DK1579852T3 - Fremgangsmåde til fremstilling af lægemiddelbærerpellets - Google Patents

Fremgangsmåde til fremstilling af lægemiddelbærerpellets

Info

Publication number
DK1579852T3
DK1579852T3 DK05012416.3T DK05012416T DK1579852T3 DK 1579852 T3 DK1579852 T3 DK 1579852T3 DK 05012416 T DK05012416 T DK 05012416T DK 1579852 T3 DK1579852 T3 DK 1579852T3
Authority
DK
Denmark
Prior art keywords
drug carrier
preparing drug
carrier pellets
pellets
physiologically tolerable
Prior art date
Application number
DK05012416.3T
Other languages
English (en)
Inventor
Eva Lynenskjold
Lone Norgaard Jorgensen
Original Assignee
Alpharma Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpharma Aps filed Critical Alpharma Aps
Application granted granted Critical
Publication of DK1579852T3 publication Critical patent/DK1579852T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DK05012416.3T 2000-02-17 2001-02-19 Fremgangsmåde til fremstilling af lægemiddelbærerpellets DK1579852T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0003782.0A GB0003782D0 (en) 2000-02-17 2000-02-17 Process
EP01905936A EP1257256B1 (en) 2000-02-17 2001-02-19 Drug carrier pellet production process

Publications (1)

Publication Number Publication Date
DK1579852T3 true DK1579852T3 (da) 2010-09-27

Family

ID=9885881

Family Applications (2)

Application Number Title Priority Date Filing Date
DK01905936T DK1257256T3 (da) 2000-02-17 2001-02-19 Fremgangsmåde til fremstilling af lægemiddelbærepelleter
DK05012416.3T DK1579852T3 (da) 2000-02-17 2001-02-19 Fremgangsmåde til fremstilling af lægemiddelbærerpellets

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK01905936T DK1257256T3 (da) 2000-02-17 2001-02-19 Fremgangsmåde til fremstilling af lægemiddelbærepelleter

Country Status (9)

Country Link
US (2) US7338668B2 (da)
EP (2) EP1579852B1 (da)
AT (2) ATE468843T1 (da)
AU (1) AU784105B2 (da)
CA (1) CA2396376C (da)
DE (2) DE60113509T2 (da)
DK (2) DK1257256T3 (da)
GB (1) GB0003782D0 (da)
WO (1) WO2001060338A1 (da)

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GB9825033D0 (en) * 1998-11-13 1999-01-13 Nycomed Pharma As Process
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US8071133B2 (en) * 2001-08-20 2011-12-06 Stiefel Laboratories, Inc. Oral dosage forms of water insoluble drugs and methods of making the same
US20040091528A1 (en) * 2002-11-12 2004-05-13 Yamanouchi Pharma Technologies, Inc. Soluble drug extended release system
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
CZ20032854A3 (cs) * 2003-10-17 2005-05-18 Pliva - Lachema A.S. Způsob přípravy dávkových jednotek pevné lékové formy obsahujících jako účinnou látku sodnou sůl warfarinu
ES2523148T3 (es) * 2004-05-24 2014-11-21 Takeda Nycomed As Material en forma de partículas que comprende un compuesto que contiene calcio y un alcohol de azúcar
WO2006082499A1 (en) 2005-02-03 2006-08-10 Nycomed Pharma As Melt granulation of a composition containing a calcium-containing compound
WO2006092727A2 (en) * 2005-03-04 2006-09-08 Nycomed Pharma As Process for the production of calcium compositions in a continuous fluid bed
UA95093C2 (uk) * 2005-12-07 2011-07-11 Нікомед Фарма Ас Спосіб одержання кальцієвмісної сполуки
WO2007065440A1 (en) * 2005-12-07 2007-06-14 Nycomed Pharma As Pre-compacted calcium-containing compositions
TR200605624A2 (tr) * 2006-10-10 2008-05-21 Nobel İlaç Sanayi̇ Ve Ti̇caret Aş. Farmasötik dozaj şekli
WO2009072334A1 (ja) * 2007-12-03 2009-06-11 Tomita Pharmaceutical Co., Ltd. 製剤用核粒子
DE102008004893A1 (de) * 2008-01-17 2009-07-23 Add Technologies Ltd. Trägerpellets, Verfahren zu deren Herstellung und deren Verwendung
RU2010143901A (ru) * 2008-03-28 2012-05-10 Бёрингер Ингельхайм Интернациональ Гмбх (De) Способ получения композиций дабигатрана для перорального введения
NZ589746A (en) 2008-07-14 2012-10-26 Boehringer Ingelheim Int Method for manufacturing medicinal compounds containing dabigatran
JP5472756B2 (ja) 2008-10-02 2014-04-16 マイラン・インク 多層接着ラミネートの作製方法
JP2013510072A (ja) 2008-11-11 2013-03-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 従来のワルファリン治療に対して安全性プロフィールが改善されたダビガトランエテキシレートまたはその塩を使用して血栓症を治療または予防するための方法
WO2010059506A1 (en) * 2008-11-20 2010-05-27 Mallinckrodt Baker, Inc. Directly compressible high functionality granular dibasic calcium phosphate based co-processed excipient
EP2608773A4 (en) 2010-08-24 2014-03-05 Univ Rutgers FORMULATION AND MANUFACTURE OF PHARMACEUTICAL PRODUCTS BY IMPREGNATING ON POROUS SUBSTRATES
JP5917964B2 (ja) * 2012-03-19 2016-05-18 富士ゼロックス株式会社 錠剤、錠剤の製造方法、錠剤管理装置、錠剤照合装置及びプログラム
PL2872121T3 (pl) 2012-07-12 2019-02-28 SpecGx LLC Kompozycje farmaceutyczne o przedłużonym uwalnianiu, zniechęcające do nadużywania
BR112022023307A2 (pt) 2020-05-18 2022-12-20 Orexo Ab Composição farmacêutica para entrega de fármacos
WO2022241159A1 (en) * 2021-05-12 2022-11-17 Spectrix Therapeutics, LLC Compositions and methods
EP4236921A1 (en) 2021-11-25 2023-09-06 Orexo AB Pharmaceutical composition comprising adrenaline

