DK1593682T3 - 4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrazin-6-carboxarnid-forbindelser, fremgangsmåde til fremstilling heraf samt farmaceutiske sammensætninger indeholdende disse. - Google Patents

4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrazin-6-carboxarnid-forbindelser, fremgangsmåde til fremstilling heraf samt farmaceutiske sammensætninger indeholdende disse.

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Publication number
DK1593682T3
DK1593682T3 DK05290599T DK05290599T DK1593682T3 DK 1593682 T3 DK1593682 T3 DK 1593682T3 DK 05290599 T DK05290599 T DK 05290599T DK 05290599 T DK05290599 T DK 05290599T DK 1593682 T3 DK1593682 T3 DK 1593682T3
Authority
DK
Denmark
Prior art keywords
tetrahydropyrrolo
pyrazine
oxo
preparation
pharmaceutical compositions
Prior art date
Application number
DK05290599T
Other languages
English (en)
Inventor
Nanteuil Guillaume De
Philippe Gloanec
Jean-Gilles Parmentier
Alain Benoist
Alain Rupin
Marie-Odile Vallez
Tony Verbeuren
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of DK1593682T3 publication Critical patent/DK1593682T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A47FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47JKITCHEN EQUIPMENT; COFFEE MILLS; SPICE MILLS; APPARATUS FOR MAKING BEVERAGES
    • A47J27/00Cooking-vessels
    • A47J27/14Cooking-vessels for use in hotels, restaurants, or canteens
    • A47J27/16Cooking-vessels for use in hotels, restaurants, or canteens heated by steam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • AHUMAN NECESSITIES
    • A47FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47JKITCHEN EQUIPMENT; COFFEE MILLS; SPICE MILLS; APPARATUS FOR MAKING BEVERAGES
    • A47J27/00Cooking-vessels
    • A47J27/12Multiple-unit cooking vessels
    • A47J27/13Tier cooking-vessels
    • AHUMAN NECESSITIES
    • A47FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47JKITCHEN EQUIPMENT; COFFEE MILLS; SPICE MILLS; APPARATUS FOR MAKING BEVERAGES
    • A47J36/00Parts, details or accessories of cooking-vessels
    • A47J36/24Warming devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK05290599T 2004-03-19 2005-03-18 4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrazin-6-carboxarnid-forbindelser, fremgangsmåde til fremstilling heraf samt farmaceutiske sammensætninger indeholdende disse. DK1593682T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0402841A FR2867780B1 (fr) 2004-03-19 2004-03-19 Nouveaux derives de 4-oxo-4,6,7,8-tetrahydropyrrolo (1,2-a) pyrazine-6-carboxamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
DK1593682T3 true DK1593682T3 (da) 2008-03-03

Family

ID=34896643

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05290599T DK1593682T3 (da) 2004-03-19 2005-03-18 4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrazin-6-carboxarnid-forbindelser, fremgangsmåde til fremstilling heraf samt farmaceutiske sammensætninger indeholdende disse.

Country Status (31)

