DK169486A - Substituerede n-((4-piperidinyl)alkyl)-bicyklisk kondenseret oxazol- og thiazolaminer - Google Patents

Substituerede n-((4-piperidinyl)alkyl)-bicyklisk kondenseret oxazol- og thiazolaminer Download PDF

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Publication number
DK169486A
DK169486A DK169486A DK169486A DK169486A DK 169486 A DK169486 A DK 169486A DK 169486 A DK169486 A DK 169486A DK 169486 A DK169486 A DK 169486A DK 169486 A DK169486 A DK 169486A
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DK
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Prior art keywords
thiazolamines
piperidinyl
alkyl
substituted
compounds
Prior art date
Application number
DK169486A
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English (en)
Other versions
DK165183C (da
DK165183B (da
DK169486D0 (da
Inventor
Frans Eduard Janssens
Theophilus Theresia Offenwert
Raymond Antoine Stokbroekx
Bernard Robin Boar
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of DK169486D0 publication Critical patent/DK169486D0/da
Publication of DK169486A publication Critical patent/DK169486A/da
Publication of DK165183B publication Critical patent/DK165183B/da
Application granted granted Critical
Publication of DK165183C publication Critical patent/DK165183C/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
DK169486A 1985-04-15 1986-04-14 N-oe(4-piperidinyl)alkylaa-bicyklisk kondenseret oxazol- og thiazolaminforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse DK165183C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72340085A 1985-04-15 1985-04-15
US72340085 1985-04-15

Publications (4)

Publication Number Publication Date
DK169486D0 DK169486D0 (da) 1986-04-14
DK169486A true DK169486A (da) 1986-10-16
DK165183B DK165183B (da) 1992-10-19
DK165183C DK165183C (da) 1993-03-15

Family

ID=24906098

Family Applications (1)

Application Number Title Priority Date Filing Date
DK169486A DK165183C (da) 1985-04-15 1986-04-14 N-oe(4-piperidinyl)alkylaa-bicyklisk kondenseret oxazol- og thiazolaminforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse

Country Status (21)

Country Link
EP (1) EP0199400B1 (da)
JP (1) JPH08824B2 (da)
KR (1) KR930005004B1 (da)
CN (1) CN1019393B (da)
AT (1) ATE56972T1 (da)
AU (1) AU582642B2 (da)
CA (1) CA1271474A (da)
DE (1) DE3674448D1 (da)
DK (1) DK165183C (da)
ES (1) ES8702403A1 (da)
FI (1) FI82047C (da)
GR (1) GR861014B (da)
HU (1) HU196393B (da)
IE (1) IE59040B1 (da)
IL (1) IL78487A (da)
NO (1) NO163818C (da)
NZ (1) NZ215700A (da)
PH (1) PH26181A (da)
PT (1) PT82368B (da)
SU (1) SU1524809A3 (da)
ZA (1) ZA862776B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120843A (en) * 1987-04-27 1992-06-09 Upjohn Pharmaceutically active amines
IL90337A0 (en) * 1988-05-24 1989-12-15 Pfizer Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
US5089637A (en) * 1990-03-21 1992-02-18 Pfizer Inc. Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde
KR100190299B1 (ko) * 1990-07-19 1999-06-01 디르크 반테 신규한 옥사졸릴 유도체
FR2672888B1 (fr) * 1991-02-14 1994-02-04 Fabre Medicament Pierre Nouvelles urees et thiourees, leur preparation et leur application en therapeutique.
ZW1992A1 (en) * 1991-02-25 1993-09-22 Janssen Pharmaceutica Nv 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol
DE4120322A1 (de) * 1991-06-20 1992-12-24 Bayer Ag Aminomethyl-substituierte 2,3-dihydropyrano(2,3-b)pyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
WO1994020476A1 (en) * 1993-03-02 1994-09-15 Fujisawa Pharmaceutical Co., Ltd. Novel heterocyclic compound
TW282469B (da) * 1993-06-11 1996-08-01 Janssen Pharmaceutica Nv
FR2753970B1 (fr) * 1996-10-01 1998-10-30 Synthelabo Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique
JP2000224822A (ja) 1998-06-29 2000-08-11 Mitsubishi Electric Corp 電動パワーステアリング装置用モータ
MXPA02012596A (es) 2000-06-21 2003-04-10 Hoffmann La Roche Derivados de benzotiazol.
FR2821356A1 (fr) 2001-02-23 2002-08-30 Cerep Nouveaux derives d'arylcarbamates et d'arylurees, preparations et utilisations
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
PT1753760E (pt) 2004-05-24 2008-02-12 Hoffmann La Roche '' - metoxi - 7 - morfolin - 4 - il - benzotiazol - 2 - il) - amida do ácido 4 - hidroxi - 4 - metil - piperidina - 1 - carboxílico''
DE602005008095D1 (de) 2004-11-05 2008-08-21 Hoffmann La Roche Verfahren zur herstellung von isonikotinsäurederivaten
RU2412943C2 (ru) 2005-03-23 2011-02-27 Ф. Хоффманн-Ля Рош Аг ПРОИЗВОДНЫЕ АЦЕТИЛЕНИЛ-ПИРАЗОЛО-ПИРИМИДИНА В КАЧЕСТВЕ АНТАГОНИСТОВ mGluR2
ATE463495T1 (de) 2005-09-27 2010-04-15 Hoffmann La Roche Oxadiazolylpyrazolopyrimidine als mglur2- antagonisten

