DK166211C - Krystalliseret cephem-syreadditionssalt, dets fremstilling og anvendelse - Google Patents
Krystalliseret cephem-syreadditionssalt, dets fremstilling og anvendelseInfo
- Publication number
- DK166211C DK166211C DK600183A DK600183A DK166211C DK 166211 C DK166211 C DK 166211C DK 600183 A DK600183 A DK 600183A DK 600183 A DK600183 A DK 600183A DK 166211 C DK166211 C DK 166211C
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- application
- acid addition
- addition salt
- crystallized
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000001782 cephems Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3248281 | 1982-12-28 | ||
| DE19823248281 DE3248281A1 (de) | 1982-12-28 | 1982-12-28 | Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK600183D0 DK600183D0 (da) | 1983-12-27 |
| DK600183A DK600183A (da) | 1984-06-29 |
| DK166211B DK166211B (da) | 1993-03-22 |
| DK166211C true DK166211C (da) | 1993-08-16 |
Family
ID=6181953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK600183A DK166211C (da) | 1982-12-28 | 1983-12-27 | Krystalliseret cephem-syreadditionssalt, dets fremstilling og anvendelse |
Country Status (28)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3118732A1 (de) * | 1981-05-12 | 1982-12-02 | Hoechst Ag, 6000 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
| EP0150507B1 (en) * | 1983-12-29 | 1992-08-05 | Mochida Pharmaceutical Co., Ltd. | Cephalosporin derivatives, processes for producing the same and compositions containing them |
| JPS60142987A (ja) * | 1983-12-29 | 1985-07-29 | Mochida Pharmaceut Co Ltd | セフアロスポリン誘導体 |
| JPS60169486A (ja) * | 1984-02-10 | 1985-09-02 | Yamanouchi Pharmaceut Co Ltd | ７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法 |
| JPH0649707B2 (ja) * | 1985-03-01 | 1994-06-29 | 第一製薬株式会社 | ３−ピリジニウムメチルセフエム誘導体 |
| US4840945A (en) * | 1985-04-01 | 1989-06-20 | Mochida Pharmaceutical Co., Ltd. | Cephalosporin derivatives |
| US5244891A (en) * | 1985-08-05 | 1993-09-14 | Bristol-Myers Squibb Company | Injectable compositions of cefepime dihydrochloride hydrate |
| US4880798A (en) * | 1986-11-25 | 1989-11-14 | Mochida Pharmaceutical Co., Ltd. | Cephalosporin derivatives |
| JPS63132893A (ja) * | 1986-11-25 | 1988-06-04 | Mochida Pharmaceut Co Ltd | 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤 |
| DE3706020A1 (de) * | 1987-02-25 | 1988-09-08 | Hoechst Ag | Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung |
| DE4440141A1 (de) * | 1994-11-10 | 1996-05-15 | Hoechst Ag | Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung |
| TW526202B (en) | 1998-11-27 | 2003-04-01 | Shionogi & Amp Co | Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity |
| DE60205882D1 (de) * | 2001-04-23 | 2005-10-06 | Shionogi & Co | Sulfat von cephemverbindung |
| WO2004039816A1 (ja) * | 2002-10-29 | 2004-05-13 | Shionogi & Co., Ltd. | セフェム化合物の無機酸塩の結晶 |
| CN101172982B (zh) * | 2006-11-03 | 2011-06-08 | 河北凯盛医药科技有限公司 | 一种硫酸头孢匹罗的制备方法 |
| WO2008056221A2 (en) * | 2006-11-06 | 2008-05-15 | Orchid Chemicals & Pharmaceuticals Limited | Crystalline sulfate salt of cephalosporin antibiotic |