Country Link
US (2) US7498330B2 (da)
EP (1) EP1593682B1 (da)
JP (1) JP2005272467A (da)
KR (1) KR100741236B1 (da)
CN (1) CN1297558C (da)
AR (1) AR048277A1 (da)
AT (1) ATE377601T1 (da)
AU (1) AU2005201198B8 (da)
BR (1) BRPI0500889A (da)
CA (1) CA2500575C (da)
CY (1) CY1107157T1 (da)
DE (1) DE602005003161T2 (da)
DK (1) DK1593682T3 (da)
EA (1) EA008688B1 (da)
ES (1) ES2296104T3 (da)
FR (1) FR2867780B1 (da)
GE (1) GEP20074035B (da)
HK (1) HK1079775A1 (da)
HR (1) HRP20070518T8 (da)
MA (1) MA27547A1 (da)
MX (1) MXPA05002985A (da)
MY (1) MY136910A (da)
NO (1) NO20051367L (da)
NZ (1) NZ538935A (da)
PL (1) PL1593682T3 (da)
PT (1) PT1593682E (da)
RS (1) RS50547B (da)
SG (1) SG115741A1 (da)
SI (1) SI1593682T1 (da)
UA (1) UA83638C2 (da)
ZA (1) ZA200502316B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2867780B1 (fr) * 2004-03-19 2006-05-19 Servier Lab Nouveaux derives de 4-oxo-4,6,7,8-tetrahydropyrrolo (1,2-a) pyrazine-6-carboxamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN101092372B (zh) * 2006-06-20 2011-09-21 上海药明康德新药开发有限公司 光学活性α-氨基庚二酸酯或单酯的合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2701951B1 (fr) * 1993-02-24 1995-06-09 Adir Nouveaux derives peptidiques de l'acide boronique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
US6156540A (en) * 1993-12-22 2000-12-05 Human Genome Sciences, Inc. Thrombin inhibitor
IL112795A (en) * 1994-03-04 2001-01-28 Astrazeneca Ab Derivatives of peptides as antithrombotic drugs, their preparation, and pharmaceutical preparations containing them
JP2000512616A (ja) * 1996-02-22 2000-09-26 メルク エンド カンパニー インコーポレーテッド ピリジノントロンビンインヒビター
UA58636C2 (uk) * 1999-06-04 2003-08-15 Мерк Енд Ко., Інк. Піразинонові інгібітори тромбіну, фармацевтична композиція, спосіб інгібування утворення тромбів у крові, спосіб лікування станів, пов'язаних із тромбоутворенням
FR2795072B1 (fr) * 1999-06-15 2001-07-27 Adir Nouveaux derives bicycliques d'amino-pyrazinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2818277B1 (fr) * 2000-12-14 2003-01-24 Servier Lab Nouveaux derives bicycliques d'amino-pyrazinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2867780B1 (fr) * 2004-03-19 2006-05-19 Servier Lab Nouveaux derives de 4-oxo-4,6,7,8-tetrahydropyrrolo (1,2-a) pyrazine-6-carboxamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
US7498330B2 (en) 2009-03-03
US20090131668A1 (en) 2009-05-21
EA008688B1 (ru) 2007-06-29
DE602005003161T2 (de) 2008-09-18
NZ538935A (en) 2005-09-30
EP1593682A2 (fr) 2005-11-09
PT1593682E (pt) 2007-12-06
CY1107157T1 (el) 2012-10-24
HK1079775A1 (en) 2006-04-13
KR20060044455A (ko) 2006-05-16
JP2005272467A (ja) 2005-10-06
CN1297558C (zh) 2007-01-31
EP1593682B1 (fr) 2007-11-07
RS50547B (sr) 2010-05-07
NO20051367D0 (no) 2005-03-16
CA2500575A1 (fr) 2005-09-19
AR048277A1 (es) 2006-04-12
MY136910A (en) 2008-11-28
KR100741236B1 (ko) 2007-07-19
DE602005003161D1 (de) 2007-12-20
BRPI0500889A (pt) 2005-11-01
MXPA05002985A (es) 2005-10-06
HRP20070518T5 (en) 2008-10-31
AU2005201198B8 (en) 2011-03-10
ZA200502316B (en) 2005-10-03
EP1593682A3 (fr) 2006-01-18
CN1680377A (zh) 2005-10-12
NO20051367L (no) 2005-09-20
SI1593682T1 (sl) 2008-02-29
FR2867780B1 (fr) 2006-05-19
FR2867780A1 (fr) 2005-09-23
UA83638C2 (ru) 2008-08-11
HRP20070518T8 (en) 2008-10-31
ATE377601T1 (de) 2007-11-15
SG115741A1 (en) 2005-10-28
EA200500379A1 (ru) 2005-10-27
AU2005201198A1 (en) 2005-10-06
GEP20074035B (en) 2007-02-12
CA2500575C (fr) 2010-06-22
PL1593682T3 (pl) 2008-03-31
ES2296104T3 (es) 2008-04-16
HRP20070518T3 (en) 2007-12-31
AU2005201198B2 (en) 2010-11-11
MA27547A1 (fr) 2005-10-03
US20050209234A1 (en) 2005-09-22

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