DK1654280T3 - Fremstilling af somatostatinpeptider - Google Patents

Fremstilling af somatostatinpeptider

Info

Publication number
DK1654280T3
DK1654280T3 DK04763881T DK04763881T DK1654280T3 DK 1654280 T3 DK1654280 T3 DK 1654280T3 DK 04763881 T DK04763881 T DK 04763881T DK 04763881 T DK04763881 T DK 04763881T DK 1654280 T3 DK1654280 T3 DK 1654280T3
Authority
DK
Denmark
Prior art keywords
preparation
somatostatin peptides
somatostatin
peptides
Prior art date
Application number
DK04763881T
Other languages
Danish (da)
English (en)
Inventor
Heribert Hellstern
Werner Pachinger
Walter Prikoszovich
Bernhard Wietfeld
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK1654280T3 publication Critical patent/DK1654280T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK04763881T 2003-08-08 2004-08-06 Fremstilling af somatostatinpeptider DK1654280T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0318682.2A GB0318682D0 (en) 2003-08-08 2003-08-08 Organic compounds
PCT/EP2004/008850 WO2005014624A2 (en) 2003-08-08 2004-08-06 Preparation of somatostatin peptides

Publications (1)

Publication Number Publication Date
DK1654280T3 true DK1654280T3 (da) 2008-09-29

Family

ID=27839906

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04763881T DK1654280T3 (da) 2003-08-08 2004-08-06 Fremstilling af somatostatinpeptider

Country Status (35)

Country Link
US (1) US7615609B2 (pt)
EP (1) EP1654280B8 (pt)
JP (1) JP4580928B2 (pt)
KR (1) KR101136633B1 (pt)
CN (2) CN1832962A (pt)
AR (1) AR045327A1 (pt)
AT (1) ATE394424T1 (pt)
AU (1) AU2004262570B2 (pt)
BR (1) BRPI0413437B1 (pt)
CA (1) CA2534224C (pt)
CO (1) CO5660271A2 (pt)
CY (1) CY1108775T1 (pt)
DE (1) DE602004013599D1 (pt)
DK (1) DK1654280T3 (pt)
EC (1) ECSP066352A (pt)
ES (1) ES2307039T3 (pt)
GB (1) GB0318682D0 (pt)
HK (1) HK1090065A1 (pt)
HR (1) HRP20080350T3 (pt)
IL (1) IL173272A (pt)
IS (1) IS2894B (pt)
MA (1) MA27982A1 (pt)
MX (1) MXPA06001525A (pt)
MY (1) MY141731A (pt)
NO (1) NO338367B1 (pt)
NZ (1) NZ544961A (pt)
PE (2) PE20050356A1 (pt)
PL (1) PL1654280T3 (pt)
PT (1) PT1654280E (pt)
RU (1) RU2360921C2 (pt)
SI (1) SI1654280T1 (pt)
TN (1) TNSN06045A1 (pt)
TW (1) TWI345570B (pt)
WO (1) WO2005014624A2 (pt)
ZA (1) ZA200600584B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5331817B2 (ja) * 2007-12-03 2013-10-30 イタルファルマコ ソシエタ ペル アチオニ 新規な非選択的ソマトスタチン類似体
EP2067786A1 (en) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Novel non selective analogs of somatostatin
ES2522167T3 (es) 2010-01-05 2014-11-13 National Dong Hwa University Formulación anticancerosa
CN103467575B (zh) * 2013-08-22 2016-03-02 深圳翰宇药业股份有限公司 一种帕西瑞肽的制备方法
CN103641894B (zh) * 2013-12-06 2015-10-28 深圳翰宇药业股份有限公司 一种治疗库欣病的多肽药物的制备方法
EP3233899B1 (en) * 2014-12-19 2020-06-24 Auro Peptides LTD A process for the preparation of pasireotide
CN106188231B (zh) * 2015-05-25 2021-10-22 中国医学科学院药物研究所 帕西瑞肽五肽中间体的合成与应用
CN114621326B (zh) * 2020-12-10 2023-12-26 武汉武药科技有限公司 门冬氨酸帕瑞肽及其中间体和其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3303345A1 (de) * 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Cyclische peptide mit somatostatin-wirkung
EP0255224A3 (en) 1986-06-30 1990-04-18 Merck & Co. Inc. Cyclic and bridged cyclic somatostatin analogs useful as analgesic agents
US5811512A (en) 1991-08-22 1998-09-22 The Trustees Of The University Of Pennsylvania Non-peptide peptidomimetics and related cyclic hexapeptides
SG48977A1 (en) * 1993-06-23 1998-05-18 Diatide Inc Radiolabeled peptides
US5770687A (en) 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
US6355613B1 (en) 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
GB0018891D0 (en) * 2000-08-01 2000-09-20 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
CN1832962A (zh) 2006-09-13
CA2534224A1 (en) 2005-02-17
TNSN06045A1 (en) 2007-10-03
HK1090065A1 (en) 2006-12-15
CN102127155B (zh) 2013-11-27
BRPI0413437A (pt) 2006-10-10
NZ544961A (en) 2008-08-29
PT1654280E (pt) 2008-08-18
RU2360921C2 (ru) 2009-07-10
KR20060070541A (ko) 2006-06-23
EP1654280A2 (en) 2006-05-10
MY141731A (en) 2010-06-15
CY1108775T1 (el) 2014-04-09
MXPA06001525A (es) 2006-05-15
US7615609B2 (en) 2009-11-10
AR045327A1 (es) 2005-10-26
PL1654280T3 (pl) 2008-10-31
PE20050356A1 (es) 2005-06-17
KR101136633B1 (ko) 2012-04-18
MA27982A1 (fr) 2006-07-03
WO2005014624A3 (en) 2005-09-22
IS2894B (is) 2014-09-15
TW200524955A (en) 2005-08-01
ATE394424T1 (de) 2008-05-15
SI1654280T1 (sl) 2008-10-31
NO20061125L (no) 2006-05-08
CO5660271A2 (es) 2006-07-31
AU2004262570A1 (en) 2005-02-17
IL173272A (en) 2012-03-29
IL173272A0 (en) 2006-06-11
ZA200600584B (en) 2006-12-27
ES2307039T3 (es) 2008-11-16
CN102127155A (zh) 2011-07-20
BRPI0413437B1 (pt) 2017-12-12
AU2004262570B2 (en) 2008-06-19
JP2007526899A (ja) 2007-09-20
HRP20080350T3 (en) 2008-08-31
WO2005014624A2 (en) 2005-02-17
EP1654280B8 (en) 2008-08-13
EP1654280B1 (en) 2008-05-07
GB0318682D0 (en) 2003-09-10
RU2006106721A (ru) 2007-09-20
DE602004013599D1 (de) 2008-06-19
JP4580928B2 (ja) 2010-11-17
IS8338A (is) 2006-03-02
US20060258838A1 (en) 2006-11-16
TWI345570B (en) 2011-07-21
NO338367B1 (no) 2016-08-15
ECSP066352A (es) 2006-08-30
CA2534224C (en) 2012-03-27
PE20091210A1 (es) 2009-09-07

