DK166282C - Fremgangsmaade til fremstilling af cephemforbindelser - Google Patents

Fremgangsmaade til fremstilling af cephemforbindelser

Info

Publication number
DK166282C
DK166282C DK224284A DK224284A DK166282C DK 166282 C DK166282 C DK 166282C DK 224284 A DK224284 A DK 224284A DK 224284 A DK224284 A DK 224284A DK 166282 C DK166282 C DK 166282C
Authority
DK
Denmark
Prior art keywords
cephem
relations
procedure
making
making cephem
Prior art date
Application number
DK224284A
Other languages
English (en)
Other versions
DK224284D0 (da
DK166282B (da
DK224284A (da
Inventor
Wilfried Schwab
Walter Duerckheimer
Reiner Kirrstetter
Rudolf Lattrell
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK224284D0 publication Critical patent/DK224284D0/da
Publication of DK224284A publication Critical patent/DK224284A/da
Publication of DK166282B publication Critical patent/DK166282B/da
Application granted granted Critical
Publication of DK166282C publication Critical patent/DK166282C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK224284A 1983-05-07 1984-05-04 Fremgangsmaade til fremstilling af cephemforbindelser DK166282C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3316798 1983-05-07
DE19833316798 DE3316798A1 (de) 1983-05-07 1983-05-07 Verfahren zur herstellung von cephemverbindungen

Publications (4)

Publication Number Publication Date
DK224284D0 DK224284D0 (da) 1984-05-04
DK224284A DK224284A (da) 1984-11-08
DK166282B DK166282B (da) 1993-03-29
DK166282C true DK166282C (da) 1993-08-23

Family

ID=6198462

Family Applications (1)

Application Number Title Priority Date Filing Date
DK224284A DK166282C (da) 1983-05-07 1984-05-04 Fremgangsmaade til fremstilling af cephemforbindelser

Country Status (24)

