DK167141B1 - Vandige oploesninger af antibiotiket vancomycin-hydrochlorid og fremgangsmaade til lyofilisering deraf - Google Patents

Vandige oploesninger af antibiotiket vancomycin-hydrochlorid og fremgangsmaade til lyofilisering deraf Download PDF

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Publication number
DK167141B1
DK167141B1 DK570588A DK570588A DK167141B1 DK 167141 B1 DK167141 B1 DK 167141B1 DK 570588 A DK570588 A DK 570588A DK 570588 A DK570588 A DK 570588A DK 167141 B1 DK167141 B1 DK 167141B1
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DK
Denmark
Prior art keywords
approx
vancomycin hydrochloride
gel
concentration
ethanol
Prior art date
Application number
DK570588A
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Danish (da)
English (en)
Other versions
DK570588A (da
DK570588D0 (da
Inventor
Robert Lee Robison
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22330088&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK167141(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK570588D0 publication Critical patent/DK570588D0/da
Publication of DK570588A publication Critical patent/DK570588A/da
Application granted granted Critical
Publication of DK167141B1 publication Critical patent/DK167141B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK570588A 1987-10-15 1988-10-13 Vandige oploesninger af antibiotiket vancomycin-hydrochlorid og fremgangsmaade til lyofilisering deraf DK167141B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/109,885 US4885275A (en) 1987-10-15 1987-10-15 Vancomycin-HCL solutions and the lyophilization thereof
US10988587 1987-10-15

Publications (3)

Publication Number Publication Date
DK570588D0 DK570588D0 (da) 1988-10-13
DK570588A DK570588A (da) 1989-04-16
DK167141B1 true DK167141B1 (da) 1993-09-06

Family

ID=22330088

Family Applications (1)

Application Number Title Priority Date Filing Date
DK570588A DK167141B1 (da) 1987-10-15 1988-10-13 Vandige oploesninger af antibiotiket vancomycin-hydrochlorid og fremgangsmaade til lyofilisering deraf

Country Status (17)

Country Link
US (1) US4885275A (ko)
EP (1) EP0318146B1 (ko)
JP (2) JP2883890B2 (ko)
KR (1) KR970007907B1 (ko)
AT (1) ATE74013T1 (ko)
AU (1) AU610936B2 (ko)
CA (1) CA1326211C (ko)
DE (1) DE3869563D1 (ko)
DK (1) DK167141B1 (ko)
ES (1) ES2036690T3 (ko)
GR (1) GR3004155T3 (ko)
HU (1) HU200558B (ko)
IE (1) IE61049B1 (ko)
IL (1) IL88024A (ko)
NZ (1) NZ226550A (ko)
PH (1) PH25109A (ko)
ZA (1) ZA887579B (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03193735A (ja) * 1989-12-22 1991-08-23 Shionogi & Co Ltd グリコペプチド系抗生物質の安定化組成物
CA2238872A1 (en) * 1995-12-01 1997-06-05 Eli Lilly And Company Stable vancomycin hydrochloride solutions
US5786022A (en) * 1996-10-31 1998-07-28 Ethicon, Inc. Coating mixture for surgical articles
US6391851B1 (en) * 1997-03-10 2002-05-21 Fujisawa Pharmaceutical Co., Ltd. Hydrochlorides of vancomycin antibiotics and process for producing the same
WO1999041012A1 (en) * 1998-02-13 1999-08-19 Korea Research Institute Of Chemical Technology A solid catalyst with core-shell catalytic phase and a method of preparation thereof
UA75083C2 (uk) 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
CA2416600A1 (en) 2000-07-24 2003-01-20 Ono Pharmaceutical Co., Ltd. Freeze-dried preparation of n-¬o-(p-pivaloyloxybenzenesulfonylamino)benzoyl|glycine monosodium salt tetrahydrate and a process for the maufacture thereof
US20060074014A1 (en) 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
TWI342312B (en) * 2003-10-22 2011-05-21 Theravance Inc Hydrochloride salts of a glycopeptide phosphonate derivative
US8182461B2 (en) 2003-11-04 2012-05-22 Smiths Medical Asd, Inc. Syringe pump rapid occlusion detection system
JP5280813B2 (ja) * 2007-11-28 2013-09-04 日医工株式会社 グリコペプチド類含有凍結乾燥組成物及びその製造方法
KR101101663B1 (ko) * 2009-01-13 2011-12-30 (주) 제노텍 반코마이신 습체의 정제방법
WO2014194296A1 (en) * 2013-05-30 2014-12-04 Scidose, Llc Formulations of vancomycin
US10376559B2 (en) 2016-01-15 2019-08-13 Scidose, Llc Formulations of vancomycin
MX2018013584A (es) 2016-05-09 2019-04-01 Xellia Pharmaceuticals Aps Formulaciones de antibioticos glicopeptidicos estabilizados.
US20220133844A1 (en) 2020-10-30 2022-05-05 Somerset Therapeutics, Llc Glycopeptide antibiotics liquid formulations and methods and uses thereof
CN112691083B (zh) * 2020-12-28 2022-05-06 瀚晖制药有限公司 盐酸万古霉素的冻干工艺
WO2024092091A1 (en) * 2022-10-26 2024-05-02 Thomas Jefferson University Biodegradable pocket for drug delivery and associated methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3067099A (en) * 1955-09-16 1962-12-04 Lilly Co Eli Vancomycin and method for its preparation
HU176215B (en) * 1978-01-27 1981-01-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing a cyclodextrin-indomethacin inclusion complex with a ratio of at about 2:1
US4378348A (en) * 1979-12-28 1983-03-29 Otsuka Pharmaceutical Co., Ltd. OA-7653 Substance
JPS58177949A (ja) * 1982-04-12 1983-10-18 Takeda Chem Ind Ltd ランカシジン群抗生物質包接化合物
US4670258A (en) * 1984-02-10 1987-06-02 Vanderbilt University Storable prepackaged aqueous solutions of vancomycin
US4547488A (en) * 1984-04-16 1985-10-15 Eli Lilly And Company Antibiotic M43D, pharmaceutical compositions and method of use
AU618517B2 (en) * 1986-12-23 1992-01-02 Eugene J. Van Scott Additives enhancing topical actions of therapeutic agents

Also Published As

Publication number Publication date
ATE74013T1 (de) 1992-04-15
JP2983934B2 (ja) 1999-11-29
EP0318146A1 (en) 1989-05-31
ES2036690T3 (es) 1993-06-01
JPH01146825A (ja) 1989-06-08
JP2883890B2 (ja) 1999-04-19
IL88024A0 (en) 1989-06-30
HUT49285A (en) 1989-09-28
EP0318146B1 (en) 1992-03-25
JPH1081619A (ja) 1998-03-31
CA1326211C (en) 1994-01-18
AU2369688A (en) 1989-06-08
IE61049B1 (en) 1994-09-21
AU610936B2 (en) 1991-05-30
HU200558B (en) 1990-07-28
GR3004155T3 (ko) 1993-03-31
IE883129L (en) 1989-04-15
US4885275A (en) 1989-12-05
DK570588A (da) 1989-04-16
DE3869563D1 (de) 1992-04-30
ZA887579B (en) 1990-06-27
KR970007907B1 (ko) 1997-05-17
PH25109A (en) 1991-02-19
DK570588D0 (da) 1988-10-13
KR890006243A (ko) 1989-06-12
IL88024A (en) 1993-04-04
NZ226550A (en) 1990-04-26

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Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired