DE3664768D1 - 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives, preparation process and medicinal use - Google Patents

5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives, preparation process and medicinal use

Info

Publication number
DE3664768D1
DE3664768D1 DE8686402703T DE3664768T DE3664768D1 DE 3664768 D1 DE3664768 D1 DE 3664768D1 DE 8686402703 T DE8686402703 T DE 8686402703T DE 3664768 T DE3664768 T DE 3664768T DE 3664768 D1 DE3664768 D1 DE 3664768D1
Authority
DE
Germany
Prior art keywords
phenyl
preparation process
medicinal use
tetrahydropyrimidine derivatives
tetrahydropyrimidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8686402703T
Other languages
English (en)
Inventor
Louis Lafon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8518462A external-priority patent/FR2591592B1/fr
Priority claimed from FR8603644A external-priority patent/FR2595696B2/fr
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Application granted granted Critical
Publication of DE3664768D1 publication Critical patent/DE3664768D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/04—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8686402703T 1985-12-13 1986-12-05 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives, preparation process and medicinal use Expired DE3664768D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8518462A FR2591592B1 (fr) 1985-12-13 1985-12-13 Derives de 5-phenyl-1,4,5,6-tetrahydropyrimidine, procede de preparation et utilisation en therapeutique
FR8603644A FR2595696B2 (fr) 1986-03-14 1986-03-14 Derives de 5-phenyl-1, 4, 5, 6-tetrahydropyrimidine, procede de preparation et utilisation en therapeutique

Publications (1)

Publication Number Publication Date
DE3664768D1 true DE3664768D1 (en) 1989-09-07

Family

ID=26224881

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686402703T Expired DE3664768D1 (en) 1985-12-13 1986-12-05 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives, preparation process and medicinal use

Country Status (11)

Country Link
US (1) US4774248A (de)
EP (1) EP0226511B1 (de)
JP (1) JPH0764827B2 (de)
AU (1) AU585105B2 (de)
CA (1) CA1273016A (de)
DE (1) DE3664768D1 (de)
DK (1) DK170043B1 (de)
ES (1) ES2010668B3 (de)
GR (1) GR3000200T3 (de)
IE (1) IE59330B1 (de)
PT (1) PT83922B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2536947Y2 (ja) * 1990-03-27 1997-05-28 日本電気株式会社 電歪効果素子
ZA9610738B (en) * 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
TW427978B (en) * 1996-02-03 2001-04-01 Hoffmann La Roche Tetrahydroisoquinoline derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001232A (en) * 1974-08-17 1977-01-04 Bayer Aktiengesellschaft Process for preparing 1-substituted 2-methyl-tetrahydropyrimidines
FI753673A (de) * 1975-01-15 1976-07-16 Merck & Co Inc
DE2751805A1 (de) * 1977-11-19 1979-05-23 Veba Chemie Ag Verfahren zur herstellung von blockierten polyisocyanaten
US4281126A (en) * 1978-01-30 1981-07-28 Petrolite Corporation N-Substituted 1,2,3,4-tetrahydropyrimidines, Hexahydropyrimidines and process for their preparation
DE3041834A1 (de) * 1980-11-06 1982-06-09 Bayer Ag, 5090 Leverkusen Neue amidine und amidin/isocyanat-addukte, verfahren zu ihrer herstellung und ihre verwendung als katalysatoren fuer die haertung von epoxidharzen
US4404302A (en) * 1982-05-27 1983-09-13 Ferro Corporation Acylated hindered hexahydropyrimidines and their use as light stabilizing agents

Also Published As

Publication number Publication date
GR3000200T3 (en) 1990-12-31
AU585105B2 (en) 1989-06-08
EP0226511A1 (de) 1987-06-24
IE863254L (en) 1987-06-13
JPS62187460A (ja) 1987-08-15
AU6639586A (en) 1987-06-18
IE59330B1 (en) 1994-02-09
US4774248A (en) 1988-09-27
PT83922A (fr) 1987-01-01
EP0226511B1 (de) 1989-08-02
ES2010668B3 (es) 1989-12-01
DK170043B1 (da) 1995-05-08
CA1273016A (en) 1990-08-21
PT83922B (pt) 1989-06-30
DK601386D0 (da) 1986-12-12
JPH0764827B2 (ja) 1995-07-12
DK601386A (da) 1987-06-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee