DK169239B1 - Pyrrolo[1,2-a][4,1]benzoxazepiner og salte deraf, deres fremstilling og farmaceutiske præparater med indhold deraf - Google Patents

Pyrrolo[1,2-a][4,1]benzoxazepiner og salte deraf, deres fremstilling og farmaceutiske præparater med indhold deraf Download PDF

Info

Publication number
DK169239B1
DK169239B1 DK029587A DK29587A DK169239B1 DK 169239 B1 DK169239 B1 DK 169239B1 DK 029587 A DK029587 A DK 029587A DK 29587 A DK29587 A DK 29587A DK 169239 B1 DK169239 B1 DK 169239B1
Authority
DK
Denmark
Prior art keywords
formula
compound
lower alkyl
hydrogen
pharmaceutically acceptable
Prior art date
Application number
DK029587A
Other languages
Danish (da)
English (en)
Other versions
DK29587D0 (da
DK29587A (da
Inventor
Jan William Francis Wasley
Jon Norman
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK29587D0 publication Critical patent/DK29587D0/da
Publication of DK29587A publication Critical patent/DK29587A/da
Application granted granted Critical
Publication of DK169239B1 publication Critical patent/DK169239B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK029587A 1986-01-21 1987-01-20 Pyrrolo[1,2-a][4,1]benzoxazepiner og salte deraf, deres fremstilling og farmaceutiske præparater med indhold deraf DK169239B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82111086 1986-01-21
US06/821,110 US4758559A (en) 1986-01-21 1986-01-21 Pyrrolo[1,2-a] [4,1]benzoxazepine derivatives useful as calmodulin and histamine inhibitors

Publications (3)

Publication Number Publication Date
DK29587D0 DK29587D0 (da) 1987-01-20
DK29587A DK29587A (da) 1987-07-22
DK169239B1 true DK169239B1 (da) 1994-09-19

Family

ID=25232538

Family Applications (1)

Application Number Title Priority Date Filing Date
DK029587A DK169239B1 (da) 1986-01-21 1987-01-20 Pyrrolo[1,2-a][4,1]benzoxazepiner og salte deraf, deres fremstilling og farmaceutiske præparater med indhold deraf

Country Status (25)

Country Link
US (1) US4758559A (es)
EP (1) EP0233483B1 (es)
JP (2) JPH0780888B2 (es)
KR (1) KR900004148B1 (es)
AT (1) ATE62244T1 (es)
AU (1) AU598510B2 (es)
CA (1) CA1273335A (es)
CY (1) CY1749A (es)
DD (1) DD257430A5 (es)
DE (1) DE3768978D1 (es)
DK (1) DK169239B1 (es)
ES (1) ES2039363T3 (es)
FI (1) FI86636C (es)
GR (1) GR3001737T3 (es)
HK (1) HK24194A (es)
HU (1) HU198061B (es)
IE (1) IE59653B1 (es)
IL (1) IL81302A (es)
MA (1) MA20857A1 (es)
MY (1) MY100914A (es)
PH (1) PH25148A (es)
PT (1) PT84136B (es)
TN (1) TNSN87003A1 (es)
ZA (1) ZA87389B (es)
ZW (1) ZW787A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69332792T2 (de) * 1992-04-20 2004-01-15 Takeda Chemical Industries Ltd 4,1-Benzoxazepinderivate als Squalen-Synthetase Inhibitoren und ihre Verwendung zur Behandlung von Hypercholesterämie und als Fungizide
US5452434A (en) * 1992-07-14 1995-09-19 Advanced Micro Devices, Inc. Clock control for power savings in high performance central processing units
USRE39300E1 (en) 1993-01-28 2006-09-19 Virginia Commonwealth University Medical College Of Virginia Inhibiting the development of tolerance to and/or dependence on an addictive substance
US5321012A (en) * 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
US5439524A (en) * 1993-04-05 1995-08-08 Vlsi Technology, Inc. Plasma processing apparatus
US5698518A (en) * 1994-03-30 1997-12-16 Oklahoma Medical Research Foundation Method for regulating inflammation and tumor growth with calmodulin, calmodulin analogues or calmodulin antagonists
US5624902A (en) * 1995-06-07 1997-04-29 Torrey Pines Institute For Molecular Studies Peptide inhibitors of calmodulin
US6423329B1 (en) 1999-02-12 2002-07-23 The Procter & Gamble Company Skin sanitizing compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053599A (en) * 1976-02-26 1977-10-11 American Hoechst Corporation Piperazionalkylpyrrolobenzoxazalkanes
US4029672A (en) * 1976-02-26 1977-06-14 American Hoechst Corporation Aminoalkylpyrrolobenzoxazalkanes
US4045448A (en) * 1976-02-26 1977-08-30 American Hoechst Corporation Pyrrolo[2,1-c][1,4]benzoxazepine and benzoxazocine derivatives
US4169095A (en) * 1977-01-19 1979-09-25 American Hoechst Corporation Process for preparing aminoalkylpyrrolobenzoxazalkanes
US4608374A (en) * 1983-11-07 1986-08-26 Hoechst-Roussel Pharmaceuticals Inc. 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents

