DK167649B1 - Fast laegemiddeldispersion med forlaenget afgivelse, sekundaer struktur af laegemidlet samt farmaceutisk praeparat indeholdende dispersionen eller strukturen - Google Patents

Fast laegemiddeldispersion med forlaenget afgivelse, sekundaer struktur af laegemidlet samt farmaceutisk praeparat indeholdende dispersionen eller strukturen Download PDF

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Publication number
DK167649B1
DK167649B1 DK264785A DK264785A DK167649B1 DK 167649 B1 DK167649 B1 DK 167649B1 DK 264785 A DK264785 A DK 264785A DK 264785 A DK264785 A DK 264785A DK 167649 B1 DK167649 B1 DK 167649B1
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Denmark
Prior art keywords
active agent
dispersion
compound
pharmaceutical composition
hours
Prior art date
Application number
DK264785A
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Danish (da)
English (en)
Other versions
DK264785D0 (da
DK264785A (da
Inventor
Wolfgang Czarnecki
Jean Claude Gfeller
Hans Peter Bier
Original Assignee
Sandoz Ag
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Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK264785D0 publication Critical patent/DK264785D0/da
Publication of DK264785A publication Critical patent/DK264785A/da
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Publication of DK167649B1 publication Critical patent/DK167649B1/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK264785A 1984-06-14 1985-06-12 Fast laegemiddeldispersion med forlaenget afgivelse, sekundaer struktur af laegemidlet samt farmaceutisk praeparat indeholdende dispersionen eller strukturen DK167649B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3422083 1984-06-14
DE3422083 1984-06-14
DE3442566 1984-11-22
DE3442566 1984-11-22

Publications (3)

Publication Number Publication Date
DK264785D0 DK264785D0 (da) 1985-06-12
DK264785A DK264785A (da) 1985-12-15
DK167649B1 true DK167649B1 (da) 1993-12-06

Family

ID=25822108

Family Applications (1)

Application Number Title Priority Date Filing Date
DK264785A DK167649B1 (da) 1984-06-14 1985-06-12 Fast laegemiddeldispersion med forlaenget afgivelse, sekundaer struktur af laegemidlet samt farmaceutisk praeparat indeholdende dispersionen eller strukturen

Country Status (21)

Country Link
AT (1) AT391806B (pt)
AU (2) AU587190B2 (pt)
BE (1) BE902626A (pt)
CA (1) CA1264441A (pt)
CY (1) CY1635A (pt)
DE (1) DE3520184C2 (pt)
DK (1) DK167649B1 (pt)
ES (1) ES8702141A1 (pt)
FR (1) FR2565822B1 (pt)
GB (3) GB2160100B (pt)
GR (1) GR851430B (pt)
HK (1) HK25192A (pt)
HU (1) HU198844B (pt)
IE (1) IE58834B1 (pt)
IL (1) IL75490A0 (pt)
IT (1) IT1200080B (pt)
LU (1) LU85946A1 (pt)
NL (1) NL194389C (pt)
NZ (1) NZ212390A (pt)
PT (1) PT80635B (pt)
SE (1) SE504583C2 (pt)

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Publication number Priority date Publication date Assignee Title
IT1187751B (it) * 1985-10-15 1987-12-23 Eurand Spa Procedimento per la preparazione di formulazioni solidi di nifedipina ad elevata biodisponibilita' e ad effetto prolungato e formulazioni cosi' ottenute
US4816263A (en) * 1987-10-02 1989-03-28 Alza Corporation Dosage form for treating cardiovascular diseases comprising isradipine
AU3432689A (en) * 1988-03-24 1989-10-16 Bukh Meditec A/S Controlled release composition
GR1000270B (el) * 1988-09-30 1992-05-12 Alza Corp Μορφη δοσολογιας για θεραπεια καρδιαγγειακων ασθενειων.
DK469989D0 (da) * 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
DE4201179A1 (de) * 1992-01-17 1993-07-22 Alfatec Pharma Gmbh Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung
US6726930B1 (en) 1993-09-09 2004-04-27 Penwest Pharmaceuticals Co. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5773025A (en) 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
WO1998001117A1 (en) 1996-07-08 1998-01-15 Edward Mendell Co., Inc. Sustained release matrix for high-dose insoluble drugs
DE19710009A1 (de) * 1997-03-12 1998-09-24 Knoll Ag Mehrphasige wirkstoffhaltige Zubereitungsformen
US6056977A (en) 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
US6787157B1 (en) 1998-03-10 2004-09-07 Abbott Laboratories Multiphase active ingredient-containing formulations
US7001892B1 (en) 1999-06-11 2006-02-21 Purdue Research Foundation Pharmaceutical materials and methods for their preparation and use
EP1189599A2 (en) * 1999-06-11 2002-03-27 Eli Lilly And Company Pharmaceutical materials and methods for their preparation and use
JP3462490B2 (ja) * 1999-08-04 2003-11-05 山之内製薬株式会社 安定な経口用医薬組成物
JP3893058B2 (ja) 1999-09-30 2007-03-14 ペンウェスト ファーマシューティカルズ カンパニー 高度に可溶性の薬物のための徐放性マトリックス系
BR0206825A (pt) * 2001-02-13 2004-02-25 Astrazeneca Ab Formulação de dispersão sólida de liberação modificada, multiparticulada, processo para a preparação da formulação, uso da mesma, tablete, e, métodos para o tratamento de uma doença cardiovascular, e, para o tratamento de câncer
US7135436B2 (en) 2003-05-05 2006-11-14 J.F. Daley International, Ltd. Solid algicide, preparation and usage in recirculating water
EP1690528A1 (de) 2005-02-11 2006-08-16 Abbott GmbH & Co. KG Herstellung von Dosierungsformen mit einer festen Dispersion eines mikrokristallinen Wirkstoffs
JP2010511713A (ja) 2006-12-05 2010-04-15 ランデック コーポレイション 薬物送達
US8399007B2 (en) 2006-12-05 2013-03-19 Landec Corporation Method for formulating a controlled-release pharmaceutical formulation
US8114883B2 (en) 2007-12-04 2012-02-14 Landec Corporation Polymer formulations for delivery of bioactive materials
MX2011001864A (es) 2008-08-20 2011-06-20 Univ Texas Extrusion de fusion en caliente de multiples particulas de liberacion modificada.

