DK165171C - Mikropartikel- og gasbobleholdigt ultralydskontrastmiddel samt udstyr og fremgangsmaade til dets fremstilling - Google Patents

Mikropartikel- og gasbobleholdigt ultralydskontrastmiddel samt udstyr og fremgangsmaade til dets fremstilling

Info

Publication number
DK165171C
DK165171C DK078984A DK78984A DK165171C DK 165171 C DK165171 C DK 165171C DK 078984 A DK078984 A DK 078984A DK 78984 A DK78984 A DK 78984A DK 165171 C DK165171 C DK 165171C
Authority
DK
Denmark
Prior art keywords
microparticle
procedure
manufacturing
equipment
controlling agent
Prior art date
Application number
DK078984A
Other languages
English (en)
Other versions
DK78984D0 (da
DK78984A (da
DK165171B (da
Inventor
Juergen Hilmann
Lothar Lange
Ingfried Zimmermann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK78984D0 publication Critical patent/DK78984D0/da
Publication of DK78984A publication Critical patent/DK78984A/da
Publication of DK165171B publication Critical patent/DK165171B/da
Application granted granted Critical
Publication of DK165171C publication Critical patent/DK165171C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3925—Markers, e.g. radio-opaque or breast lesions markers ultrasonic

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fire-Detection Mechanisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DK078984A 1983-04-15 1984-02-20 Mikropartikel- og gasbobleholdigt ultralydskontrastmiddel samt udstyr og fremgangsmaade til dets fremstilling DK165171C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3313946A DE3313946A1 (de) 1983-04-15 1983-04-15 Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel
DE3313946 1983-04-15

Publications (4)

Publication Number Publication Date
DK78984D0 DK78984D0 (da) 1984-02-20
DK78984A DK78984A (da) 1984-10-16
DK165171B DK165171B (da) 1992-10-19
DK165171C true DK165171C (da) 1993-03-01

Family

ID=6196665

Family Applications (1)

Application Number Title Priority Date Filing Date
DK078984A DK165171C (da) 1983-04-15 1984-02-20 Mikropartikel- og gasbobleholdigt ultralydskontrastmiddel samt udstyr og fremgangsmaade til dets fremstilling

Country Status (12)

Country Link
EP (1) EP0122624B1 (da)
JP (1) JPS59205328A (da)
AT (1) ATE36958T1 (da)
AU (1) AU566928B2 (da)
CA (1) CA1239092A (da)
DE (2) DE3313946A1 (da)
DK (1) DK165171C (da)
FI (1) FI81264C (da)
IE (1) IE57272B1 (da)
NO (1) NO161356C (da)
NZ (1) NZ207853A (da)
ZA (1) ZA842801B (da)

Families Citing this family (84)

