DK163107B - Fremgangsmaade til fremstilling af et koncentrat af antihaemofilisk faktor med hoej renhed - Google Patents
Fremgangsmaade til fremstilling af et koncentrat af antihaemofilisk faktor med hoej renhed Download PDFInfo
- Publication number
- DK163107B DK163107B DK450785A DK450785A DK163107B DK 163107 B DK163107 B DK 163107B DK 450785 A DK450785 A DK 450785A DK 450785 A DK450785 A DK 450785A DK 163107 B DK163107 B DK 163107B
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- DK
- Denmark
- Prior art keywords
- approx
- weight
- precipitate
- solution
- polyethylene glycol
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
- Y10S530/83—Plasma; serum
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/658,081 US4543210A (en) | 1984-10-04 | 1984-10-04 | Process for producing a high purity antihemophilic factor concentrate |
| US65808184 | 1984-10-04 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK450785D0 DK450785D0 (da) | 1985-10-03 |
| DK450785A DK450785A (da) | 1986-04-05 |
| DK163107B true DK163107B (da) | 1992-01-20 |
Family
ID=24639818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK450785A DK163107B (da) | 1984-10-04 | 1985-10-03 | Fremgangsmaade til fremstilling af et koncentrat af antihaemofilisk faktor med hoej renhed |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4543210A (de) |
| EP (1) | EP0176926B1 (de) |
| JP (1) | JPH0676337B2 (de) |
| AT (1) | ATE44236T1 (de) |
| CA (1) | CA1243950A (de) |
| DE (1) | DE3571201D1 (de) |
| DK (1) | DK163107B (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1984003628A1 (en) * | 1983-05-09 | 1984-09-27 | Nordisk Insulinlab | A concentrate of the antihemophilic factor viii and a process for producing it |
| SE8501050D0 (sv) * | 1985-03-05 | 1985-03-05 | Kabivitrum Ab | Biologically active fragments of human antihemophilic factor and method for preparation thereof |
| AU6487286A (en) * | 1985-11-08 | 1987-05-14 | Baxter Travenol Laboratories Inc. | Antihemophilic factor by cold precipitation |
| EP0238701B1 (de) * | 1986-03-27 | 1992-03-18 | Octapharma AG | Verfahren zur Herstellung eines hochgereinigten Antihämophilie-Faktors |
| AT391808B (de) * | 1986-11-03 | 1990-12-10 | Immuno Ag | Verfahren zur herstellung einer faktor viii (ahf)-haeltigen fraktion |
| EP0321835B1 (de) * | 1987-12-21 | 1994-09-28 | Miles Inc. | Faktor VIII- Gelfiltration |
| US5177191A (en) * | 1987-12-21 | 1993-01-05 | Miles, Inc. | Gel filtration of factor VIII |
| FR2632309B1 (fr) * | 1988-06-07 | 1990-08-24 | Lille Transfusion Sanguine | Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus |
| DE3904354A1 (de) * | 1989-02-14 | 1990-08-16 | Behringwerke Ag | Pasteurisiertes, gereinigtes von willebrand-faktor-konzentrat und verfahren zu seiner herstellung |
| ES2042138T3 (es) * | 1989-05-24 | 1993-12-01 | Miles Inc. | Filtracion en gel del factor viii tratado termicamente. |
| USH1509H (en) * | 1989-06-09 | 1995-12-05 | Eran; Harutyun | Heparin enhanced process for separating antihemophilic factor (Factor VIII) and fibronectin from cryoprecipitate |
| FR2651437A1 (fr) * | 1989-09-05 | 1991-03-08 | Lille Transfusion Sanguine | Procede de preparation de concentre du complexe facteur viii-facteur von willebrand de la coagulation sanguine a partir de plasma total. |
| DK162233C (da) * | 1989-11-09 | 1992-03-16 | Novo Nordisk As | Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii |
| IT1248723B (it) * | 1990-06-12 | 1995-01-26 | Scalvo S P A | Processo per la purificazione del fattore viii e fattore viii ottenuto con tale processo |
| FR2664165B1 (fr) * | 1990-07-03 | 1992-10-16 | Lille Transfusion Sanguine | Composition pour stabiliser le plasma sanguin en cours de pasteurisation. |
| US5525519A (en) * | 1992-01-07 | 1996-06-11 | Middlesex Sciences, Inc. | Method for isolating biomolecules from a biological sample with linear polymers |
| DE4202667C1 (de) * | 1992-01-29 | 1993-05-13 | Behringwerke Ag, 3550 Marburg, De | |
| US5288853A (en) * | 1992-04-30 | 1994-02-22 | Alpha Therapeutic Corporation | Factor viii purification process |
| US5659017A (en) * | 1995-11-07 | 1997-08-19 | Alpha Therapeutic Corporation | Anion exchange process for the purification of Factor VIII |
| JP5149470B2 (ja) | 1999-02-22 | 2013-02-20 | バクスター・インターナショナル・インコーポレイテッド | 新規のアルブミンを含有していない第ｖｉｉｉ因子処方物 |
| JP5080713B2 (ja) * | 1999-12-20 | 2012-11-21 | 田辺三菱製薬株式会社 | 多孔性膜処理によるウイルスの除去された血漿蛋白組成物の製造方法、ウイルスの除去された血漿蛋白組成物およびウイルス除去方法 |
| CA2742328C (en) | 2008-11-07 | 2019-02-26 | Baxter International Inc. | Factor viii formulations |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US29698A (en) * | 1860-08-21 | Improvement in harvesters | ||
| NL286954A (de) * | 1962-01-03 | |||
| US3652530A (en) * | 1967-08-28 | 1972-03-28 | American Nat Red Cross | Antihemophilic factor prepared from blood plasma using polyethylene glycol |
| US3631018A (en) * | 1970-05-01 | 1971-12-28 | Baxter Laboratories Inc | Production of stable high-potency human ahf using polyethylene glycol and glycine to fractionate a cryoprecipitate of ahf concentrate |
| US3682881A (en) * | 1970-10-02 | 1972-08-08 | Baxter Laboratories Inc | Fractionation of plasma using glycine and polyethylene glycol |
| US3803115A (en) * | 1972-05-17 | 1974-04-09 | Baxter Laboratories Inc | Stabilization of ahf using heparin |
| US4188318A (en) * | 1975-06-16 | 1980-02-12 | Edward Shanbrom | Simplified method for preparation of high yield, high purity Factor VIII concentrate |
| US4069216A (en) * | 1975-06-16 | 1978-01-17 | Edward Shanbrom, Inc. | Simplified methods for preparation of very high purity Factor VIII concentrate |
| US4104266A (en) * | 1977-04-14 | 1978-08-01 | American National Red Cross | Method for preparation of antihemophilic factor |
| CA1074698A (en) * | 1977-12-19 | 1980-04-01 | Gail A. Rock | Method of collecting anti-hemophilic factor viii from blood and blood plasma |
| US4170639A (en) * | 1978-07-10 | 1979-10-09 | Warner-Lambert Company | Antihemophilic factor concentrate and its production |
| US4210580A (en) * | 1979-06-19 | 1980-07-01 | David Amrani | Process for separation and isolation of AHF and fibronectin from blood plasma |
| FR2460305A2 (fr) * | 1979-06-29 | 1981-01-23 | Merieux Inst | Procede de preparation d'un concentre de facteur viii |
| SE448945B (sv) * | 1979-12-20 | 1987-03-30 | Blombaeck E G B | Forfarande for rening och /eller koncentrering av faktor viii-komplexet |
| US4289691A (en) * | 1980-01-18 | 1981-09-15 | The Canadian Red Cross Society | Method of obtaining intermediate purity factor VIII |
| US4386068A (en) * | 1980-02-26 | 1983-05-31 | Cutter Laboratories, Inc. | Antihemophilic factor concentrate and method for preparation |
| US4294826A (en) * | 1980-05-07 | 1981-10-13 | Armour Pharmaceutical Company | Process for the preparation of highly purified antihemophilic factor |
| AT369263B (de) * | 1980-08-27 | 1982-12-27 | Immuno Ag | Verfahren zur herstellung eines faktor viii(ahf) -hochkonzentrates |
| US4359463A (en) * | 1980-11-26 | 1982-11-16 | Rock Gail A | Stabilization of Factor VIII activity in whole blood or blood plasma |
| US4435318A (en) * | 1981-05-22 | 1984-03-06 | Ionics, Incorporated | Electrodialysis preparation of purified AHF concentrate |
| CA1178887A (en) * | 1981-10-01 | 1984-12-04 | Gail A. Rock | Factor viii concentrates prepared from heparinized plasma by the application of a cold precipitation technique |
| US4495175A (en) * | 1982-08-05 | 1985-01-22 | University Of Rochester | Preparation of highly purified human antihemophilic factor |
| US4486410A (en) * | 1984-02-09 | 1984-12-04 | Armour Pharmaceutical Company | Heat defibrinogenation of AHF preparation |
-
1984
- 1984-10-04 US US06/658,081 patent/US4543210A/en not_active Expired - Lifetime
-
1985
- 1985-06-28 CA CA000486007A patent/CA1243950A/en not_active Expired
- 1985-07-31 JP JP60167835A patent/JPH0676337B2/ja not_active Expired - Lifetime
- 1985-09-24 AT AT85112070T patent/ATE44236T1/de not_active IP Right Cessation
- 1985-09-24 EP EP85112070A patent/EP0176926B1/de not_active Expired
- 1985-09-24 DE DE8585112070T patent/DE3571201D1/de not_active Expired
- 1985-10-03 DK DK450785A patent/DK163107B/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0176926B1 (de) | 1989-06-28 |
| EP0176926A3 (en) | 1987-10-28 |
| DE3571201D1 (en) | 1989-08-03 |
| ATE44236T1 (de) | 1989-07-15 |
| CA1243950A (en) | 1988-11-01 |
| JPS6187626A (ja) | 1986-05-06 |
| US4543210A (en) | 1985-09-24 |
| EP0176926A2 (de) | 1986-04-09 |
| JPH0676337B2 (ja) | 1994-09-28 |
| DK450785D0 (da) | 1985-10-03 |
| DK450785A (da) | 1986-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PRF | Application refused |