DK1666026T4 - Ikke-vandige enkelt-fase biokompatible, viskøse fremføringsmidler og fremgangsmåder til fremstilling deraf - Google Patents

Ikke-vandige enkelt-fase biokompatible, viskøse fremføringsmidler og fremgangsmåder til fremstilling deraf Download PDF

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Publication number
DK1666026T4
DK1666026T4 DK06075430T DK06075430T DK1666026T4 DK 1666026 T4 DK1666026 T4 DK 1666026T4 DK 06075430 T DK06075430 T DK 06075430T DK 06075430 T DK06075430 T DK 06075430T DK 1666026 T4 DK1666026 T4 DK 1666026T4
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DK
Denmark
Prior art keywords
feeders
viscous
processes
preparation
aqueous single
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Application number
DK06075430T
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Danish (da)
English (en)
Other versions
DK1666026T3 (da
Inventor
Stephan Berry
Houdin Dehnad
Anna Muchnik
Pamela J Fereira
Original Assignee
Intarcia Therapeutics Inc
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Application filed by Intarcia Therapeutics Inc filed Critical Intarcia Therapeutics Inc
Publication of DK1666026T3 publication Critical patent/DK1666026T3/da
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DK06075430T 1999-02-08 2000-02-02 Ikke-vandige enkelt-fase biokompatible, viskøse fremføringsmidler og fremgangsmåder til fremstilling deraf DK1666026T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11917099P 1999-02-08 1999-02-08
EP00913350A EP1152749B1 (en) 1999-02-08 2000-02-02 Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles

Publications (2)

Publication Number Publication Date
DK1666026T3 DK1666026T3 (da) 2012-04-10
DK1666026T4 true DK1666026T4 (da) 2015-05-04

Family

ID=22382917

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06075430T DK1666026T4 (da) 1999-02-08 2000-02-02 Ikke-vandige enkelt-fase biokompatible, viskøse fremføringsmidler og fremgangsmåder til fremstilling deraf

Country Status (22)

Country Link
EP (2) EP1666026B2 (https=)
JP (1) JP4861551B2 (https=)
KR (2) KR100858856B1 (https=)
CN (1) CN1232244C (https=)
AR (1) AR029613A1 (https=)
AT (2) ATE537811T1 (https=)
AU (1) AU775904B2 (https=)
CA (1) CA2361424C (https=)
CO (1) CO5140096A1 (https=)
CY (1) CY1119950T1 (https=)
DE (1) DE60027272T2 (https=)
DK (1) DK1666026T4 (https=)
ES (2) ES2379471T5 (https=)
HK (1) HK1041451B (https=)
HU (1) HUP0200202A3 (https=)
IL (1) IL144755A0 (https=)
NO (1) NO20013861L (https=)
NZ (1) NZ513441A (https=)
PT (2) PT1666026E (https=)
TW (2) TW200730199A (https=)
WO (1) WO2000045790A2 (https=)
ZA (1) ZA200106443B (https=)

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Publication number Publication date
NO20013861L (no) 2001-09-20
PT1666026E (pt) 2012-03-15
CA2361424C (en) 2009-04-28
KR100858856B1 (ko) 2008-09-17
EP1666026B2 (en) 2015-02-25
HUP0200202A2 (hu) 2002-05-29
ATE322889T1 (de) 2006-04-15
EP1666026A2 (en) 2006-06-07
CY1119950T1 (el) 2018-12-12
TWI292716B (en) 2008-01-21
ES2379471T3 (es) 2012-04-26
NZ513441A (en) 2004-01-30
DE60027272D1 (de) 2006-05-24
AU775904B2 (en) 2004-08-19
PT1152749E (pt) 2006-08-31
DK1666026T3 (da) 2012-04-10
CN1339962A (zh) 2002-03-13
CO5140096A1 (es) 2002-03-22
JP2002536315A (ja) 2002-10-29
KR20080045300A (ko) 2008-05-22
EP1666026A3 (en) 2007-08-08
ATE537811T1 (de) 2012-01-15
EP1152749B1 (en) 2006-04-12
EP1152749A2 (en) 2001-11-14
TW200730199A (en) 2007-08-16
AR029613A1 (es) 2003-07-10
JP4861551B2 (ja) 2012-01-25
CA2361424A1 (en) 2000-08-10
ZA200106443B (en) 2002-08-06
KR20010101842A (ko) 2001-11-14
EP1666026B1 (en) 2011-12-21
NO20013861D0 (no) 2001-08-08
WO2000045790A2 (en) 2000-08-10
HK1041451A1 (en) 2002-07-12
HK1041451B (en) 2006-12-01
HUP0200202A3 (en) 2009-08-28
HK1094528A1 (en) 2007-04-04
ES2261190T3 (es) 2006-11-16
CN1232244C (zh) 2005-12-21
IL144755A0 (en) 2002-06-30
AU3481600A (en) 2000-08-25
WO2000045790A3 (en) 2000-12-07
ES2379471T5 (es) 2015-05-26
DE60027272T2 (de) 2007-01-25

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