DK165183C - N-oe(4-piperidinyl)alkylaa-bicyklisk kondenseret oxazol- og thiazolaminforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse - Google Patents

N-oe(4-piperidinyl)alkylaa-bicyklisk kondenseret oxazol- og thiazolaminforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse

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Publication number
DK165183C
DK165183C DK169486A DK169486A DK165183C DK 165183 C DK165183 C DK 165183C DK 169486 A DK169486 A DK 169486A DK 169486 A DK169486 A DK 169486A DK 165183 C DK165183 C DK 165183C
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DK
Denmark
Prior art keywords
compounds
piperidinyl
alkylaa
bicyclic condensed
chem
Prior art date
Application number
DK169486A
Other languages
English (en)
Other versions
DK169486A (da
DK165183B (da
DK169486D0 (da
Inventor
Frans Eduard Janssens
Theophilus Theresia Offenwert
Raymond Antoine Stokbroekx
Bernard Robin Boar
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of DK169486D0 publication Critical patent/DK169486D0/da
Publication of DK169486A publication Critical patent/DK169486A/da
Publication of DK165183B publication Critical patent/DK165183B/da
Application granted granted Critical
Publication of DK165183C publication Critical patent/DK165183C/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK169486A 1985-04-15 1986-04-14 N-oe(4-piperidinyl)alkylaa-bicyklisk kondenseret oxazol- og thiazolaminforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse DK165183C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72340085A 1985-04-15 1985-04-15
US72340085 1985-04-15

Publications (4)

Publication Number Publication Date
DK169486D0 DK169486D0 (da) 1986-04-14
DK169486A DK169486A (da) 1986-10-16
DK165183B DK165183B (da) 1992-10-19
DK165183C true DK165183C (da) 1993-03-15

Family

ID=24906098

Family Applications (1)

Application Number Title Priority Date Filing Date
DK169486A DK165183C (da) 1985-04-15 1986-04-14 N-oe(4-piperidinyl)alkylaa-bicyklisk kondenseret oxazol- og thiazolaminforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse

Country Status (21)

Country Link
EP (1) EP0199400B1 (da)
JP (1) JPH08824B2 (da)
KR (1) KR930005004B1 (da)
CN (1) CN1019393B (da)
AT (1) ATE56972T1 (da)
AU (1) AU582642B2 (da)
CA (1) CA1271474A (da)
DE (1) DE3674448D1 (da)
DK (1) DK165183C (da)
ES (1) ES8702403A1 (da)
FI (1) FI82047C (da)
GR (1) GR861014B (da)
HU (1) HU196393B (da)
IE (1) IE59040B1 (da)
IL (1) IL78487A (da)
NO (1) NO163818C (da)
NZ (1) NZ215700A (da)
PH (1) PH26181A (da)
PT (1) PT82368B (da)
SU (1) SU1524809A3 (da)
ZA (1) ZA862776B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120843A (en) * 1987-04-27 1992-06-09 Upjohn Pharmaceutically active amines
IL90337A0 (en) * 1988-05-24 1989-12-15 Pfizer Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
US5089637A (en) * 1990-03-21 1992-02-18 Pfizer Inc. Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde
KR100190299B1 (ko) * 1990-07-19 1999-06-01 디르크 반테 신규한 옥사졸릴 유도체
FR2672888B1 (fr) * 1991-02-14 1994-02-04 Fabre Medicament Pierre Nouvelles urees et thiourees, leur preparation et leur application en therapeutique.
ZW1992A1 (en) * 1991-02-25 1993-09-22 Janssen Pharmaceutica Nv 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol
DE4120322A1 (de) * 1991-06-20 1992-12-24 Bayer Ag Aminomethyl-substituierte 2,3-dihydropyrano(2,3-b)pyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
AU4982293A (en) * 1993-03-02 1994-09-26 Fujisawa Pharmaceutical Co., Ltd. Novel heterocyclic compound
TW282469B (da) * 1993-06-11 1996-08-01 Janssen Pharmaceutica Nv
FR2753970B1 (fr) * 1996-10-01 1998-10-30 Synthelabo Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique
JP2000224822A (ja) 1998-06-29 2000-08-11 Mitsubishi Electric Corp 電動パワーステアリング装置用モータ
PL207384B1 (pl) 2000-06-21 2010-12-31 Hoffmann La Roche Pochodne benzotiazolu, sposób ich wytwarzania, lek i ich zastosowanie do wytwarzania leku
FR2821356A1 (fr) 2001-02-23 2002-08-30 Cerep Nouveaux derives d'arylcarbamates et d'arylurees, preparations et utilisations
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
PL1753760T3 (pl) 2004-05-24 2008-06-30 Hoffmann La Roche (4-metoksy-7-morffolin-4-ylobenzatiazol-2-ilo)amid kwasu 4-hydroksy-4-metylopiperydyno-1-karboksylowego
EP1812392B1 (en) 2004-11-05 2008-07-09 F.Hoffmann-La Roche Ag Process for preparation of isonicotinic acid derivatives
CN101180299B (zh) 2005-03-23 2010-12-15 弗·哈夫曼-拉罗切有限公司 作为mglur2拮抗剂的乙炔基-吡唑并嘧啶衍生物
ES2340321T3 (es) 2005-09-27 2010-06-01 F.Hoffmann-La Roche Ag Oxadiazolilpirazolo-pirimidinas, como antagonistas de mglur2.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4035369A (en) * 1975-10-08 1977-07-12 Janssen Pharmaceutica N.V. 1-Benzazolylalkyl-4-substituted-piperidines
DE2545645C2 (de) * 1975-10-11 1983-04-14 Bayer Ag, 5090 Leverkusen Thiazolinylamino-piperidin-Derivate
CA1140119A (en) * 1978-04-03 1983-01-25 Joseph Torremans N-heterocyclyl-4-piperidinamines
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives

Also Published As

Publication number Publication date
JPS62129282A (ja) 1987-06-11
CA1271474A (en) 1990-07-10
KR860008173A (ko) 1986-11-12
ES553936A0 (es) 1987-01-01
IL78487A0 (en) 1986-08-31
FI82047C (fi) 1991-01-10
GR861014B (en) 1986-08-07
AU5613586A (en) 1986-10-23
EP0199400A3 (en) 1987-08-19
DK169486A (da) 1986-10-16
ZA862776B (en) 1987-11-25
ES8702403A1 (es) 1987-01-01
PT82368B (pt) 1988-05-27
EP0199400B1 (en) 1990-09-26
PT82368A (en) 1986-05-01
PH26181A (en) 1992-03-18
JPH08824B2 (ja) 1996-01-10
SU1524809A3 (ru) 1989-11-23
NO163818C (no) 1990-07-25
KR930005004B1 (ko) 1993-06-11
HUT40633A (en) 1987-01-28
ATE56972T1 (de) 1990-10-15
CN1019393B (zh) 1992-12-09
NZ215700A (en) 1988-07-28
FI861562A (fi) 1986-10-16
IE59040B1 (en) 1993-12-15
DE3674448D1 (de) 1990-10-31
DK165183B (da) 1992-10-19
IL78487A (en) 1989-12-15
HU196393B (en) 1988-11-28
EP0199400A2 (en) 1986-10-29
NO861442L (no) 1986-10-16
NO163818B (no) 1990-04-17
DK169486D0 (da) 1986-04-14
AU582642B2 (en) 1989-04-06
IE860967L (en) 1986-10-15
FI861562A0 (fi) 1986-04-14
CN86102349A (zh) 1986-11-19
FI82047B (fi) 1990-09-28

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