DK169818B1 - Ergolinderivater, fremgangsmåde til fremstilling deraf, samt farmaceutisk præparat indeholdende disse - Google Patents
Ergolinderivater, fremgangsmåde til fremstilling deraf, samt farmaceutisk præparat indeholdende disse Download PDFInfo
- Publication number
- DK169818B1 DK169818B1 DK254687A DK254687A DK169818B1 DK 169818 B1 DK169818 B1 DK 169818B1 DK 254687 A DK254687 A DK 254687A DK 254687 A DK254687 A DK 254687A DK 169818 B1 DK169818 B1 DK 169818B1
- Authority
- DK
- Denmark
- Prior art keywords
- methyl
- pharmaceutically acceptable
- ergoline
- reduction
- represents hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8612366 | 1986-05-21 | ||
| GB868612366A GB8612366D0 (en) | 1986-05-21 | 1986-05-21 | Ergoline esters |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK254687D0 DK254687D0 (da) | 1987-05-19 |
| DK254687A DK254687A (da) | 1987-11-22 |
| DK169818B1 true DK169818B1 (da) | 1995-03-06 |
Family
ID=10598207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK254687A DK169818B1 (da) | 1986-05-21 | 1987-05-19 | Ergolinderivater, fremgangsmåde til fremstilling deraf, samt farmaceutisk præparat indeholdende disse |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4785001A (ko) |
| EP (1) | EP0249761B1 (ko) |
| JP (1) | JPH0723375B2 (ko) |
| KR (1) | KR950006866B1 (ko) |
| AT (1) | ATE82287T1 (ko) |
| AU (1) | AU588109B2 (ko) |
| CA (1) | CA1292224C (ko) |
| DE (1) | DE3782548T2 (ko) |
| DK (1) | DK169818B1 (ko) |
| ES (1) | ES2052512T3 (ko) |
| FI (1) | FI85142C (ko) |
| GB (1) | GB8612366D0 (ko) |
| GR (1) | GR3006298T3 (ko) |
| HU (1) | HU196069B (ko) |
| IE (1) | IE60655B1 (ko) |
| IL (1) | IL82556A (ko) |
| NZ (1) | NZ220341A (ko) |
| PT (1) | PT84897B (ko) |
| SU (1) | SU1549482A3 (ko) |
| ZA (1) | ZA873592B (ko) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU193782B (en) * | 1985-06-21 | 1987-11-30 | Richter Gedeon Vegyeszet | Process for producing 2-halogeno-nicergoline derivatives and acid additional salts thereof |
| GB8615471D0 (en) * | 1986-06-25 | 1986-07-30 | Erba Farmitalia | T-butyl ergoline derivatives |
| ATE204278T1 (de) * | 1992-12-24 | 2001-09-15 | Pharmacia & Upjohn Spa | Serotoninergische ergolin derivate |
| GB9407637D0 (en) | 1994-04-18 | 1994-06-08 | Erba Carlo Spa | Serotoninergic abeo-ergoline derivatives |
| GB9603226D0 (en) * | 1996-02-15 | 1996-04-17 | Pharmacia Spa | Heterocyclyl-ergoline derivatives |
| US6060483A (en) * | 1996-06-27 | 2000-05-09 | Pharmacia & Upjohn S.P.A. | Antineurodegenerative ergoline derivatives |
| DE10018834A1 (de) * | 2000-04-15 | 2001-10-25 | Lohmann Therapie Syst Lts | Transdermale oder transmucosale Darreichungsformen mit einer nicotinhaltigen Wirkstoffkombination zur Raucherentwöhnung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3879554A (en) * | 1970-03-20 | 1975-04-22 | Farmaceutici Italia | Use of 1,6-dimethyl-8-{62 -(5-bromonicotinoyloxymethyl)-10 {60 -methoxyergoline in treating cerebral and peripheral metabolic vascular disorders |
| FR2189046B1 (ko) * | 1972-06-22 | 1978-07-28 | Farmaceutici Italia | |
