DK170043B1 - 5-phenyl-1,4,5,6-tetrahydropyrimidinderivater, fremgangsmåde til fremstilling heraf, farmaceutisk middel indeholdende disse samt anvendelse af derivaterne til fremstilling af et farmaceutisk middel - Google Patents

5-phenyl-1,4,5,6-tetrahydropyrimidinderivater, fremgangsmåde til fremstilling heraf, farmaceutisk middel indeholdende disse samt anvendelse af derivaterne til fremstilling af et farmaceutisk middel Download PDF

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Publication number
DK170043B1
DK170043B1 DK601386A DK601386A DK170043B1 DK 170043 B1 DK170043 B1 DK 170043B1 DK 601386 A DK601386 A DK 601386A DK 601386 A DK601386 A DK 601386A DK 170043 B1 DK170043 B1 DK 170043B1
Authority
DK
Denmark
Prior art keywords
crl
dose
mice
phenyl
tetrahydropyrimidine
Prior art date
Application number
DK601386A
Other languages
Danish (da)
English (en)
Other versions
DK601386A (da
DK601386D0 (da
Inventor
Louis Lafon
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8518462A external-priority patent/FR2591592B1/fr
Priority claimed from FR8603644A external-priority patent/FR2595696B2/fr
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of DK601386D0 publication Critical patent/DK601386D0/da
Publication of DK601386A publication Critical patent/DK601386A/da
Application granted granted Critical
Publication of DK170043B1 publication Critical patent/DK170043B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/04—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
DK601386A 1985-12-13 1986-12-12 5-phenyl-1,4,5,6-tetrahydropyrimidinderivater, fremgangsmåde til fremstilling heraf, farmaceutisk middel indeholdende disse samt anvendelse af derivaterne til fremstilling af et farmaceutisk middel DK170043B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8518462 1985-12-13
FR8518462A FR2591592B1 (fr) 1985-12-13 1985-12-13 Derives de 5-phenyl-1,4,5,6-tetrahydropyrimidine, procede de preparation et utilisation en therapeutique
FR8603644 1986-03-14
FR8603644A FR2595696B2 (fr) 1986-03-14 1986-03-14 Derives de 5-phenyl-1, 4, 5, 6-tetrahydropyrimidine, procede de preparation et utilisation en therapeutique

Publications (3)

Publication Number Publication Date
DK601386D0 DK601386D0 (da) 1986-12-12
DK601386A DK601386A (da) 1987-06-14
DK170043B1 true DK170043B1 (da) 1995-05-08

Family

ID=26224881

Family Applications (1)

Application Number Title Priority Date Filing Date
DK601386A DK170043B1 (da) 1985-12-13 1986-12-12 5-phenyl-1,4,5,6-tetrahydropyrimidinderivater, fremgangsmåde til fremstilling heraf, farmaceutisk middel indeholdende disse samt anvendelse af derivaterne til fremstilling af et farmaceutisk middel

Country Status (11)

Country Link
US (1) US4774248A (de)
EP (1) EP0226511B1 (de)
JP (1) JPH0764827B2 (de)
AU (1) AU585105B2 (de)
CA (1) CA1273016A (de)
DE (1) DE3664768D1 (de)
DK (1) DK170043B1 (de)
ES (1) ES2010668B3 (de)
GR (1) GR3000200T3 (de)
IE (1) IE59330B1 (de)
PT (1) PT83922B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2536947Y2 (ja) * 1990-03-27 1997-05-28 日本電気株式会社 電歪効果素子
ZA9610738B (en) * 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
TW427978B (en) * 1996-02-03 2001-04-01 Hoffmann La Roche Tetrahydroisoquinoline derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001232A (en) * 1974-08-17 1977-01-04 Bayer Aktiengesellschaft Process for preparing 1-substituted 2-methyl-tetrahydropyrimidines
FI753673A (de) * 1975-01-15 1976-07-16 Merck & Co Inc
DE2751805A1 (de) * 1977-11-19 1979-05-23 Veba Chemie Ag Verfahren zur herstellung von blockierten polyisocyanaten
US4281126A (en) * 1978-01-30 1981-07-28 Petrolite Corporation N-Substituted 1,2,3,4-tetrahydropyrimidines, Hexahydropyrimidines and process for their preparation
DE3041834A1 (de) * 1980-11-06 1982-06-09 Bayer Ag, 5090 Leverkusen Neue amidine und amidin/isocyanat-addukte, verfahren zu ihrer herstellung und ihre verwendung als katalysatoren fuer die haertung von epoxidharzen
US4404302A (en) * 1982-05-27 1983-09-13 Ferro Corporation Acylated hindered hexahydropyrimidines and their use as light stabilizing agents

Also Published As

Publication number Publication date
AU585105B2 (en) 1989-06-08
ES2010668B3 (es) 1989-12-01
DE3664768D1 (en) 1989-09-07
GR3000200T3 (en) 1990-12-31
CA1273016A (en) 1990-08-21
PT83922A (fr) 1987-01-01
US4774248A (en) 1988-09-27
PT83922B (pt) 1989-06-30
JPS62187460A (ja) 1987-08-15
DK601386A (da) 1987-06-14
EP0226511A1 (de) 1987-06-24
AU6639586A (en) 1987-06-18
JPH0764827B2 (ja) 1995-07-12
EP0226511B1 (de) 1989-08-02
IE863254L (en) 1987-06-13
DK601386D0 (da) 1986-12-12
IE59330B1 (en) 1994-02-09

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed