DK165171C - Mikropartikel- og gasbobleholdigt ultralydskontrastmiddel samt udstyr og fremgangsmaade til dets fremstilling - Google Patents

Mikropartikel- og gasbobleholdigt ultralydskontrastmiddel samt udstyr og fremgangsmaade til dets fremstilling

Info

Publication number
DK165171C
DK165171C DK078984A DK78984A DK165171C DK 165171 C DK165171 C DK 165171C DK 078984 A DK078984 A DK 078984A DK 78984 A DK78984 A DK 78984A DK 165171 C DK165171 C DK 165171C
Authority
DK
Denmark
Prior art keywords
microparticle
procedure
manufacturing
equipment
controlling agent
Prior art date
Application number
DK078984A
Other languages
Danish (da)
English (en)
Other versions
DK165171B (da
DK78984A (da
DK78984D0 (da
Inventor
Juergen Hilmann
Lothar Lange
Ingfried Zimmermann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK78984D0 publication Critical patent/DK78984D0/da
Publication of DK78984A publication Critical patent/DK78984A/da
Publication of DK165171B publication Critical patent/DK165171B/da
Application granted granted Critical
Publication of DK165171C publication Critical patent/DK165171C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3925Markers, e.g. radio-opaque or breast lesions markers ultrasonic

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Public Health (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
  • Fire-Detection Mechanisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DK078984A 1983-04-15 1984-02-20 Mikropartikel- og gasbobleholdigt ultralydskontrastmiddel samt udstyr og fremgangsmaade til dets fremstilling DK165171C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3313946A DE3313946A1 (de) 1983-04-15 1983-04-15 Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel
DE3313946 1983-04-15

Publications (4)

Publication Number Publication Date
DK78984D0 DK78984D0 (da) 1984-02-20
DK78984A DK78984A (da) 1984-10-16
DK165171B DK165171B (da) 1992-10-19
DK165171C true DK165171C (da) 1993-03-01

Family

ID=6196665

Family Applications (1)

Application Number Title Priority Date Filing Date
DK078984A DK165171C (da) 1983-04-15 1984-02-20 Mikropartikel- og gasbobleholdigt ultralydskontrastmiddel samt udstyr og fremgangsmaade til dets fremstilling

Country Status (12)

Country Link
EP (1) EP0122624B1 (enExample)
JP (1) JPS59205328A (enExample)
AT (1) ATE36958T1 (enExample)
AU (1) AU566928B2 (enExample)
CA (1) CA1239092A (enExample)
DE (2) DE3313946A1 (enExample)
DK (1) DK165171C (enExample)
FI (1) FI81264C (enExample)
IE (1) IE57272B1 (enExample)
NO (1) NO161356C (enExample)
NZ (1) NZ207853A (enExample)
ZA (1) ZA842801B (enExample)

