DK166084C - Imidazoquinolinyletherderivater og fremgangsmaade til deres fremstilling - Google Patents

Imidazoquinolinyletherderivater og fremgangsmaade til deres fremstilling

Info

Publication number
DK166084C
DK166084C DK263587A DK263587A DK166084C DK 166084 C DK166084 C DK 166084C DK 263587 A DK263587 A DK 263587A DK 263587 A DK263587 A DK 263587A DK 166084 C DK166084 C DK 166084C
Authority
DK
Denmark
Prior art keywords
imidazoquinolinylether
procedures
derivatives
preparation
imidazoquinolinylether derivatives
Prior art date
Application number
DK263587A
Other languages
Danish (da)
English (en)
Other versions
DK166084B (da
DK263587A (da
DK263587D0 (da
Inventor
Nicholas A Meanwell
John J Wright
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of DK263587D0 publication Critical patent/DK263587D0/da
Publication of DK263587A publication Critical patent/DK263587A/da
Publication of DK166084B publication Critical patent/DK166084B/da
Application granted granted Critical
Publication of DK166084C publication Critical patent/DK166084C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
DK263587A 1986-05-23 1987-05-22 Imidazoquinolinyletherderivater og fremgangsmaade til deres fremstilling DK166084C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86681386 1986-05-23
US06/866,813 US4775674A (en) 1986-05-23 1986-05-23 Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors

Publications (4)

Publication Number Publication Date
DK263587D0 DK263587D0 (da) 1987-05-22
DK263587A DK263587A (da) 1987-11-24
DK166084B DK166084B (da) 1993-03-08
DK166084C true DK166084C (da) 1993-08-02

Family

ID=25348473

Family Applications (1)

Application Number Title Priority Date Filing Date
DK263587A DK166084C (da) 1986-05-23 1987-05-22 Imidazoquinolinyletherderivater og fremgangsmaade til deres fremstilling

Country Status (24)

Country Link
US (1) US4775674A (de)
JP (1) JPS62283972A (de)
KR (1) KR900008567B1 (de)
AT (1) AT392790B (de)
AU (1) AU603577B2 (de)
BE (1) BE1002033A4 (de)
CA (1) CA1289137C (de)
CH (1) CH675246A5 (de)
DE (1) DE3717291A1 (de)
DK (1) DK166084C (de)
ES (1) ES2005588A6 (de)
FI (1) FI86723C (de)
FR (1) FR2603586B1 (de)
GB (1) GB2190676B (de)
GR (1) GR870803B (de)
HU (1) HU197570B (de)
IL (1) IL82612A0 (de)
IT (1) IT1205031B (de)
LU (1) LU86896A1 (de)
NL (1) NL8701226A (de)
NZ (1) NZ220345A (de)
PT (1) PT84938B (de)
SE (1) SE465163B (de)
ZA (1) ZA873583B (de)