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617362A1 (de) * 1967-11-17 1971-03-25 Beiersdorf Ag Verfahren zur Herstellung von Arzneimitteln mit verzoegerter Wirkstoffabgabe in Form von Kapseln
DE2400819C2 (de) * 1974-01-09 1982-04-22 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung fester Zubereitungen von schwerlöslichen Arzneimittelwirkstoffen in feinster Verteilung
DE2546577B2 (de) * 1975-10-17 1981-04-02 Sandoz-Patent-GmbH, 7850 Lörrach Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden
DE2549740A1 (de) * 1975-11-17 1977-05-18 Sandoz Ag Neue galenische formen und verfahren zu deren herstellung
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
CH639659A5 (de) * 1978-12-18 1983-11-30 Sandoz Ag Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.
DK149855C (da) * 1977-06-20 1987-04-21 Sandoz Ag Analogifremgangsmaade til fremstilling af 1,4-dihydropyridinderivater
EP0001247A1 (en) * 1977-09-14 1979-04-04 Kanebo, Ltd. Pharmaceutical preparation containing nifedipine and a method for producing the same.
WO1980001242A1 (en) * 1978-12-21 1980-06-26 Sandoz Ag Galenical preparation
DE2904310A1 (de) * 1979-02-05 1980-08-07 Boehringer Mannheim Gmbh Formlinge mit retardierter wirkstofffreisetzung und verfahren zu deren herstellung
JPS56115726A (en) * 1980-02-20 1981-09-11 Kaken Pharmaceut Co Ltd Pharmaceutical containing nifedipine
DE3033919A1 (de) * 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung
US4442112A (en) * 1981-09-02 1984-04-10 Sandoz Ltd. Dihydropyridine derivatives useful in treating vascular headaches
DE3270785D1 (en) * 1981-10-29 1986-05-28 Bayer Ag Process for preparing solid fast-releasing drug formulations of dihydropyridines
CA1208558A (en) * 1982-10-07 1986-07-29 Kazuo Kigasawa Soft buccal
DE3318649A1 (de) * 1983-05-21 1984-11-22 Bayer Ag, 5090 Leverkusen Zweiphasenformulierung

Also Published As

Publication number Publication date
BE902626A (fr) 1985-12-10
PT80635B (pt) 1987-10-20
IT1200080B (it) 1989-01-05
HK25192A (en) 1992-04-10
PT80635A (en) 1985-07-01
GB8514855D0 (en) 1985-07-17
FR2565822A1 (fr) 1985-12-20
LU85946A1 (fr) 1986-01-24
DK264785D0 (da) 1985-06-12
GB8727056D0 (en) 1987-12-23
DK264785A (da) 1985-12-15
GB8727055D0 (en) 1987-12-23
GB2196852A (en) 1988-05-11
GB2196852B (en) 1989-05-17
IT8548210A0 (it) 1985-06-13
GB2160100B (en) 1989-06-01
NZ212390A (en) 1992-02-25
FR2565822B1 (fr) 1989-02-17
SE504583C2 (sv) 1997-03-10
NL194389C (nl) 2002-03-04
DE3520184C2 (de) 1997-03-13
AT391806B (de) 1990-12-10
IE851460L (en) 1985-12-14
ATA174885A (de) 1990-06-15
ES544075A0 (es) 1987-01-01
AU4348685A (en) 1985-12-19
GR851430B (pt) 1985-11-25
CY1635A (en) 1992-11-06
ES8702141A1 (es) 1987-01-01
NL8501578A (nl) 1986-01-02
HUT40918A (en) 1987-03-30
AU587190B2 (en) 1989-08-10
GB2196851A (en) 1988-05-11
SE8502950L (sv) 1985-12-15
IE58834B1 (en) 1993-11-17
IL75490A0 (en) 1985-10-31
CA1264441A (en) 1990-01-16
NL194389B (nl) 2001-11-01
SE8502950D0 (sv) 1985-06-13
DE3520184A1 (de) 1985-12-19
GB2196851B (en) 1989-06-07
GB2160100A (en) 1985-12-18
AU4454389A (en) 1990-03-22
HU198844B (en) 1989-12-28

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired