IL71771A - Process for the preparation of 7-(2-(aminothiazolyl or aminothiadiazolyl)2-hydroxyiminoacetamido)-3-(ammoniomethyl)-ceph-3-em-4-carboxylate derivatives - Google Patents

Process for the preparation of 7-(2-(aminothiazolyl or aminothiadiazolyl)2-hydroxyiminoacetamido)-3-(ammoniomethyl)-ceph-3-em-4-carboxylate derivatives

Info

Publication number
IL71771A
IL71771A IL71771A IL7177184A IL71771A IL 71771 A IL71771 A IL 71771A IL 71771 A IL71771 A IL 71771A IL 7177184 A IL7177184 A IL 7177184A IL 71771 A IL71771 A IL 71771A
Authority
IL
Israel
Prior art keywords
ammoniomethyl
aminothiadiazolyl
hydroxyiminoacetamido
aminothiazolyl
ceph
Prior art date
Application number
IL71771A
Other languages
English (en)
Other versions
IL71771A0 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL71771A0 publication Critical patent/IL71771A0/xx
Publication of IL71771A publication Critical patent/IL71771A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL71771A 1983-05-07 1984-05-06 Process for the preparation of 7-(2-(aminothiazolyl or aminothiadiazolyl)2-hydroxyiminoacetamido)-3-(ammoniomethyl)-ceph-3-em-4-carboxylate derivatives IL71771A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833316798 DE3316798A1 (de) 1983-05-07 1983-05-07 Verfahren zur herstellung von cephemverbindungen

Publications (2)

Publication Number Publication Date
IL71771A0 IL71771A0 (en) 1984-09-30
IL71771A true IL71771A (en) 1988-06-30

Family

ID=6198462

Family Applications (1)

Application Number Title Priority Date Filing Date
IL71771A IL71771A (en) 1983-05-07 1984-05-06 Process for the preparation of 7-(2-(aminothiazolyl or aminothiadiazolyl)2-hydroxyiminoacetamido)-3-(ammoniomethyl)-ceph-3-em-4-carboxylate derivatives

Country Status (24)