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US5158958A (en) * 1992-04-03 1992-10-27 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
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TW593317B (en) 1993-06-21 2004-06-21 Janssen Pharmaceutica Nv Positive cardiac inotropic and lusitropic pyrroloquinolinone derivatives
US6756382B2 (en) 1999-06-10 2004-06-29 3M Innovative Properties Company Amide substituted imidazoquinolines
US6541485B1 (en) 1999-06-10 2003-04-01 3M Innovative Properties Company Urea substituted imidazoquinolines
US6331539B1 (en) * 1999-06-10 2001-12-18 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines
US6573273B1 (en) 1999-06-10 2003-06-03 3M Innovative Properties Company Urea substituted imidazoquinolines
JP4767429B2 (ja) * 2001-03-02 2011-09-07 株式会社クラレ 架橋剤および架橋性重合体
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CA2535117A1 (en) 2003-08-12 2005-03-03 3M Innovative Properties Company Oxime substituted imidazo-containing compounds
EP1658076B1 (de) 2003-08-27 2013-03-06 3M Innovative Properties Company Aryloxy- und arylalkylenoxy-substituierte imidazochinoline
CA2537763A1 (en) 2003-09-05 2005-03-17 3M Innovative Properties Company Treatment for cd5+ b cell lymphoma
EP1673087B1 (de) 2003-10-03 2015-05-13 3M Innovative Properties Company Alkoxy-substituierte imidazochinoline
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
US7897767B2 (en) 2003-11-14 2011-03-01 3M Innovative Properties Company Oxime substituted imidazoquinolines
US8598192B2 (en) 2003-11-14 2013-12-03 3M Innovative Properties Company Hydroxylamine substituted imidazoquinolines
RU2409576C2 (ru) 2003-11-25 2011-01-20 3М Инновейтив Пропертиз Компани Системы, содержащие имидазольное кольцо с заместителями, и способы их получения
EP1701955A1 (de) 2003-12-29 2006-09-20 3M Innovative Properties Company Arylalkenyl- und arylalkinylsubstituierte imidazochinoline
US8735421B2 (en) 2003-12-30 2014-05-27 3M Innovative Properties Company Imidazoquinolinyl sulfonamides
CA2559863A1 (en) 2004-03-24 2005-10-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
US8017779B2 (en) 2004-06-15 2011-09-13 3M Innovative Properties Company Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
US7897609B2 (en) 2004-06-18 2011-03-01 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
US8026366B2 (en) 2004-06-18 2011-09-27 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
WO2006065280A2 (en) 2004-06-18 2006-06-22 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
JP5313502B2 (ja) 2004-12-30 2013-10-09 スリーエム イノベイティブ プロパティズ カンパニー 置換キラル縮合［１，２］イミダゾ［４，５−ｃ］環状化合物
AU2005322898B2 (en) 2004-12-30 2011-11-24 3M Innovative Properties Company Chiral fused (1,2)imidazo(4,5-c) ring compounds
US9248127B2 (en) 2005-02-04 2016-02-02 3M Innovative Properties Company Aqueous gel formulations containing immune response modifiers
US7968563B2 (en) 2005-02-11 2011-06-28 3M Innovative Properties Company Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
US7943636B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company 1-substituted pyrazolo (3,4-C) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
AU2006232377A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. Pyrazolopyridine-1,4-diamines and analogs thereof
EP2258358A3 (de) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenese mit Acetylcholinesterasehemmer
CA2620333A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP1940389A2 (de) 2005-10-21 2008-07-09 Braincells, Inc. Modulation von neurogenese durch pde-hemmung
JP2009513672A (ja) 2005-10-31 2009-04-02 ブレインセルス，インコーポレイティド 神経発生のｇａｂａ受容体媒介調節
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
JP2009536669A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド アンジオテンシン調節による神経新生
CA2651862A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
US7906506B2 (en) 2006-07-12 2011-03-15 3M Innovative Properties Company Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
US8227603B2 (en) 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
US7598248B2 (en) 2006-08-02 2009-10-06 Cytokinetics, Inc. Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols, compositions thereof, and methods for their use
US8299248B2 (en) 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
WO2008030651A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008121333A1 (en) * 2007-03-30 2008-10-09 Cytokinetics, Incorporated Certain chemical entities, compositions and methods
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
KR101951220B1 (ko) 2011-07-13 2019-02-22 싸이토키네틱스, 인코포레이티드 조합 als 치료법
EP2804603A1 (de) 2012-01-10 2014-11-26 President and Fellows of Harvard College Betazellen-replikation für promoterverbindungen und verwendungsverfahren dafür

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US3932407A (en) * 1973-11-19 1976-01-13 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
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IL62402A0 (en) * 1980-03-24 1981-05-20 Sterling Drug Inc Imidazo(4,5-b)pyridines,their preparation and pharmaceutical compositions containing them
US4490371A (en) * 1983-02-16 1984-12-25 Syntex (U.S.A.) Inc. N,N-Disubstituted-(2-oxo-1,2,3,5-tetrahydroimidazo-[2,1-B]quinazolinyl)oxyalkylamides
JPS604186A (ja) * 1983-06-21 1985-01-10 Dai Ichi Seiyaku Co Ltd イミダゾキナゾリン化合物
JPS6028979A (ja) * 1983-07-14 1985-02-14 Dai Ichi Seiyaku Co Ltd イミダゾキナゾリン類化合物
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US4668686A (en) * 1985-04-25 1987-05-26 Bristol-Myers Company Imidazoquinoline antithrombrogenic cardiotonic agents

Also Published As

Publication number Publication date
DK166084B (da) 1993-03-08
IT8720650A0 (it) 1987-05-22
IL82612A0 (en) 1987-11-30
BE1002033A4 (fr) 1990-05-29
JPS62283972A (ja) 1987-12-09
GR870803B (en) 1987-09-24
ZA873583B (en) 1988-04-27
AU7299387A (en) 1987-11-26
US4775674A (en) 1988-10-04
PT84938A (en) 1987-06-01
FI86723C (fi) 1992-10-12
AU603577B2 (en) 1990-11-22
LU86896A1 (fr) 1988-01-20
KR870011137A (ko) 1987-12-21
SE8702158D0 (sv) 1987-05-22
ES2005588A6 (es) 1989-03-16
FR2603586A1 (fr) 1988-03-11
AT392790B (de) 1991-06-10
HUT43602A (en) 1987-11-30
CA1289137C (en) 1991-09-17
DK263587A (da) 1987-11-24
FI86723B (fi) 1992-06-30
IT1205031B (it) 1989-03-10
GB2190676A (en) 1987-11-25
SE465163B (sv) 1991-08-05
FR2603586B1 (fr) 1990-12-28
DE3717291A1 (de) 1987-11-26
GB2190676B (en) 1990-05-30
NL8701226A (nl) 1987-12-16
KR900008567B1 (ko) 1990-11-24
DK263587D0 (da) 1987-05-22
ATA132087A (de) 1990-11-15
PT84938B (pt) 1990-02-08
SE8702158L (sv) 1987-11-24
NZ220345A (en) 1990-10-26
CH675246A5 (de) 1990-09-14
GB8711839D0 (en) 1987-06-24
FI872220A (fi) 1987-11-24
HU197570B (en) 1989-04-28
FI872220A0 (fi) 1987-05-20

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