DK168437B1 - Tetrahydrobenzothiazolforbindelser, en fremgangsmåde til deres fremstilling, deres anvendelse til fremstilling af et lægemiddel, samt lægemiddel indeholdende sådanne forbindelser. - Google Patents

Tetrahydrobenzothiazolforbindelser, en fremgangsmåde til deres fremstilling, deres anvendelse til fremstilling af et lægemiddel, samt lægemiddel indeholdende sådanne forbindelser. Download PDF

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Publication number
DK168437B1
DK168437B1 DK313587A DK313587A DK168437B1 DK 168437 B1 DK168437 B1 DK 168437B1 DK 313587 A DK313587 A DK 313587A DK 313587 A DK313587 A DK 313587A DK 168437 B1 DK168437 B1 DK 168437B1
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DK
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Prior art keywords
compound
formula
compounds
preparation
alkyl
Prior art date
Application number
DK313587A
Other languages
Danish (da)
English (en)
Other versions
DK313587A (da
DK313587D0 (da
Inventor
Claus Schneider
Herbert Merz
Rainer Sobotta
Rudolf Bauer
Joachim Mierau
Guenter Schingnitz
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of DK313587D0 publication Critical patent/DK313587D0/da
Publication of DK313587A publication Critical patent/DK313587A/da
Application granted granted Critical
Publication of DK168437B1 publication Critical patent/DK168437B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Dental Preparations (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK313587A 1986-06-21 1987-06-19 Tetrahydrobenzothiazolforbindelser, en fremgangsmåde til deres fremstilling, deres anvendelse til fremstilling af et lægemiddel, samt lægemiddel indeholdende sådanne forbindelser. DK168437B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3620813 1986-06-21
DE19863620813 DE3620813A1 (de) 1986-06-21 1986-06-21 Neue tetrahydro-benzothiazole, ihre herstellung und verwendung

Publications (3)

Publication Number Publication Date
DK313587D0 DK313587D0 (da) 1987-06-19
DK313587A DK313587A (da) 1987-12-22
DK168437B1 true DK168437B1 (da) 1994-03-28

Family

ID=6303408

Family Applications (1)

Application Number Title Priority Date Filing Date
DK313587A DK168437B1 (da) 1986-06-21 1987-06-19 Tetrahydrobenzothiazolforbindelser, en fremgangsmåde til deres fremstilling, deres anvendelse til fremstilling af et lægemiddel, samt lægemiddel indeholdende sådanne forbindelser.

Country Status (25)

Country Link
US (1) US4981862A (fi)
EP (1) EP0251077B1 (fi)
JP (1) JPS6317872A (fi)
KR (1) KR950004000B1 (fi)
AT (1) ATE70060T1 (fi)
AU (1) AU593357B2 (fi)
CA (1) CA1322372C (fi)
CS (1) CS451187A3 (fi)
DD (1) DD259623A5 (fi)
DE (2) DE3620813A1 (fi)
DK (1) DK168437B1 (fi)
ES (1) ES2040226T3 (fi)
FI (1) FI88297C (fi)
GR (1) GR3003656T3 (fi)
HU (1) HU204042B (fi)
IE (1) IE60676B1 (fi)
IL (1) IL82925A0 (fi)
NO (1) NO167978C (fi)
NZ (1) NZ220800A (fi)
PH (1) PH24207A (fi)
PL (1) PL150292B1 (fi)
PT (1) PT85100B (fi)
SU (1) SU1494867A3 (fi)
UA (1) UA8032A1 (fi)
ZA (1) ZA874470B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2731619A1 (fr) * 1995-03-14 1996-09-20 Logeais Labor Jacques Compositions pharmaceutiques contenant de la l-etrabamine, leurs utilisations et leurs procedes de preparation
ES2187249B1 (es) * 2000-09-18 2004-09-16 Synthon Bv Procedimiento para la preparacion de 2-amino-6-(alquil)amino-4,5,6,7-tetrahidrobenzotiazoles.
GB0221513D0 (en) * 2002-09-17 2002-10-23 Generics Uk Ltd Novel compounds and processes
KR100715203B1 (ko) * 2003-12-19 2007-05-07 주식회사 코오롱 공기필터용 폴리에스테르 스펀본드 부직포 및 그 제조방법
ITMI20060044A1 (it) * 2006-01-13 2007-07-14 Dipharma Spa Sintesi di intermedi pr la preparazione di pramipexolo
GB0721333D0 (en) * 2007-10-31 2007-12-12 Motac Neuroscience Ltd Medicaments
CN108084115B (zh) * 2017-12-28 2020-03-17 上海博志研新药物技术有限公司 盐酸普拉克索及其中间体的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923677A1 (de) * 1969-05-09 1970-11-19 Bayer Ag Derivate des 2,6-Diaminobenzothiazols
DE2136233A1 (de) * 1971-07-20 1973-02-01 Riedel De Haen Ag Tetrahydrobenzthiazolderivate enthaltende pharmazeutische praeparate
FR2406635A1 (fr) * 1977-10-24 1979-05-18 Logeais Labor Jacques Nouveaux derives du benzo(d)thiazole, leur procede de preparation et leurs applications en therapeutique
FR2459239A1 (fr) * 1979-06-20 1981-01-09 Logeais Labor Jacques Nouveaux derives amines du benzothiazole, leur procede de preparation et leur application en therapeutique
DE3447075A1 (de) * 1984-12-22 1986-07-03 Dr. Karl Thomae Gmbh, 7950 Biberach Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arzneimittel
ATE45735T1 (de) * 1984-12-22 1989-09-15 Thomae Gmbh Dr K Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arnzneimittel.
ZA864626B (en) * 1985-06-24 1988-02-24 Lilly Co Eli Dialkylaminotetrahydrobenzothiazoles and oxazoles

Also Published As

Publication number Publication date
JPS6317872A (ja) 1988-01-25
CS276376B6 (en) 1992-05-13
IE871633L (en) 1987-12-21
PL266361A1 (en) 1988-10-13
FI872719A (fi) 1987-12-22
ATE70060T1 (de) 1991-12-15
SU1494867A3 (ru) 1989-07-15
CA1322372C (en) 1993-09-21
NZ220800A (en) 1989-12-21
AU593357B2 (en) 1990-02-08
PT85100B (pt) 1994-10-31
PH24207A (en) 1990-04-10
DK313587A (da) 1987-12-22
FI88297C (fi) 1993-04-26
NO872574L (no) 1987-12-22
HUT47091A (en) 1989-01-30
EP0251077A1 (de) 1988-01-07
NO872574D0 (no) 1987-06-19
FI872719A0 (fi) 1987-06-18
AU7457887A (en) 1987-12-24
EP0251077B1 (de) 1991-12-04
GR3003656T3 (fi) 1993-03-16
IL82925A0 (en) 1987-12-20
KR880000415A (ko) 1988-03-25
PL150292B1 (en) 1990-05-31
FI88297B (fi) 1993-01-15
ES2040226T3 (es) 1993-10-16
PT85100A (pt) 1988-07-01
HU204042B (en) 1991-11-28
NO167978C (no) 1992-01-02
IE60676B1 (en) 1994-08-10
US4981862A (en) 1991-01-01
DE3620813A1 (de) 1987-12-23
NO167978B (no) 1991-09-23
CS451187A3 (en) 1992-05-13
KR950004000B1 (ko) 1995-04-22
DE3774942D1 (de) 1992-01-16
DD259623A5 (de) 1988-08-31
UA8032A1 (uk) 1995-12-26
ZA874470B (en) 1989-02-22
DK313587D0 (da) 1987-06-19

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed