IL88024A - Aqueous gel-free formulation of vancomycin hydrochloride and its preparation - Google Patents

Aqueous gel-free formulation of vancomycin hydrochloride and its preparation

Info

Publication number
IL88024A
IL88024A IL88024A IL8802488A IL88024A IL 88024 A IL88024 A IL 88024A IL 88024 A IL88024 A IL 88024A IL 8802488 A IL8802488 A IL 8802488A IL 88024 A IL88024 A IL 88024A
Authority
IL
Israel
Prior art keywords
vancomycin hydrochloride
preparation
gel
aqueous gel
free formulation
Prior art date
Application number
IL88024A
Other languages
English (en)
Other versions
IL88024A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22330088&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL88024(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL88024A0 publication Critical patent/IL88024A0/xx
Publication of IL88024A publication Critical patent/IL88024A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
IL88024A 1987-10-15 1988-10-12 Aqueous gel-free formulation of vancomycin hydrochloride and its preparation IL88024A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/109,885 US4885275A (en) 1987-10-15 1987-10-15 Vancomycin-HCL solutions and the lyophilization thereof

Publications (2)

Publication Number Publication Date
IL88024A0 IL88024A0 (en) 1989-06-30
IL88024A true IL88024A (en) 1993-04-04

Family

ID=22330088

Family Applications (1)

Application Number Title Priority Date Filing Date
IL88024A IL88024A (en) 1987-10-15 1988-10-12 Aqueous gel-free formulation of vancomycin hydrochloride and its preparation

Country Status (17)

Country Link
US (1) US4885275A (xx)
EP (1) EP0318146B1 (xx)
JP (2) JP2883890B2 (xx)
KR (1) KR970007907B1 (xx)
AT (1) ATE74013T1 (xx)
AU (1) AU610936B2 (xx)
CA (1) CA1326211C (xx)
DE (1) DE3869563D1 (xx)
DK (1) DK167141B1 (xx)
ES (1) ES2036690T3 (xx)
GR (1) GR3004155T3 (xx)
HU (1) HU200558B (xx)
IE (1) IE61049B1 (xx)
IL (1) IL88024A (xx)
NZ (1) NZ226550A (xx)
PH (1) PH25109A (xx)
ZA (1) ZA887579B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03193735A (ja) * 1989-12-22 1991-08-23 Shionogi & Co Ltd グリコペプチド系抗生物質の安定化組成物
CA2238872A1 (en) * 1995-12-01 1997-06-05 Eli Lilly And Company Stable vancomycin hydrochloride solutions
US5786022A (en) * 1996-10-31 1998-07-28 Ethicon, Inc. Coating mixture for surgical articles
US6391851B1 (en) * 1997-03-10 2002-05-21 Fujisawa Pharmaceutical Co., Ltd. Hydrochlorides of vancomycin antibiotics and process for producing the same
JP3875023B2 (ja) * 1998-02-13 2007-01-31 コリア リサーチ インスティチュート オブ ケミカル テクノロジイ コアー殻触媒相の固形触媒とその製造方法
UA75083C2 (uk) * 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
CA2416600A1 (en) * 2000-07-24 2003-01-20 Ono Pharmaceutical Co., Ltd. Freeze-dried preparation of n-¬o-(p-pivaloyloxybenzenesulfonylamino)benzoyl|glycine monosodium salt tetrahydrate and a process for the maufacture thereof
US20060074014A1 (en) 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
TWI342312B (en) * 2003-10-22 2011-05-21 Theravance Inc Hydrochloride salts of a glycopeptide phosphonate derivative
US8182461B2 (en) 2003-11-04 2012-05-22 Smiths Medical Asd, Inc. Syringe pump rapid occlusion detection system
JP5280813B2 (ja) * 2007-11-28 2013-09-04 日医工株式会社 グリコペプチド類含有凍結乾燥組成物及びその製造方法
KR101101663B1 (ko) * 2009-01-13 2011-12-30 (주) 제노텍 반코마이신 습체의 정제방법
WO2014194296A1 (en) * 2013-05-30 2014-12-04 Scidose, Llc Formulations of vancomycin
EP3402463B1 (en) 2016-01-15 2021-04-14 SciDose Pharma LLC Formulations of vancomycin
US10729708B2 (en) 2016-05-09 2020-08-04 Xellia Pharmaceuticals Aps Stabilized glycopeptide antibiotic formulations
US11433115B2 (en) 2020-10-30 2022-09-06 Somerset Therapeutics, Llc Glycopeptide antibiotics liquid formulations and methods and uses thereof
CN112691083B (zh) * 2020-12-28 2022-05-06 瀚晖制药有限公司 盐酸万古霉素的冻干工艺
WO2024092091A1 (en) * 2022-10-26 2024-05-02 Thomas Jefferson University Biodegradable pocket for drug delivery and associated methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3067099A (en) * 1955-09-16 1962-12-04 Lilly Co Eli Vancomycin and method for its preparation
HU176215B (en) * 1978-01-27 1981-01-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing a cyclodextrin-indomethacin inclusion complex with a ratio of at about 2:1
US4378348A (en) * 1979-12-28 1983-03-29 Otsuka Pharmaceutical Co., Ltd. OA-7653 Substance
JPS58177949A (ja) * 1982-04-12 1983-10-18 Takeda Chem Ind Ltd ランカシジン群抗生物質包接化合物
US4670258A (en) * 1984-02-10 1987-06-02 Vanderbilt University Storable prepackaged aqueous solutions of vancomycin
US4547488A (en) * 1984-04-16 1985-10-15 Eli Lilly And Company Antibiotic M43D, pharmaceutical compositions and method of use
AU618517B2 (en) * 1986-12-23 1992-01-02 Eugene J. Van Scott Additives enhancing topical actions of therapeutic agents

Also Published As

Publication number Publication date
JP2883890B2 (ja) 1999-04-19
GR3004155T3 (xx) 1993-03-31
IE883129L (en) 1989-04-15
US4885275A (en) 1989-12-05
ZA887579B (en) 1990-06-27
DK570588A (da) 1989-04-16
EP0318146B1 (en) 1992-03-25
DK167141B1 (da) 1993-09-06
HUT49285A (en) 1989-09-28
AU610936B2 (en) 1991-05-30
HU200558B (en) 1990-07-28
KR970007907B1 (ko) 1997-05-17
AU2369688A (en) 1989-06-08
IE61049B1 (en) 1994-09-21
ES2036690T3 (es) 1993-06-01
CA1326211C (en) 1994-01-18
ATE74013T1 (de) 1992-04-15
EP0318146A1 (en) 1989-05-31
PH25109A (en) 1991-02-19
JP2983934B2 (ja) 1999-11-29
KR890006243A (ko) 1989-06-12
IL88024A0 (en) 1989-06-30
DK570588D0 (da) 1988-10-13
JPH1081619A (ja) 1998-03-31
JPH01146825A (ja) 1989-06-08
NZ226550A (en) 1990-04-26
DE3869563D1 (de) 1992-04-30

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