Country Link
US (1) US4667028A (da)
EP (1) EP0124889A3 (da)
JP (1) JPS6034972A (da)
KR (1) KR910004332B1 (da)
AU (1) AU575825B2 (da)
CA (1) CA1224457A (da)
CS (1) CS247081B2 (da)
DD (1) DD251133A5 (da)
DE (1) DE3316798A1 (da)
DK (1) DK166282C (da)
ES (1) ES532183A0 (da)
FI (1) FI82055C (da)
HU (1) HU191683B (da)
IL (1) IL71771A (da)
MA (1) MA20110A1 (da)
MT (1) MTP947B (da)
MX (1) MX168599B (da)
NO (1) NO841792L (da)
NZ (1) NZ208064A (da)
OA (1) OA07766A (da)
PH (1) PH19554A (da)
PT (1) PT78544B (da)
YU (1) YU45965B (da)
ZA (1) ZA843343B (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60169486A (ja) * 1984-02-10 1985-09-02 Yamanouchi Pharmaceut Co Ltd ７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法
IL74822A (en) * 1984-04-17 1989-06-30 Daiichi Seiyaku Co Cephalosporin derivatives and salts thereof and their preparation
US4788185A (en) * 1984-04-23 1988-11-29 Takeda Chemical Industries, Ltd. Cephalosporin compounds
ATE177104T1 (de) * 1984-11-23 1999-03-15 Biochemie Gmbh Cephalosporinderivative
ATE89826T1 (de) * 1985-03-01 1993-06-15 Takeda Chemical Industries Ltd Antibakterielle verbindungen, ihre herstellung und verwendung.
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
GB8519606D0 (en) * 1985-08-05 1985-09-11 Fujisawa Pharmaceutical Co 3 7-d substituted-3-cephem compounds
US4714760A (en) * 1985-08-20 1987-12-22 Bristol-Myers Company Cephalosporin intermediates
US4749522A (en) * 1985-10-31 1988-06-07 Angio-Medical Corporation Supercritical fluid extraction of animal derived materials
DE3542644A1 (de) * 1985-12-03 1987-06-04 Hoechst Ag Verfahren zur herstellung von cefodizim
EP0238060B1 (en) * 1986-03-19 1992-01-08 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, processes for their preparation and antibacterial agents
US4868294A (en) * 1986-07-11 1989-09-19 Bristol-Myers Company Process for preparing cephalosporin intermediates
DE3706020A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
TWI335332B (en) 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
CN102002058B (zh) * 2010-11-05 2012-04-04 山东鲁抗立科药物化学有限公司 硫酸头孢喹肟的合成方法
HK1200096A1 (en) 2011-09-09 2015-07-31 Merck Sharp & Dohme Corp. Methods for treating intrapulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US20140274994A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Stabilizing ceftolozane
US20140274993A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane-tazobactam pharmaceutical compositions
US10376496B2 (en) 2013-09-09 2019-08-13 Merck, Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane
CN103601738A (zh) * 2013-12-04 2014-02-26 哈药集团制药总厂 一种头孢匹罗氢碘酸盐的制备方法
CN105646543B (zh) * 2016-03-17 2018-03-27 天津大学 一种头孢喹肟晶体及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR229883A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
US4266049A (en) * 1980-02-20 1981-05-05 Eli Lilly And Company Process for 3-iodomethyl cephalosporins
US4367228A (en) * 1980-10-29 1983-01-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compound and composition
US4336253A (en) * 1981-03-11 1982-06-22 Eli Lilly And Company Cephalosporin antibiotics
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
ATE31535T1 (de) * 1981-07-17 1988-01-15 Glaxo Group Ltd Cephalosporinverbindungen.
ZA826538B (en) * 1981-09-08 1984-04-25 Lilly Co Eli Thieno and furopyridinium-substituted cephalosporin derivatives
US4396620A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin quinolinium betaines
US4396619A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin betaines
US4402955A (en) * 1981-10-02 1983-09-06 Eli Lilly And Company Dioximino cephalosporin antibiotics

Also Published As

Publication number Publication date
HU191683B (en) 1987-03-30
YU76684A (en) 1986-10-31
DK224284A (da) 1984-11-08
PT78544B (de) 1986-07-17
OA07766A (fr) 1985-08-30
ES8502445A1 (es) 1985-01-01
IL71771A0 (en) 1984-09-30
PH19554A (en) 1986-05-21
PT78544A (de) 1984-06-01
AU575825B2 (en) 1988-08-11
ES532183A0 (es) 1985-01-01
MA20110A1 (fr) 1984-12-31
AU2770584A (en) 1984-11-08
DE3316798A1 (de) 1984-11-08
DK166282C (da) 1993-08-23
DK166282B (da) 1993-03-29
ZA843343B (en) 1984-12-24
FI841764A7 (fi) 1984-11-08
MTP947B (en) 1985-01-17
NO841792L (no) 1984-11-08
KR840009116A (ko) 1984-12-24
KR910004332B1 (ko) 1991-06-26
EP0124889A3 (de) 1985-11-27
NZ208064A (en) 1987-07-31
YU45965B (sh) 1992-12-21
HUT34506A (en) 1985-03-28
CS247081B2 (en) 1986-11-13
DD251133A5 (de) 1987-11-04
EP0124889A2 (de) 1984-11-14
MX168599B (es) 1993-06-01
US4667028A (en) 1987-05-19
FI841764A0 (fi) 1984-05-03
FI82055B (fi) 1990-09-28
CA1224457A (en) 1987-07-21
DK224284D0 (da) 1984-05-04
JPS6034972A (ja) 1985-02-22
FI82055C (fi) 1991-01-10

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