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4035369A (en) * 1975-10-08 1977-07-12 Janssen Pharmaceutica N.V. 1-Benzazolylalkyl-4-substituted-piperidines
DE2545645C2 (de) * 1975-10-11 1983-04-14 Bayer Ag, 5090 Leverkusen Thiazolinylamino-piperidin-Derivate
CA1140119A (en) * 1978-04-03 1983-01-25 Joseph Torremans N-heterocyclyl-4-piperidinamines
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives

Also Published As

Publication number Publication date
HU196393B (en) 1988-11-28
KR860008173A (ko) 1986-11-12
EP0199400A2 (en) 1986-10-29
CN1019393B (zh) 1992-12-09
ES8702403A1 (es) 1987-01-01
DE3674448D1 (de) 1990-10-31
SU1524809A3 (ru) 1989-11-23
JPS62129282A (ja) 1987-06-11
FI82047C (fi) 1991-01-10
IE59040B1 (en) 1993-12-15
KR930005004B1 (ko) 1993-06-11
DK165183C (da) 1993-03-15
HUT40633A (en) 1987-01-28
FI861562A0 (fi) 1986-04-14
JPH08824B2 (ja) 1996-01-10
GR861014B (en) 1986-08-07
EP0199400A3 (en) 1987-08-19
NO861442L (no) 1986-10-16
PT82368A (en) 1986-05-01
AU5613586A (en) 1986-10-23
FI82047B (fi) 1990-09-28
NO163818B (no) 1990-04-17
FI861562A (fi) 1986-10-16
IL78487A0 (en) 1986-08-31
PT82368B (pt) 1988-05-27
DK165183B (da) 1992-10-19
CN86102349A (zh) 1986-11-19
ES553936A0 (es) 1987-01-01
DK169486D0 (da) 1986-04-14
PH26181A (en) 1992-03-18
IE860967L (en) 1986-10-15
ATE56972T1 (de) 1990-10-15
AU582642B2 (en) 1989-04-06
EP0199400B1 (en) 1990-09-26
CA1271474A (en) 1990-07-10
NO163818C (no) 1990-07-25
ZA862776B (en) 1987-11-25
NZ215700A (en) 1988-07-28
IL78487A (en) 1989-12-15

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B1 Patent granted (law 1993)
PBP Patent lapsed
PBP Patent lapsed

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