JPS56115726A - Pharmaceutical containing nifedipine - Google Patents

Pharmaceutical containing nifedipine

Info

Publication number
JPS56115726A
JPS56115726A JP1919180A JP1919180A JPS56115726A JP S56115726 A JPS56115726 A JP S56115726A JP 1919180 A JP1919180 A JP 1919180A JP 1919180 A JP1919180 A JP 1919180A JP S56115726 A JPS56115726 A JP S56115726A
Authority
JP
Japan
Prior art keywords
nifedipine
polyethylene glycol
viscous substance
pharmaceutical
dimethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1919180A
Other languages
Japanese (ja)
Inventor
Kenji Kono
Yoshitsugu Yamada
Naoko Inaba
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Kaken Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd, Kaken Chemical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Priority to JP1919180A priority Critical patent/JPS56115726A/en
Publication of JPS56115726A publication Critical patent/JPS56115726A/en
Pending legal-status Critical Current

Links

Landscapes

  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)

Abstract

PURPOSE: The titled pharmaceutical, having a high absorption efficiency, stable to light, and easily administrable, and containing nifedipine and polyethylene glycol and/or a specific viscous substance.
CONSTITUTION: A pharmaceutical containing nifedipine [chemical name: dimethyl 2,6-dimethyl-4-(2-nitrophynyl)-1,4-dihydropyridine-3,5-dicarboxylate], useful for the remedy of angina pectoris and hypertension, and having the vasodilator action and polyethylene glycol and/or a viscous substance, e.g. honey or olive oil. The polyethylene glycol or viscous substance or both are used in an amount of preferably 5W20pts.wt. based on 1pt.wt. nifedipine. The nifedipine dissolved in the polyethylene glycol and/or viscous substance in a molecular state or nearly the molecular state is absorbed from the mucous membrane in the mouth or digestive tract rapidly at an increased elution rate. The pharmaceutical is especially stabilized to light compared with a nifedipine solution.
COPYRIGHT: (C)1981,JPO&Japio
JP1919180A 1980-02-20 1980-02-20 Pharmaceutical containing nifedipine Pending JPS56115726A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1919180A JPS56115726A (en) 1980-02-20 1980-02-20 Pharmaceutical containing nifedipine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1919180A JPS56115726A (en) 1980-02-20 1980-02-20 Pharmaceutical containing nifedipine

Publications (1)

Publication Number Publication Date
JPS56115726A true JPS56115726A (en) 1981-09-11

Family

ID=11992443

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1919180A Pending JPS56115726A (en) 1980-02-20 1980-02-20 Pharmaceutical containing nifedipine

Country Status (1)

Country Link
JP (1) JPS56115726A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2555048A1 (en) * 1983-11-17 1985-05-24 Nippon Shinyaku Co Ltd PROCESS FOR THE MANUFACTURE OF NIFEDIPIN COMPOSITIONS AND NOVEL PRODUCTS THUS OBTAINED
US4537898A (en) * 1983-03-03 1985-08-27 Bayer Aktiengesellschaft Liquid formulations of dihydropyridines
FR2565822A1 (en) * 1984-06-14 1985-12-20 Sandoz Sa NEW GALENIC FORM RETARD
US5082655A (en) * 1984-07-23 1992-01-21 Zetachron, Inc. Pharmaceutical composition for drugs subject to supercooling
WO1996023499A1 (en) * 1995-02-02 1996-08-08 Bernard Charles Sherman Extended-release solid oral dosage forms of drugs having low solubility in water
RU2470627C2 (en) * 2007-02-15 2012-12-27 Чоонгвае Фарма Корпорейшн Thixotropic pharmaceutical compositions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS542316A (en) * 1977-06-07 1979-01-09 Yamanouchi Pharmaceut Co Ltd Solid pharmaceutical composition containing nifedipene

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS542316A (en) * 1977-06-07 1979-01-09 Yamanouchi Pharmaceut Co Ltd Solid pharmaceutical composition containing nifedipene

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537898A (en) * 1983-03-03 1985-08-27 Bayer Aktiengesellschaft Liquid formulations of dihydropyridines
FR2555048A1 (en) * 1983-11-17 1985-05-24 Nippon Shinyaku Co Ltd PROCESS FOR THE MANUFACTURE OF NIFEDIPIN COMPOSITIONS AND NOVEL PRODUCTS THUS OBTAINED
FR2565822A1 (en) * 1984-06-14 1985-12-20 Sandoz Sa NEW GALENIC FORM RETARD
US5082655A (en) * 1984-07-23 1992-01-21 Zetachron, Inc. Pharmaceutical composition for drugs subject to supercooling
WO1996023499A1 (en) * 1995-02-02 1996-08-08 Bernard Charles Sherman Extended-release solid oral dosage forms of drugs having low solubility in water
US6132772A (en) * 1995-02-02 2000-10-17 Sherman; Bernard Charles Extended-release solid oral dosage forms of drugs having low solubility in water
RU2470627C2 (en) * 2007-02-15 2012-12-27 Чоонгвае Фарма Корпорейшн Thixotropic pharmaceutical compositions

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