Country Link
US (1) US4667028A (da)
EP (1) EP0124889A3 (da)
JP (1) JPS6034972A (da)
KR (1) KR910004332B1 (da)
AU (1) AU575825B2 (da)
CA (1) CA1224457A (da)
CS (1) CS247081B2 (da)
DD (1) DD251133A5 (da)
DE (1) DE3316798A1 (da)
DK (1) DK166282C (da)
ES (1) ES8502445A1 (da)
FI (1) FI82055C (da)
HU (1) HU191683B (da)
IL (1) IL71771A (da)
MA (1) MA20110A1 (da)
MT (1) MTP947B (da)
MX (1) MX168599B (da)
NO (1) NO841792L (da)
NZ (1) NZ208064A (da)
OA (1) OA07766A (da)
PH (1) PH19554A (da)
PT (1) PT78544B (da)
YU (1) YU45965B (da)
ZA (1) ZA843343B (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60169486A (ja) * 1984-02-10 1985-09-02 Yamanouchi Pharmaceut Co Ltd ７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法
IL74822A (en) * 1984-04-17 1989-06-30 Daiichi Seiyaku Co Cephalosporin derivatives and salts thereof and their preparation
US4788185A (en) * 1984-04-23 1988-11-29 Takeda Chemical Industries, Ltd. Cephalosporin compounds
ATE121746T1 (de) * 1984-11-23 1995-05-15 Biochemie Gmbh Verfahren zur herstellung bissilylierter 3- iodmethylcephalosporinderivaten.
ATE89826T1 (de) * 1985-03-01 1993-06-15 Takeda Chemical Industries Ltd Antibakterielle verbindungen, ihre herstellung und verwendung.
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
GB8519606D0 (en) * 1985-08-05 1985-09-11 Fujisawa Pharmaceutical Co 3 7-d substituted-3-cephem compounds
US4714760A (en) * 1985-08-20 1987-12-22 Bristol-Myers Company Cephalosporin intermediates
US4749522A (en) * 1985-10-31 1988-06-07 Angio-Medical Corporation Supercritical fluid extraction of animal derived materials
DE3542644A1 (de) * 1985-12-03 1987-06-04 Hoechst Ag Verfahren zur herstellung von cefodizim
CA1296012C (en) * 1986-03-19 1992-02-18 Susumu Nakagawa 6,7-dihydroxy-isoquinoline derivatives
US4868294A (en) * 1986-07-11 1989-09-19 Bristol-Myers Company Process for preparing cephalosporin intermediates
DE3706020A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
TWI335332B (en) * 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
CN102002058B (zh) * 2010-11-05 2012-04-04 山东鲁抗立科药物化学有限公司 硫酸头孢喹肟的合成方法
EP2862569A1 (en) 2011-09-09 2015-04-22 Cubist Pharmaceuticals, Inc. Methods for treating intrapulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
KR102226197B1 (ko) 2013-03-15 2021-03-11 머크 샤프 앤드 돔 코포레이션 세프톨로잔 항균성 조성물
US9320740B2 (en) 2013-03-15 2016-04-26 Merck Sharp & Dohme Corp. Ceftolozane-tazobactam pharmaceutical compositions
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane
CN103601738A (zh) * 2013-12-04 2014-02-26 哈药集团制药总厂 一种头孢匹罗氢碘酸盐的制备方法
CN105646543B (zh) * 2016-03-17 2018-03-27 天津大学 一种头孢喹肟晶体及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
US4266049A (en) * 1980-02-20 1981-05-05 Eli Lilly And Company Process for 3-iodomethyl cephalosporins
US4367228A (en) * 1980-10-29 1983-01-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compound and composition
US4336253A (en) * 1981-03-11 1982-06-22 Eli Lilly And Company Cephalosporin antibiotics
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
ZA825095B (en) * 1981-07-17 1983-05-25 Glaxo Group Ltd Cephalosporin compounds
US4396619A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin betaines
ZA826538B (en) * 1981-09-08 1984-04-25 Lilly Co Eli Thieno and furopyridinium-substituted cephalosporin derivatives
US4396620A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin quinolinium betaines
US4402955A (en) * 1981-10-02 1983-09-06 Eli Lilly And Company Dioximino cephalosporin antibiotics

Also Published As

Publication number Publication date
MX168599B (es) 1993-06-01
PH19554A (en) 1986-05-21
MA20110A1 (fr) 1984-12-31
FI82055C (fi) 1991-01-10
ES532183A0 (es) 1985-01-01
ES8502445A1 (es) 1985-01-01
YU45965B (sh) 1992-12-21
NO841792L (no) 1984-11-08
IL71771A (en) 1988-06-30
YU76684A (en) 1986-10-31
EP0124889A3 (de) 1985-11-27
MTP947B (en) 1985-01-17
US4667028A (en) 1987-05-19
NZ208064A (en) 1987-07-31
CS247081B2 (en) 1986-11-13
AU2770584A (en) 1984-11-08
AU575825B2 (en) 1988-08-11
CA1224457A (en) 1987-07-21
KR840009116A (ko) 1984-12-24
FI82055B (fi) 1990-09-28
DE3316798A1 (de) 1984-11-08
DK224284D0 (da) 1984-05-04
DK166282B (da) 1993-03-29
DD251133A5 (de) 1987-11-04
HU191683B (en) 1987-03-30
IL71771A0 (en) 1984-09-30
EP0124889A2 (de) 1984-11-14
FI841764A (fi) 1984-11-08
PT78544B (de) 1986-07-17
KR910004332B1 (ko) 1991-06-26
ZA843343B (en) 1984-12-24
JPS6034972A (ja) 1985-02-22
PT78544A (de) 1984-06-01
FI841764A0 (fi) 1984-05-03
DK224284A (da) 1984-11-08
HUT34506A (en) 1985-03-28
OA07766A (fr) 1985-08-30

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