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US3833392A (en) * 1971-08-09 1974-09-03 Westinghouse Electric Corp Coating composition and method for preparing water-soluble cellulosic polymer coating compositions for coating fluorescent tubes
AU530410B2 (en) 1978-02-21 1983-07-14 Sintef Preparing aqueous emulsions
EP0028796B1 (de) * 1979-11-13 1983-07-13 Bayer Ag Beschichtete magnetische Metall- und Legierungspigmente, Verfahren zu ihrer Herstellung und ihre Verwendung
US4622057A (en) * 1983-03-02 1986-11-11 Corning Glass Works Process for making thick-walled ceramic bodies from synthetic micas
EP0439373A1 (en) 1990-01-26 1991-07-31 Pfizer Inc. Low density agglomerate utilizing a carbohydrate binder
US5643591A (en) * 1991-01-16 1997-07-01 Fmc Corporation Solid dosage forms
US5397576A (en) * 1992-09-23 1995-03-14 Hoffmann-La Roche Inc. Spray triturated micronutrient compositions
JP2700141B2 (ja) * 1993-09-17 1998-01-19 富士化学工業株式会社 リン酸水素カルシウム及びその製法並びにそれを用いた賦形剤
US5486507A (en) * 1994-01-14 1996-01-23 Fuisz Technologies Ltd. Porous particle aggregate and method therefor
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
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ES2210321T3 (es) * 1994-12-19 2004-07-01 Daiichi Pharmaceutical Co., Ltd. Preparacion granular de liberacion prolongada y procedimiento de produccion.
US6395303B1 (en) * 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
GB9519094D0 (en) * 1995-09-19 1995-11-22 Warwick Int Group Granulated active with controlled release
JP4027535B2 (ja) * 1998-05-26 2007-12-26 エーザイ・アール・アンド・ディー・マネジメント株式会社 脂溶性薬物を含有した粉末

Also Published As

Publication number Publication date
US7338668B2 (en) 2008-03-04
US20030211168A1 (en) 2003-11-13
DE60142259D1 (de) 2010-07-08
GB0003782D0 (en) 2000-04-05
EP1579852A2 (en) 2005-09-28
ATE468843T1 (de) 2010-06-15
EP1579852B1 (en) 2010-05-26
DE60113509T2 (de) 2006-06-22
DK1257256T3 (da) 2005-12-19
AU3390001A (en) 2001-08-27
CA2396376A1 (en) 2001-08-23
WO2001060338A1 (en) 2001-08-23
DE60113509D1 (de) 2005-10-27
EP1257256B1 (en) 2005-09-21
US20090017125A1 (en) 2009-01-15
EP1579852A3 (en) 2007-07-25
CA2396376C (en) 2010-04-27
ATE304843T1 (de) 2005-10-15
EP1257256A1 (en) 2002-11-20
AU784105B2 (en) 2006-02-02

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