| CN101104621A (zh) * | 2007-05-08 | 2008-01-16 | 深圳信立泰药业股份有限公司 | 制备高纯度硫酸头孢匹罗的工艺 |
| CN101284840B (zh) * | 2008-05-29 | 2012-07-04 | 管小明 | 硫酸头孢匹罗的合成方法 |
| CN103044455B (zh) * | 2011-10-17 | 2015-04-01 | 苏州中联化学制药有限公司 | 硫酸头孢匹罗混粉的返工方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS523091A (en) * | 1975-06-23 | 1977-01-11 | Takeda Chem Ind Ltd | A prcess for preparing cephalosporins |
| DE3019838A1 (de) * | 1979-05-25 | 1980-12-04 | Glaxo Group Ltd | Zwischenprodukte zur verwendung bei der herstellung von cephalosporin-antibiotika |
| AU540382B2 (en) * | 1979-10-02 | 1984-11-15 | Glaxo Group Limited | 7(2-(2-aminothiazol-4-yl)-2-(2-carboxy prop-2-oxyimino) acetamido)-3-(1-pyridiniummethyl) ceph-3-em-4-carboxylate |
| EP0062321B1 (en) * | 1981-04-03 | 1989-03-01 | Fujisawa Pharmaceutical Co., Ltd. | New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds |
| DE3118732A1 (de) * | 1981-05-12 | 1982-12-02 | Hoechst Ag, 6000 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
-
1982
- 1982-12-28 DE DE19823248281 patent/DE3248281A1/de not_active Withdrawn
-
1983
- 1983-12-21 HU HU834391A patent/HU191385B/hu unknown
- 1983-12-21 AT AT83112862T patent/ATE50261T1/de not_active IP Right Cessation
- 1983-12-21 EP EP83112862A patent/EP0112550B1/de not_active Expired - Lifetime
- 1983-12-21 DE DE8383112862T patent/DE3381201D1/de not_active Expired - Lifetime
- 1983-12-22 NZ NZ206704A patent/NZ206704A/xx unknown
- 1983-12-22 IE IE3045/83A patent/IE56488B1/en not_active IP Right Cessation
- 1983-12-23 AU AU22893/83A patent/AU562714B2/en not_active Expired
- 1983-12-23 CA CA000444281A patent/CA1235690A/en not_active Expired
- 1983-12-23 FI FI834771A patent/FI76094C/fi not_active IP Right Cessation
- 1983-12-26 SU SU833680600A patent/SU1292668A3/ru active
- 1983-12-26 ES ES528401A patent/ES8407495A1/es not_active Expired
- 1983-12-26 IL IL70544A patent/IL70544A/xx not_active IP Right Cessation
- 1983-12-26 KR KR1019830006181A patent/KR910000420B1/ko not_active Expired
- 1983-12-26 YU YU2511/83A patent/YU43200B/xx unknown
- 1983-12-26 AR AR83295233A patent/AR245133A1/es active
- 1983-12-27 US US06/565,867 patent/US4609653A/en not_active Expired - Lifetime
- 1983-12-27 ZA ZA839593A patent/ZA839593B/xx unknown
- 1983-12-27 DK DK600183A patent/DK166211C/da not_active IP Right Cessation
- 1983-12-27 NO NO834824A patent/NO834824L/no unknown
- 1983-12-27 CS CS839974A patent/CS241070B2/cs unknown
- 1983-12-27 PT PT77896A patent/PT77896B/pt unknown
- 1983-12-27 PH PH30034A patent/PH19269A/en unknown
- 1983-12-27 MA MA20211A patent/MA19990A1/fr unknown
- 1983-12-27 DD DD83258690A patent/DD215552A5/de unknown
- 1983-12-27 GR GR73352A patent/GR79444B/el unknown
- 1983-12-28 OA OA58195A patent/OA07622A/xx unknown
- 1983-12-28 JP JP58252285A patent/JPH0723382B2/ja not_active Expired - Lifetime
- 1983-12-28 DZ DZ837035A patent/DZ592A1/fr active
-
1991
- 1991-12-30 CS CS914157A patent/CS415791A3/cs unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |