GR861014B - Substituted n-((4-piperidinyl)alkyl) bicyclic condensed oxazol-and thiazolamines - Google Patents

Substituted n-((4-piperidinyl)alkyl) bicyclic condensed oxazol-and thiazolamines

Info

Publication number
GR861014B
GR861014B GR861014A GR860101014A GR861014B GR 861014 B GR861014 B GR 861014B GR 861014 A GR861014 A GR 861014A GR 860101014 A GR860101014 A GR 860101014A GR 861014 B GR861014 B GR 861014B
Authority
GR
Greece
Prior art keywords
thiazolamines
piperidinyl
alkyl
substituted
compounds
Prior art date
Application number
GR861014A
Other languages
English (en)
Inventor
Janssens Eduard Frans
Offenwert Van Maria Thephilus
Stokbroekx Antoine Raymond
Boar Robin Bernard
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of GR861014B publication Critical patent/GR861014B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
GR861014A 1985-04-15 1986-04-16 Substituted n-((4-piperidinyl)alkyl) bicyclic condensed oxazol-and thiazolamines GR861014B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72340085A 1985-04-15 1985-04-15

Publications (1)

Publication Number Publication Date
GR861014B true GR861014B (en) 1986-08-07

Family

ID=24906098

Family Applications (1)

Application Number Title Priority Date Filing Date
GR861014A GR861014B (en) 1985-04-15 1986-04-16 Substituted n-((4-piperidinyl)alkyl) bicyclic condensed oxazol-and thiazolamines

Country Status (21)

Country Link
EP (1) EP0199400B1 (el)
JP (1) JPH08824B2 (el)
KR (1) KR930005004B1 (el)
CN (1) CN1019393B (el)
AT (1) ATE56972T1 (el)
AU (1) AU582642B2 (el)
CA (1) CA1271474A (el)
DE (1) DE3674448D1 (el)
DK (1) DK165183C (el)
ES (1) ES8702403A1 (el)
FI (1) FI82047C (el)
GR (1) GR861014B (el)
HU (1) HU196393B (el)
IE (1) IE59040B1 (el)
IL (1) IL78487A (el)
NO (1) NO163818C (el)
NZ (1) NZ215700A (el)
PH (1) PH26181A (el)
PT (1) PT82368B (el)
SU (1) SU1524809A3 (el)
ZA (1) ZA862776B (el)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120843A (en) * 1987-04-27 1992-06-09 Upjohn Pharmaceutically active amines
IL90337A0 (en) * 1988-05-24 1989-12-15 Pfizer Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
US5089637A (en) * 1990-03-21 1992-02-18 Pfizer Inc. Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde
KR100190299B1 (ko) * 1990-07-19 1999-06-01 디르크 반테 신규한 옥사졸릴 유도체
FR2672888B1 (fr) * 1991-02-14 1994-02-04 Fabre Medicament Pierre Nouvelles urees et thiourees, leur preparation et leur application en therapeutique.
ZW1992A1 (en) * 1991-02-25 1993-09-22 Janssen Pharmaceutica Nv 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol
DE4120322A1 (de) * 1991-06-20 1992-12-24 Bayer Ag Aminomethyl-substituierte 2,3-dihydropyrano(2,3-b)pyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
AU4982293A (en) * 1993-03-02 1994-09-26 Fujisawa Pharmaceutical Co., Ltd. Novel heterocyclic compound
TW282469B (el) * 1993-06-11 1996-08-01 Janssen Pharmaceutica Nv
FR2753970B1 (fr) * 1996-10-01 1998-10-30 Synthelabo Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique
JP2000224822A (ja) 1998-06-29 2000-08-11 Mitsubishi Electric Corp 電動パワーステアリング装置用モータ
IL153278A0 (en) 2000-06-21 2003-07-06 Hoffmann La Roche Benzothiazole derivatives
FR2821356A1 (fr) 2001-02-23 2002-08-30 Cerep Nouveaux derives d'arylcarbamates et d'arylurees, preparations et utilisations
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
EA011279B1 (ru) 2004-05-24 2009-02-27 Ф. Хоффманн-Ля Рош Аг (4-метокси-7-морфолин-4-илбензотиазол-2-ил)-амид 4-гидрокси-4-метилпиперидин-1-карбоновой кислоты
US7459563B2 (en) 2004-11-05 2008-12-02 Hoffmann-La Roche Inc. Process for the preparation of isonicotinic acid derivatives
PL1863818T3 (pl) 2005-03-23 2010-08-31 Hoffmann La Roche Pochodne acetylenylo-pirazolo-pirymidyny jako antagoniści MGLUR2
ES2340321T3 (es) 2005-09-27 2010-06-01 F.Hoffmann-La Roche Ag Oxadiazolilpirazolo-pirimidinas, como antagonistas de mglur2.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4035369A (en) * 1975-10-08 1977-07-12 Janssen Pharmaceutica N.V. 1-Benzazolylalkyl-4-substituted-piperidines
DE2545645C2 (de) * 1975-10-11 1983-04-14 Bayer Ag, 5090 Leverkusen Thiazolinylamino-piperidin-Derivate
CA1140119A (en) * 1978-04-03 1983-01-25 Joseph Torremans N-heterocyclyl-4-piperidinamines
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives

Also Published As

Publication number Publication date
ES8702403A1 (es) 1987-01-01
FI82047C (fi) 1991-01-10
SU1524809A3 (ru) 1989-11-23
NO163818B (no) 1990-04-17
JPH08824B2 (ja) 1996-01-10
ZA862776B (en) 1987-11-25
NO163818C (no) 1990-07-25
IE59040B1 (en) 1993-12-15
JPS62129282A (ja) 1987-06-11
ES553936A0 (es) 1987-01-01
NZ215700A (en) 1988-07-28
FI861562A (fi) 1986-10-16
IL78487A0 (en) 1986-08-31
ATE56972T1 (de) 1990-10-15
DK165183C (da) 1993-03-15
PH26181A (en) 1992-03-18
HUT40633A (en) 1987-01-28
CN86102349A (zh) 1986-11-19
FI82047B (fi) 1990-09-28
CA1271474A (en) 1990-07-10
AU5613586A (en) 1986-10-23
AU582642B2 (en) 1989-04-06
EP0199400A3 (en) 1987-08-19
KR860008173A (ko) 1986-11-12
KR930005004B1 (ko) 1993-06-11
CN1019393B (zh) 1992-12-09
EP0199400B1 (en) 1990-09-26
PT82368A (en) 1986-05-01
HU196393B (en) 1988-11-28
DK165183B (da) 1992-10-19
IL78487A (en) 1989-12-15
FI861562A0 (fi) 1986-04-14
NO861442L (no) 1986-10-16
DE3674448D1 (de) 1990-10-31
PT82368B (pt) 1988-05-27
DK169486D0 (da) 1986-04-14
DK169486A (da) 1986-10-16
EP0199400A2 (en) 1986-10-29
IE860967L (en) 1986-10-15

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