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US5141738A (en) * 1983-04-15 1992-08-25 Schering Aktiengesellschaft Ultrasonic contrast medium comprising gas bubbles and solid lipophilic surfactant-containing microparticles and use thereof
DE3313947A1 (de) * 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel
DK151366C (da) * 1984-12-05 1988-05-16 Tytex As Trusse samt fremgangsmaade til fremstilling heraf
DE3637926C1 (de) * 1986-11-05 1987-11-26 Schering Ag Ultraschall-Manometrieverfahren in einer Fluessigkeit mittels Mikroblaeschen
DE3741199A1 (de) * 1987-12-02 1989-08-17 Schering Ag Verwendung von ultraschallkontrastmitteln fuer die ultraschall-lithotripsie
DE3741201A1 (de) * 1987-12-02 1989-06-15 Schering Ag Ultraschallarbeitsverfahren und mittel zu dessen durchfuehrung
DE3803972A1 (de) * 1988-02-05 1989-08-10 Schering Ag Ultraschallkontrastmittel
DE3803971C2 (de) * 1988-02-05 1997-09-18 Schering Ag Ultraschallkontrastmittel
DE58908194D1 (de) 1988-02-05 1994-09-22 Schering Ag Ultraschallkontrastmittel, verfahren zu deren herstellung und deren verwendung als diagnostika und therapeutika.
US5425366A (en) * 1988-02-05 1995-06-20 Schering Aktiengesellschaft Ultrasonic contrast agents for color Doppler imaging
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US5445813A (en) 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
US5578292A (en) 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US6989141B2 (en) 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6613306B1 (en) 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
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US7083778B2 (en) 1991-05-03 2006-08-01 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
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US5205287A (en) * 1990-04-26 1993-04-27 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
US5190982A (en) * 1990-04-26 1993-03-02 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
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ATE151993T1 (de) * 1991-07-05 1997-05-15 Nycomed Imaging As Verbesserungen an kontrastmitteln
AU2317592A (en) * 1991-07-05 1993-02-11 University Of Rochester Ultrasmall non-aggregated porous particles entrapping gas-bubbles
JPH0521183U (ja) * 1991-09-02 1993-03-19 サンデン株式会社 回転斜板式圧縮機
GB9200391D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
GB9200387D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
DE69432295T2 (de) * 1993-12-15 2003-08-14 Bracco Research Sa Gas-mischungen verwendbar als ultraschallkontrastmittel
DE4406474A1 (de) * 1994-02-23 1995-08-24 Schering Ag Gas enthaltende Mikropartikel, diese enthaltende Mittel, deren Verwendung in der Ultraschalldiagnostik, sowie Verfahren zur Herstellung der Partikel und Mittel
DE19510690A1 (de) * 1995-03-14 1996-09-19 Schering Ag Polymere Nano- und/oder Mikropartikel, Verfahren zu deren Herstellung, sowie Verwendung in medizinischen Diagnostik und Therapie
DE19543077C2 (de) * 1995-11-13 1997-10-16 Schering Ag Verwendung von gashaltigen Metallkomplexen als Ultraschallkontrastmittel
DE19602930A1 (de) * 1996-01-18 1997-07-24 Schering Ag Poröse Matrices aus niedermolekularen Substanzen zur Genierung stabiler Gasblasensuspensionen, deren Verwendung als Ultraschallkontrastmittel sowie Verfahren zu deren Herstellung
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JP3819845B2 (ja) 2001-04-06 2006-09-13 ブラッコ・リサーチ・ソシエテ・アノニム 流体で充填された空洞内の局所物理パラメータの改善された測定方法
EP1647232B1 (en) 2001-12-03 2011-08-17 Ekos Corporation Catheter with multiple ultrasound radiating members
US7211240B2 (en) 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
AU2003278807A1 (en) 2002-03-01 2004-08-13 Bracco International B.V. Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy
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US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
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Also Published As

Publication number Publication date
ZA842801B (en) 1984-11-28
IE840835L (en) 1984-10-15
DK165171B (da) 1992-10-19
AU566928B2 (en) 1987-11-05
NZ207853A (en) 1988-01-08
AU2680584A (en) 1984-10-18
NO161356B (no) 1989-05-02
JPH0425934B2 (enExample) 1992-05-06
FI81264C (fi) 1990-10-10
EP0122624A2 (de) 1984-10-24
DE3473828D1 (en) 1988-10-13
DK78984A (da) 1984-10-16
FI841462L (fi) 1984-10-16
NO161356C (no) 1989-08-09
FI841462A0 (fi) 1984-04-12
FI81264B (fi) 1990-06-29
ATE36958T1 (de) 1988-09-15
DK78984D0 (da) 1984-02-20
JPS59205328A (ja) 1984-11-20
IE57272B1 (en) 1992-07-01
CA1239092A (en) 1988-07-12
EP0122624A3 (en) 1986-11-20
NO841489L (no) 1984-10-16
EP0122624B1 (de) 1988-09-07
DE3313946A1 (de) 1984-10-18

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