Also Published As

Publication number Publication date
MA20857A1 (fr) 1987-10-01
AU6781387A (en) 1987-07-23
MY100914A (en) 1991-05-31
FI86636B (fi) 1992-06-15
FI86636C (fi) 1992-09-25
US4758559A (en) 1988-07-19
IL81302A0 (en) 1987-08-31
ZW787A1 (en) 1987-08-12
PT84136A (en) 1987-02-01
DE3768978D1 (de) 1991-05-08
JPH0826028B2 (ja) 1996-03-13
TNSN87003A1 (fr) 1990-01-01
JPS62169791A (ja) 1987-07-25
CY1749A (en) 1994-06-03
AU598510B2 (en) 1990-06-28
GR3001737T3 (en) 1992-11-23
PT84136B (pt) 1989-07-31
JPH0789966A (ja) 1995-04-04
IE870139L (en) 1987-07-21
KR870007181A (ko) 1987-08-17
CA1273335A (en) 1990-08-28
DK29587D0 (da) 1987-01-20
EP0233483A2 (de) 1987-08-26
JPH0780888B2 (ja) 1995-08-30
KR900004148B1 (ko) 1990-06-16
IE59653B1 (en) 1994-03-09
HU198061B (en) 1989-07-28
DD257430A5 (de) 1988-06-15
PH25148A (en) 1991-03-13
DK29587A (da) 1987-07-22
FI870207A (fi) 1987-07-22
EP0233483B1 (de) 1991-04-03
FI870207A0 (fi) 1987-01-19
ES2039363T3 (es) 1995-04-01
IL81302A (en) 1990-11-29
HUT45259A (en) 1988-06-28
HK24194A (en) 1994-03-25
ZA87389B (en) 1987-11-25
EP0233483A3 (en) 1988-10-19
ATE62244T1 (de) 1991-04-15

Similar Documents

Publication Publication Date Title
US3014911A (en) Derivatives of dibenzo[a, e]cycloheptatriene
US4997834A (en) Trans-4-amino(alkyl)-1-pyridylcarbamoylcyclohexane compounds and pharmaceutical use thereof
SK31793A3 (en) Pyridine and pyridine n-oxide derivatives of diaryl methyl piperidines and piperazines and compositions and methods of use thereof
SK281941B6 (sk) Deriváty kyseliny indol-2-karboxylovej, ich použitie, spôsob ich prípravy a farmaceutický prípravok s ich obsahom
Cale Jr et al. Benzo-and pyrido-1, 4-oxazepin-5-ones and-thiones: synthesis and structure-activity relationships of a new series of H1-antihistamines
JPH01104069A (ja) １−［（２−ピリミジニアル）アミノアルキル］ピペリジン類、その製造方法およびその医薬への応用
DK169239B1 (da) Pyrrolo[1,2-a][4,1]benzoxazepiner og salte deraf, deres fremstilling og farmaceutiske præparater med indhold deraf
Chapleo et al. Heteroaromatic analogs of the. alpha. 2-adrenoreceptor partial agonist clonidine
US4021552A (en) 10-[ω-(BENZOYLPIPERIDINYL)ALKYL]PHENOTHIAZINES
JPS63290868A (ja) ジケトピペラジン誘導体およびその塩類
EP0174858B1 (en) Isoindolinone derivatives, production and use thereof
CA1208643A (en) 1,5-diphenyl-pyrazolin-3-one compounds, process and intermediates for preparation thereof and pharmaceutical compositions containing them
EP0107930A2 (en) Fused aromatic oxazepinones and sulphur analogues thereof and their preparation and use in counteracting histamine
US5071858A (en) Antipsychotic benzothiopyranylamines
US4537975A (en) 1-Phenylindazol-3-one compounds
HU188475B (en) Process for producing benzothiopyrano-pyridinones
DK143752B (da) Analogifremgangsmaade til fremstilling af pyridobenzodiazepinoner eller farmakologisk acceptable salte deraf
US5077295A (en) Antipsychoic 4-(4-(3-benzisothiazolyl)-1-piperazinyl)buytl bridged bicycle imides
US4410536A (en) 7,8,9,10-Tetrahydrothieno[3,2-e]pyrido[4,3-b]indole compounds and their anti-depressant use
US3691176A (en) 1-(4-fluorophenoxypropyl)-4-anilino-piperidines
KR830001667B1 (ko) 페닐 퀴놀리지딘의 제조방법
JPS6130588A (ja) ベンゾ〔ｃ〕〔１，８〕ナフチリジン、その製造方法及びその使用、並びにこれらの化合物を含有する調製剤
KR890001184B1 (ko) 융합된 방향족 디아제피논 및 이의 황동족체
JPS6183172A (ja) ジベンゾ〔ｂ，ｆ〕〔１，５〕オキサゾシン誘導体及びその製造法並びにそれを有効成分とする医薬
JPH01246256A (ja) ２−アゼチジノン誘導体

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

Country of ref document: DK