DK166879B1 - Phenoxyeddikesyrederivater samt fremgangsmaader til fremstilling deraf og farmaceutiske praeparater indeholdende forbindelserne - Google Patents

Phenoxyeddikesyrederivater samt fremgangsmaader til fremstilling deraf og farmaceutiske praeparater indeholdende forbindelserne Download PDF

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Publication number
DK166879B1
DK166879B1 DK532987A DK532987A DK166879B1 DK 166879 B1 DK166879 B1 DK 166879B1 DK 532987 A DK532987 A DK 532987A DK 532987 A DK532987 A DK 532987A DK 166879 B1 DK166879 B1 DK 166879B1
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DK
Denmark
Prior art keywords
compound
formula
pyrazolyl
dichloro
salt
Prior art date
Application number
DK532987A
Other languages
Danish (da)
English (en)
Other versions
DK532987D0 (da
DK532987A (da
Inventor
Norio Takamura
Kuniyuki Oda
Shinichi Kodato
Isao Yamaguchi
Koji Yano
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of DK532987D0 publication Critical patent/DK532987D0/da
Publication of DK532987A publication Critical patent/DK532987A/da
Application granted granted Critical
Publication of DK166879B1 publication Critical patent/DK166879B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK532987A 1986-10-13 1987-10-12 Phenoxyeddikesyrederivater samt fremgangsmaader til fremstilling deraf og farmaceutiske praeparater indeholdende forbindelserne DK166879B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24280286 1986-10-13
JP24280286 1986-10-13

Publications (3)

Publication Number Publication Date
DK532987D0 DK532987D0 (da) 1987-10-12
DK532987A DK532987A (da) 1988-04-14
DK166879B1 true DK166879B1 (da) 1993-07-26

Family

ID=17094503

Family Applications (1)

Application Number Title Priority Date Filing Date
DK532987A DK166879B1 (da) 1986-10-13 1987-10-12 Phenoxyeddikesyrederivater samt fremgangsmaader til fremstilling deraf og farmaceutiske praeparater indeholdende forbindelserne

Country Status (17)

Country Link
US (1) US4853404A (zh)
EP (1) EP0268800B1 (zh)
JP (1) JPS63225359A (zh)
KR (1) KR920002296B1 (zh)
CN (1) CN1014787B (zh)
AT (1) ATE72429T1 (zh)
AU (1) AU595385B2 (zh)
CA (1) CA1311483C (zh)
DE (1) DE3776627D1 (zh)
DK (1) DK166879B1 (zh)
ES (1) ES2032284T3 (zh)
FI (1) FI91402C (zh)
GR (1) GR3003727T3 (zh)
HK (1) HK47193A (zh)
HU (1) HU202501B (zh)
IE (1) IE60044B1 (zh)
IL (1) IL84106A (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2613720B1 (fr) * 1987-04-10 1990-01-19 Esteve Labor Dr Derives d'aryl-heteroaryl carbinols avec activite analgesique
JPH01316317A (ja) * 1988-03-10 1989-12-21 Tanabe Seiyaku Co Ltd 降圧剤
CA2036192A1 (en) 1990-02-13 1991-08-14 Nicholas Meanwell Heterocyclic carboxylic acids and esters
US4956379A (en) * 1990-02-13 1990-09-11 Bristol-Myers Squibb Company Pyrazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith
US20040067531A1 (en) * 1997-08-20 2004-04-08 Sugen, Inc. Methods of modulating protein tyrosine kinase function with substituted indolinone compounds
EA005996B1 (ru) 2000-02-15 2005-08-25 Сьюджен, Инк. Пирролзамещенный 2-индолинон, фармацевтическая композиция (варианты), способ модулирования каталитической активности протеинкиназы, способ лечения или профилактики нарушения в организме, связанного с протеинкиназой
AR042586A1 (es) * 2001-02-15 2005-06-29 Sugen Inc 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
BR0213185A (pt) 2001-10-10 2004-09-14 Sugen Inc Derivados de 3-[4-(heterociclila substituìda)-pirrol-2-ilmetilideno]2-indolinona como inibidores de cinase

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342851A (en) * 1964-10-30 1967-09-19 Merck & Co Inc Esters of [(2-methyleneacyl)phenoxy]-carboxylic acids and a method for their preparation
CH543472A (fr) * 1969-01-31 1973-10-31 Orchimed Sa Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques
GB1415295A (en) * 1971-10-14 1975-11-26 Orchimed Sa Substituted phenoxy-alkyl-carboxylic acids and derivatives thereof
US4107179A (en) * 1977-08-22 1978-08-15 Smithkline Corporation Method for preparing ticrynafen
GB2025942A (en) * 1978-05-31 1980-01-30 Sori Soc Rech Ind Phenoxyalkylcarboxylic acids
US4323691A (en) * 1979-10-09 1982-04-06 Abbott Laboratories Hydroxyaminomethyl derivatives of benzoyl di-substituted α-phenoxyalkanoyl esters

Also Published As

Publication number Publication date
FI874473A0 (fi) 1987-10-12
IL84106A0 (en) 1988-03-31
CN87106895A (zh) 1988-04-20
IE872668L (en) 1988-04-13
HUT50788A (en) 1990-03-28
FI91402C (fi) 1994-06-27
US4853404A (en) 1989-08-01
HU202501B (en) 1991-03-28
DE3776627D1 (de) 1992-03-19
FI874473A (fi) 1988-04-14
DK532987D0 (da) 1987-10-12
AU7956387A (en) 1988-04-14
FI91402B (fi) 1994-03-15
IL84106A (en) 1991-07-18
ES2032284T3 (es) 1993-02-01
HK47193A (en) 1993-05-21
AU595385B2 (en) 1990-03-29
KR920002296B1 (ko) 1992-03-21
ATE72429T1 (de) 1992-02-15
JPH0544944B2 (zh) 1993-07-07
KR880005089A (ko) 1988-06-28
JPS63225359A (ja) 1988-09-20
GR3003727T3 (zh) 1993-03-16
CA1311483C (en) 1992-12-15
CN1014787B (zh) 1991-11-20
DK532987A (da) 1988-04-14
EP0268800A1 (en) 1988-06-01
IE60044B1 (en) 1994-05-18
EP0268800B1 (en) 1992-02-05

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