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DE3834705A1 (de) * 1988-10-07 1990-04-12 Schering Ag Ultraschallkontrastmittel aus gasblaeschen und fettsaeure enthaltenden mikropartikeln
DE3313947A1 (de) * 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel
DK151366C (da) * 1984-12-05 1988-05-16 Tytex As Trusse samt fremgangsmaade til fremstilling heraf
DE3637926C1 (de) * 1986-11-05 1987-11-26 Schering Ag Ultraschall-Manometrieverfahren in einer Fluessigkeit mittels Mikroblaeschen
DE3741201A1 (de) * 1987-12-02 1989-06-15 Schering Ag Ultraschallarbeitsverfahren und mittel zu dessen durchfuehrung
DE3741199A1 (de) * 1987-12-02 1989-08-17 Schering Ag Verwendung von ultraschallkontrastmitteln fuer die ultraschall-lithotripsie
US5425366A (en) * 1988-02-05 1995-06-20 Schering Aktiengesellschaft Ultrasonic contrast agents for color Doppler imaging
DE3803971C2 (de) * 1988-02-05 1997-09-18 Schering Ag Ultraschallkontrastmittel
DE3803972A1 (de) * 1988-02-05 1989-08-10 Schering Ag Ultraschallkontrastmittel
DE58908194D1 (de) 1988-02-05 1994-09-22 Schering Ag Ultraschallkontrastmittel, verfahren zu deren herstellung und deren verwendung als diagnostika und therapeutika.
US5922304A (en) * 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
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US6613306B1 (en) 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5578292A (en) 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US6989141B2 (en) 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
USRE39146E1 (en) 1990-04-02 2006-06-27 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US5445813A (en) 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
US7083778B2 (en) 1991-05-03 2006-08-01 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5190982A (en) * 1990-04-26 1993-03-02 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
US5205287A (en) * 1990-04-26 1993-04-27 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
US5137928A (en) * 1990-04-26 1992-08-11 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
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US5147631A (en) * 1991-04-30 1992-09-15 Du Pont Merck Pharmaceutical Company Porous inorganic ultrasound contrast agents
ES2103947T5 (es) † 1991-06-03 2001-05-16 Nycomed Imaging As Mejoras introducidas en o relacionadas con agentes de contraste.
IE80926B1 (en) * 1991-07-05 1999-06-30 Nycomed Imaging As Improvements in or relating to contrast agents
JPH06511481A (ja) * 1991-07-05 1994-12-22 ユニバーシティ オブ ロチェスター 気泡を取り込む超微小非凝集多孔質粒子
JPH0521183U (ja) * 1991-09-02 1993-03-19 サンデン株式会社 回転斜板式圧縮機
GB9200387D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
GB9200391D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them
RU2138293C1 (ru) 1993-12-15 1999-09-27 Бракко Рисерч С.А. Контрастные вещества для ультразвуковой эхографии, контрастные средства, содержащие эти вещества, и способы их приготовления
DE4406474A1 (de) * 1994-02-23 1995-08-24 Schering Ag Gas enthaltende Mikropartikel, diese enthaltende Mittel, deren Verwendung in der Ultraschalldiagnostik, sowie Verfahren zur Herstellung der Partikel und Mittel
DE19510690A1 (de) 1995-03-14 1996-09-19 Schering Ag Polymere Nano- und/oder Mikropartikel, Verfahren zu deren Herstellung, sowie Verwendung in medizinischen Diagnostik und Therapie
DE19543077C2 (de) * 1995-11-13 1997-10-16 Schering Ag Verwendung von gashaltigen Metallkomplexen als Ultraschallkontrastmittel
DE19602930A1 (de) * 1996-01-18 1997-07-24 Schering Ag Poröse Matrices aus niedermolekularen Substanzen zur Genierung stabiler Gasblasensuspensionen, deren Verwendung als Ultraschallkontrastmittel sowie Verfahren zu deren Herstellung
DE19813174A1 (de) * 1998-03-25 1999-05-27 Schering Ag Mikropartikel aus Polymeren und mindestens einer gerüstbildenden Komponente und ihre Herstellung und Verwendung in der Ultraschalldiagnostik und zur ultraschallinduzierten Wirkstofffreisetzung
WO2000021578A1 (en) 1998-10-12 2000-04-20 Mallinckrodt Inc. Novel ultrasound contrast agents
US6254852B1 (en) 1999-07-16 2001-07-03 Dupont Pharmaceuticals Company Porous inorganic targeted ultrasound contrast agents
EP2279757A3 (en) 2000-06-02 2011-08-03 Bracco Suisse SA Compounds for targeting endothelial cells
ATE376803T1 (de) 2001-04-06 2007-11-15 Bracco Research Sa Vorrichtung zur messung lokaler physikalischer parameter in einem flüssigkeitsgefüllten hohlraum
ATE319378T1 (de) 2001-12-03 2006-03-15 Ekos Corp Katheter mit mehreren ultraschall-abstrahlenden teilen
US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US7211240B2 (en) 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
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US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
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US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
ES2557286T3 (es) 2003-03-03 2016-01-25 Dyax Corp. Usos de péptidos que se unen específicamente al receptor del HGF (cMet)
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
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US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
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US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US7967763B2 (en) 2005-09-07 2011-06-28 Cabochon Aesthetics, Inc. Method for treating subcutaneous tissues
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9358033B2 (en) 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
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US4277367A (en) * 1978-10-23 1981-07-07 Wisconsin Alumni Research Foundation Phantom material and method
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Also Published As

Publication number Publication date
EP0122624A3 (en) 1986-11-20
DE3473828D1 (en) 1988-10-13
CA1239092A (en) 1988-07-12
FI841462A (fi) 1984-10-16
DK78984D0 (da) 1984-02-20
JPH0425934B2 (da) 1992-05-06
NO841489L (no) 1984-10-16
JPS59205328A (ja) 1984-11-20
EP0122624A2 (de) 1984-10-24
IE57272B1 (en) 1992-07-01
DK78984A (da) 1984-10-16
AU2680584A (en) 1984-10-18
FI81264C (fi) 1990-10-10
EP0122624B1 (de) 1988-09-07
DE3313946A1 (de) 1984-10-18
NZ207853A (en) 1988-01-08
ATE36958T1 (de) 1988-09-15
DK165171B (da) 1992-10-19
AU566928B2 (en) 1987-11-05
FI841462A0 (fi) 1984-04-12
ZA842801B (en) 1984-11-28
NO161356B (no) 1989-05-02
FI81264B (fi) 1990-06-29
NO161356C (no) 1989-08-09
IE840835L (en) 1984-10-15

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