Similar Documents

Publication Publication Date Title
DK2206517T3 (da) Immunpotentierende sammensætninger omfattende af anti-PD-L1-antistoffer
DK3395339T3 (da) Hurtigt opløsende formulering af cinacalcet-hcl
DK1737971T3 (da) Blandinger af bindingsproteiner
DK2172205T3 (da) Farmaceutisk formulering bestående af lanthan-forbindelser
DK1587542T3 (da) Anvendelse af anti-CD100-antistoffer
DK1687066T3 (da) Fremgangsmåder til immunmodulering
DK1517915T3 (da) Promedikamenter af excitatoriske aminosyrer
DK1840125T3 (da) Mellemprodukter til fremstilling af dioxan-2-alkylcarbamater
IS8338A (is) Framleiðsla sómatóstatínpeptíða
DE112004001799D2 (de) Tensidhaltiger Knochenzement
DK1575941T3 (da) Fremgangsmåde til fremstilling af (S)-pantoprazol
DK1625148T3 (da) Peptidkompleks
DE602004012512D1 (de) Komparator
NO20053512D0 (no) IL-8-liknende proteiner
NO20050436D0 (no) Beta-lagnedbrytende peptider
DE602004008992D1 (de) Herstellung von verzweigten Tetrasiloxanen
DE60308139D1 (de) Wasserdichter Drücker
ITMI20031514A1 (it) Ombrello
DE502004012380D1 (de) Bekleidungsstück
ITBR20030001A1 (it) Giunto h (acca)
NO20032626D0 (no) Teknisk ganghjelpemiddel
NO20031324D0 (no) Parex
UA7236S (uk) Паличка вафельна
SE0302982D0 (sv) Motvikts-lastbrygga
ITPN20030037A1 (it) Cocktail kiwino