| US4057635A (en) * | 1973-05-23 | 1977-11-08 | Simes Societa Italiana Medicinali E Sintetici S.P.A. | Carbamates of ergolines and therapeutic compositions therewith |
| US4199579A (en) * | 1975-03-14 | 1980-04-22 | Siphar S. A. | Carbamates of 2-haloergolines and 2-haloergolenes and process for the preparation thereof |
| YU39278B (en) * | 1976-12-22 | 1984-10-31 | Lek Tovarna Farmacevtskih | Process for preparing 5-bromo nicotinic acid esters |
-
1986
- 1986-05-21 GB GB868612366A patent/GB8612366D0/en active Pending
-
1987
- 1987-05-18 NZ NZ220341A patent/NZ220341A/xx unknown
- 1987-05-18 AU AU73168/87A patent/AU588109B2/en not_active Ceased
- 1987-05-18 FI FI872174A patent/FI85142C/fi not_active IP Right Cessation
- 1987-05-18 IE IE129187A patent/IE60655B1/en not_active IP Right Cessation
- 1987-05-18 IL IL82556A patent/IL82556A/xx not_active IP Right Cessation
- 1987-05-18 JP JP62120989A patent/JPH0723375B2/ja not_active Expired - Lifetime
- 1987-05-19 SU SU874202582A patent/SU1549482A3/ru active
- 1987-05-19 AT AT87107280T patent/ATE82287T1/de active
- 1987-05-19 CA CA000537336A patent/CA1292224C/en not_active Expired - Fee Related
- 1987-05-19 DK DK254687A patent/DK169818B1/da not_active IP Right Cessation
- 1987-05-19 ES ES87107280T patent/ES2052512T3/es not_active Expired - Lifetime
- 1987-05-19 EP EP87107280A patent/EP0249761B1/en not_active Expired - Lifetime
- 1987-05-19 KR KR1019870004930A patent/KR950006866B1/ko not_active IP Right Cessation
- 1987-05-19 DE DE8787107280T patent/DE3782548T2/de not_active Expired - Fee Related
- 1987-05-19 PT PT84897A patent/PT84897B/pt not_active IP Right Cessation
- 1987-05-19 ZA ZA873592A patent/ZA873592B/xx unknown
- 1987-05-20 HU HU872263A patent/HU196069B/hu not_active IP Right Cessation
- 1987-05-21 US US07/052,380 patent/US4785001A/en not_active Expired - Lifetime
-
1992
- 1992-11-19 GR GR920402659T patent/GR3006298T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3006298T3 (ko) | 1993-06-21 |
| JPS62294682A (ja) | 1987-12-22 |
| IL82556A (en) | 1991-06-10 |
| IL82556A0 (en) | 1987-11-30 |
| HUT44542A (en) | 1988-03-28 |
| FI872174A (fi) | 1987-11-22 |
| ES2052512T3 (es) | 1994-07-16 |
| KR950006866B1 (ko) | 1995-06-23 |
| NZ220341A (en) | 1989-06-28 |
| PT84897A (en) | 1987-06-01 |
| AU7316887A (en) | 1987-11-26 |
| FI85142B (fi) | 1991-11-29 |
| AU588109B2 (en) | 1989-09-07 |
| EP0249761B1 (en) | 1992-11-11 |
| EP0249761A2 (en) | 1987-12-23 |
| DE3782548T2 (de) | 1993-04-22 |
| CA1292224C (en) | 1991-11-19 |
| IE871291L (en) | 1987-11-21 |
| IE60655B1 (en) | 1994-08-10 |
| HU196069B (en) | 1988-09-28 |
| DK254687D0 (da) | 1987-05-19 |
| FI872174A0 (fi) | 1987-05-18 |
| ATE82287T1 (de) | 1992-11-15 |
| FI85142C (fi) | 1992-03-10 |
| ZA873592B (en) | 1987-11-12 |
| DE3782548D1 (de) | 1992-12-17 |
| EP0249761A3 (en) | 1989-05-10 |
| SU1549482A3 (ru) | 1990-03-07 |
| JPH0723375B2 (ja) | 1995-03-15 |
| PT84897B (pt) | 1990-02-08 |
| DK254687A (da) | 1987-11-22 |
| KR870011134A (ko) | 1987-12-21 |
| GB8612366D0 (en) | 1986-06-25 |
| US4785001A (en) | 1988-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |