-06-23 ES ES87305570T patent/ES2042567T3/es not_active Expired - Lifetime
- 1987-06-23 DE DE8787305570T patent/DE3779190D1/de not_active Expired - Fee Related
- 1987-06-23 PT PT85152A patent/PT85152B/pt not_active IP Right Cessation
- 1987-06-23 KR KR1019870006362A patent/KR950008970B1/ko not_active IP Right Cessation
- 1987-06-23 US US07/065,597 patent/US4843073A/en not_active Expired - Fee Related
- 1987-06-24 HU HU872871A patent/HU196201B/hu not_active IP Right Cessation
- 1987-06-24 SU SU874202786A patent/SU1547708A3/ru active
- 1987-06-24 DK DK322587A patent/DK170099B1/da not_active IP Right Cessation
- 1987-06-24 ZA ZA874569A patent/ZA874569B/xx unknown
-
1989
- 1989-03-24 US US07/328,518 patent/US5079364A/en not_active Expired - Fee Related
-
1992
- 1992-07-08 GR GR920401458T patent/GR3005115T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
KR880000429A (ko) | 1988-03-25 |
ZA874569B (en) | 1988-02-24 |
JPH0745498B2 (ja) | 1995-05-17 |
PT85152B (pt) | 1990-03-30 |
KR950008970B1 (ko) | 1995-08-10 |
US4843073A (en) | 1989-06-27 |
PT85152A (en) | 1987-07-01 |
IL82946A0 (en) | 1987-12-20 |
AU7463287A (en) | 1988-01-07 |
ES2042567T3 (es) | 1993-12-16 |
HU196201B (en) | 1988-10-28 |
EP0251652A2 (en) | 1988-01-07 |
FI872752A0 (fi) | 1987-06-22 |
GR3005115T3 (fi) | 1993-05-24 |
AU597672B2 (en) | 1990-06-07 |
US5079364A (en) | 1992-01-07 |
CA1339533C (en) | 1997-11-11 |
IE871652L (en) | 1987-12-25 |
EP0251652A3 (en) | 1989-04-05 |
IL82946A (en) | 1991-04-15 |
JPS6322577A (ja) | 1988-01-30 |
DK322587A (da) | 1987-12-26 |
DE3779190D1 (de) | 1992-06-25 |
FI872752A (fi) | 1987-12-26 |
ATE76407T1 (de) | 1992-06-15 |
IE61319B1 (en) | 1994-11-02 |
FI85702B (fi) | 1992-02-14 |
NZ220543A (en) | 1989-06-28 |
SU1547708A3 (ru) | 1990-02-28 |
FI85702C (fi) | 1992-05-25 |
EP0251652B1 (en) | 1992-05-20 |
HUT44543A (en) | 1988-03-28 |
DK322587D0 (da) | 1987-06-24 |
GB8615471D0 (en) | 1986-07-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4277476A (en) | Derivatives of fluorenes and fluoranthenes and process for their preparation | |
EP0030351B1 (en) | Ergoline derivatives, their preparation and therapeutic composition containing them | |
DK170099B1 (da) | t-Butyl-ergolin-derivativer, fremgangsmåde til fremstilling deraf, samt farmaceutiske præparater indeholdende disse | |
US4634708A (en) | Indolophenanthridines useful as dopaminergic and analgesic agents | |
JP3466527B2 (ja) | 新規なアコニチン系化合物および鎮痛・抗炎症剤 | |
IE49920B1 (en) | Vincaminic acid derivatives and process for their preparation | |
US3563990A (en) | 1-substituted-4-aryl-2(1h)-quinazolinones | |
US3962262A (en) | 1,8-naphthyridine compounds | |
US3917833A (en) | Amino-substituted benzocycloheptenones for inducing sleep | |
US3324133A (en) | 2-nitrogen 6-methyl and 1, 6-dimethylergoline derivatives | |
FR2531709A1 (fr) | Diazabicyclooctanes, procede pour leur preparation et compositions pharmaceutiques les renfermant | |
US3280145A (en) | New indole derivatives and their acid addition salts | |
EP0015786B1 (fr) | Imidazo et pyrimido-pyrido-indoles, leur préparation et médicaments les contenant | |
US4031103A (en) | 1,8-Naphthyridine compounds | |
US3585201A (en) | 10-alkoxy 9,10-dihydro ergoline derivatives | |
US3657270A (en) | 1-phenyl-1h-indazole-4-acetic acids | |
US3576004A (en) | Novel ring-e substituted 4-cyano-3-secoyohimbanes | |
AU638874B2 (en) | Ergoline derivatives useful as dopamine antagonistic agents | |
US3373166A (en) | Novel 17-[(methylthio)methoxy] yohimbanes | |
EP0043811A1 (fr) | Nouvelles indolonaphtyridines et leur utilisation en tant que médicaments | |
EP0012347A1 (de) | 7,8,9,10-Tetrahydrothieno(3,2-e)pyrido(4,3-b)indole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel | |
HU182754B (en) | Process for preparing tetrahydro-2h-benzo/c/pyrrole derivatives | |
EP0014792B1 (en) | Tetrahydro-2h-benzo(c)pyrroles, their preparation, pharmaceutical compositions containing them and the compounds for use as therapeuticals | |
JPS54132583A (en) | Preparation of 3-isoquinolone derivative | |
BE886513A (fr) | Derives de l'ergoline, procede pour les preparer et leur emploi comme medicaments |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |