DK168625B1 - Fremgangsmåde til fremstilling af 1,2-substituerede 1,2,3,4,5,6,7,8 octahydroisoquinolinderivater - Google Patents

Fremgangsmåde til fremstilling af 1,2-substituerede 1,2,3,4,5,6,7,8 octahydroisoquinolinderivater Download PDF

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Publication number
DK168625B1
DK168625B1 DK102388A DK102388A DK168625B1 DK 168625 B1 DK168625 B1 DK 168625B1 DK 102388 A DK102388 A DK 102388A DK 102388 A DK102388 A DK 102388A DK 168625 B1 DK168625 B1 DK 168625B1
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DK
Denmark
Prior art keywords
toluene
solution
formula
methyl
xylene
Prior art date
Application number
DK102388A
Other languages
Danish (da)
English (en)
Other versions
DK102388D0 (da
DK102388A (da
Inventor
Philippe Peter
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK102388D0 publication Critical patent/DK102388D0/da
Publication of DK102388A publication Critical patent/DK102388A/da
Application granted granted Critical
Publication of DK168625B1 publication Critical patent/DK168625B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
DK102388A 1987-03-20 1988-02-26 Fremgangsmåde til fremstilling af 1,2-substituerede 1,2,3,4,5,6,7,8 octahydroisoquinolinderivater DK168625B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH106487 1987-03-20
CH106487 1987-03-20

Publications (3)

Publication Number Publication Date
DK102388D0 DK102388D0 (da) 1988-02-26
DK102388A DK102388A (da) 1988-09-21
DK168625B1 true DK168625B1 (da) 1994-05-09

Family

ID=4201606

Family Applications (1)

Application Number Title Priority Date Filing Date
DK102388A DK168625B1 (da) 1987-03-20 1988-02-26 Fremgangsmåde til fremstilling af 1,2-substituerede 1,2,3,4,5,6,7,8 octahydroisoquinolinderivater

Country Status (12)

Country Link
EP (1) EP0283848B1 (ja)
JP (1) JP2507523B2 (ja)
AT (1) ATE63545T1 (ja)
AU (1) AU613605B2 (ja)
CA (1) CA1310012C (ja)
DE (1) DE3862787D1 (ja)
DK (1) DK168625B1 (ja)
HU (1) HU203876B (ja)
IE (1) IE61069B1 (ja)
NZ (1) NZ223879A (ja)
PH (1) PH25036A (ja)
ZA (1) ZA881811B (ja)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE834103C (de) * 1950-01-03 1952-03-17 Bayer Ag Verfahren zur Herstellung von 1-Benzyl-1, 2, 3, 4, 5, 6, 7, 8,-octahydroisochinolin
DE908138C (de) * 1951-01-16 1954-04-01 Hoffmann La Roche Verfahren zur Herstellung von 1-Benzyl-2-alkyl-1,2,3,4,5,6,7,8,-octa-hydroisochinolinen und ihren Salzen
DE1003211B (de) * 1952-06-16 1957-02-28 Hoffmann La Roche Verfahren zur Herstellung von gegebenenfalls im Benzylrest substituierten 1-Benzyl-2-methyl-1,2,3,4,5,6,7,8-octahydro-isochinolinen und deren Salzen
DE955769C (de) * 1953-08-13 1957-01-10 Hoffmann La Roche Verfahren zur Racemisierung von optisch aktiven 1-(p-Methoxybenzyl)-2-methyl-octahydroisochinolinen

Also Published As

Publication number Publication date
CA1310012C (en) 1992-11-10
AU613605B2 (en) 1991-08-08
EP0283848A1 (de) 1988-09-28
JPS63238062A (ja) 1988-10-04
IE61069B1 (en) 1994-09-21
HU203876B (en) 1991-10-28
AU1307488A (en) 1988-09-22
HUT49123A (en) 1989-08-28
NZ223879A (en) 1991-01-29
IE880805L (en) 1988-09-20
JP2507523B2 (ja) 1996-06-12
DE3862787D1 (de) 1991-06-20
ATE63545T1 (de) 1991-06-15
PH25036A (en) 1991-01-28
DK102388D0 (da) 1988-02-26
EP0283848B1 (de) 1991-05-15
DK102388A (da) 1988-09-21
ZA881811B (en) 1988-09-20

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed