DK156716C - Fremgangsmaade til fremstilling af 1-fluorerede vitamin d-forbindelser eller 1-fluor-5,6-trans vitamin d-forbindelser eller 1-fluor-3,5-cyclovitamin d-forbindelser - Google Patents
Fremgangsmaade til fremstilling af 1-fluorerede vitamin d-forbindelser eller 1-fluor-5,6-trans vitamin d-forbindelser eller 1-fluor-3,5-cyclovitamin d-forbindelserInfo
- Publication number
- DK156716C DK156716C DK127580A DK127580A DK156716C DK 156716 C DK156716 C DK 156716C DK 127580 A DK127580 A DK 127580A DK 127580 A DK127580 A DK 127580A DK 156716 C DK156716 C DK 156716C
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- vitamin
- fluor
- fluored
- cyclovitamin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92827978 | 1978-07-26 | ||
US05/928,279 US4188345A (en) | 1978-07-26 | 1978-07-26 | Fluorovitamin D compounds and processes for their preparation |
PCT/US1979/000529 WO1980000339A1 (fr) | 1978-07-26 | 1979-07-24 | Procede de preparation de composes de vitamine d fluoree en position 1 |
US7900529 | 1979-07-24 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK127580A DK127580A (da) | 1980-03-25 |
DK156716B DK156716B (da) | 1989-09-25 |
DK156716C true DK156716C (da) | 1990-02-19 |
Family
ID=25456012
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK127480A DK154211C (da) | 1978-07-26 | 1980-03-25 | Fremgangsmaade til fremstilling af 25-fluorsubstituerede vitamin d- og 5,6-trans-vitamin d forbindelser |
DK127580A DK156716C (da) | 1978-07-26 | 1980-03-25 | Fremgangsmaade til fremstilling af 1-fluorerede vitamin d-forbindelser eller 1-fluor-5,6-trans vitamin d-forbindelser eller 1-fluor-3,5-cyclovitamin d-forbindelser |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK127480A DK154211C (da) | 1978-07-26 | 1980-03-25 | Fremgangsmaade til fremstilling af 25-fluorsubstituerede vitamin d- og 5,6-trans-vitamin d forbindelser |
Country Status (14)
Country | Link |
---|---|
US (1) | US4188345A (fr) |
JP (2) | JPS6312868B2 (fr) |
AU (1) | AU521131B2 (fr) |
BE (1) | BE877918A (fr) |
CH (2) | CH641445A5 (fr) |
DK (2) | DK154211C (fr) |
FR (1) | FR2433514B1 (fr) |
GB (1) | GB2026494B (fr) |
IE (1) | IE48463B1 (fr) |
IL (1) | IL57801A (fr) |
NL (2) | NL7920016A (fr) |
NZ (1) | NZ190939A (fr) |
SE (2) | SE8001747L (fr) |
WO (2) | WO1980000339A1 (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4196133A (en) * | 1979-03-05 | 1980-04-01 | Wisconsin Alumni Research Foundation | 24,24-Difluoro-25-hydroxycholecalciferol |
US4410515A (en) * | 1981-04-01 | 1983-10-18 | Massachusetts General Hospital | Vitamin D glycosides and a method of use |
WO1984000107A1 (fr) * | 1982-06-30 | 1984-01-19 | Massachusetts Gen Hospital | Glycosides de la vitamine d |
US4428946A (en) * | 1982-07-26 | 1984-01-31 | Wisconsin Alumni Research Foundation | Method of preventing milk fever in dairy cattle |
US4448721A (en) * | 1982-09-20 | 1984-05-15 | Wisconsin Alumni Research Foundation | Hydroxyvitamin D2 compounds and process for preparing same |
GB2145091B (en) * | 1983-08-18 | 1987-08-12 | Wisconsin Alumni Res Found | Vitamin d3 derivatives |
US4661294A (en) * | 1985-03-18 | 1987-04-28 | The General Hospital Corporation | Biologically active 1-thio derivatives of vitamin D |
US5401731A (en) * | 1989-06-29 | 1995-03-28 | Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Productionsaktieselskab) | Vitamin D analogues |
TR25295A (tr) * | 1992-02-26 | 1993-01-01 | Simfer Dayanikli Tueketim Mamu | Kati yakit yakan sobalar icin yanma havasi ön isitma sistemi |
US5384314B1 (en) * | 1994-03-11 | 1997-08-05 | Hoffmann La Roche | 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol |
WO1997011053A1 (fr) * | 1995-09-21 | 1997-03-27 | Wisconsin Alumni Research Foundation | Derives de calcitriol et leurs utilisations |
US5952317A (en) * | 1995-09-21 | 1999-09-14 | Wisconsin Alumni Research Foundation | Calcitriol derivatives and their uses |
US5976784A (en) * | 1996-09-20 | 1999-11-02 | Wisconsin Alumni Research Foundation | Calcitriol derivatives and their uses |
US6100294A (en) * | 1997-05-16 | 2000-08-08 | Women And Infants Hospital | Cyclic ether vitamin D3 compounds, 1α(OH) 3-epi-vitamin D3 compounds and uses thereof |
US7648973B2 (en) * | 2006-04-06 | 2010-01-19 | Wisconsin Alumni Research Foundation | 2-methylene-1α,25-dihydroxy-19,21-dinorvitamin D3 analogs and uses thereof |
EP2001860A2 (fr) * | 2006-04-06 | 2008-12-17 | Wisconsin Alumni Research Foundation | Analogues de la 19-nor-vitamine d présentant un noyau 1,2, ou 3,2 hétérocyclique |
CA2646911A1 (fr) | 2006-04-06 | 2008-03-27 | Hector F. Deluca | Analogues de la 1alpha,25-dihydroxy-19,26,27-trinor vitamine d substituee en position 2 et leurs utilisations |
EP2001841B1 (fr) * | 2006-04-06 | 2012-06-13 | Wisconsin Alumni Research Foundation | Composes analogues a la 2-methylene-1 alpha-hydroxy-18,19,21-trinorvitamine d3 et leurs utilisations |
NZ570814A (en) * | 2006-04-06 | 2011-11-25 | Wisconsin Alumni Res Found | 2-methylene-1alpha-hydroxy-19,21-dinorvitamin D3 analogs and uses thereof |
EP2021321B1 (fr) * | 2006-04-06 | 2012-06-20 | Wisconsin Alumni Research Foundation | 2-méthylène-1-alpha,25-dihydroxy-18,19,21-trinorvitamine d3 et ses utilisations |
ATE496885T1 (de) * | 2006-04-10 | 2011-02-15 | Wisconsin Alumni Res Found | 1-alpha-hydroxy-2-(3'-hydroxypropyliden)-19-nor vitamin-d-verbindungen mit einer 1,1- dimethylpropyl-seitenkette |
US8377913B2 (en) * | 2007-11-20 | 2013-02-19 | Abbvie Inc. | Vitamin D receptor activators and methods of making |
US8814007B2 (en) | 2010-12-31 | 2014-08-26 | Medline Industries, Inc. | Dispenser with directional flow controlling flange and corresponding systems |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3833622A (en) * | 1969-03-17 | 1974-09-03 | Upjohn Co | Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds |
US4069321A (en) * | 1975-10-14 | 1978-01-17 | Merck & Co., Inc. | Blocked cholecalciferol and dihydrotachysterol 3 derivatives |
-
1978
- 1978-07-26 US US05/928,279 patent/US4188345A/en not_active Expired - Lifetime
-
1979
- 1979-07-06 NZ NZ190939A patent/NZ190939A/xx unknown
- 1979-07-13 IL IL57801A patent/IL57801A/xx not_active IP Right Cessation
- 1979-07-24 CH CH249680A patent/CH641445A5/de not_active IP Right Cessation
- 1979-07-24 NL NL7920016A patent/NL7920016A/nl unknown
- 1979-07-24 JP JP54501224A patent/JPS6312868B2/ja not_active Expired
- 1979-07-24 NL NL7920012A patent/NL7920012A/nl unknown
- 1979-07-24 WO PCT/US1979/000529 patent/WO1980000339A1/fr unknown
- 1979-07-24 CH CH2497/80A patent/CH650237A5/de not_active IP Right Cessation
- 1979-07-24 WO PCT/US1979/000528 patent/WO1980000338A1/fr unknown
- 1979-07-24 JP JP54501218A patent/JPS6312867B2/ja not_active Expired
- 1979-07-25 AU AU49206/79A patent/AU521131B2/en not_active Ceased
- 1979-07-26 GB GB7926135A patent/GB2026494B/en not_active Expired
- 1979-07-26 BE BE0/196477A patent/BE877918A/fr not_active IP Right Cessation
- 1979-07-26 FR FR7919368A patent/FR2433514B1/fr not_active Expired
- 1979-08-08 IE IE1496/79A patent/IE48463B1/en not_active IP Right Cessation
-
1980
- 1980-03-05 SE SE8001747A patent/SE8001747L/xx unknown
- 1980-03-05 SE SE8001746A patent/SE8001746L/xx unknown
- 1980-03-25 DK DK127480A patent/DK154211C/da not_active IP Right Cessation
- 1980-03-25 DK DK127580A patent/DK156716C/da not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1980000338A1 (fr) | 1980-03-06 |
GB2026494A (en) | 1980-02-06 |
JPS6312867B2 (fr) | 1988-03-23 |
DK127580A (da) | 1980-03-25 |
DK154211C (da) | 1989-03-13 |
AU4920679A (en) | 1980-01-31 |
FR2433514A1 (fr) | 1980-03-14 |
CH650237A5 (de) | 1985-07-15 |
DK127480A (da) | 1980-03-25 |
GB2026494B (en) | 1982-12-15 |
IL57801A0 (en) | 1979-11-30 |
DK154211B (da) | 1988-10-24 |
NL7920012A (nl) | 1980-05-30 |
JPS55500428A (fr) | 1980-07-17 |
CH641445A5 (de) | 1984-02-29 |
WO1980000339A1 (fr) | 1980-03-06 |
IE791496L (en) | 1980-01-26 |
IL57801A (en) | 1984-03-30 |
SE8001746L (sv) | 1980-03-05 |
JPS6312868B2 (fr) | 1988-03-23 |
NL7920016A (nl) | 1980-05-30 |
BE877918A (fr) | 1979-11-16 |
IE48463B1 (en) | 1985-01-23 |
FR2433514B1 (fr) | 1986-05-23 |
NZ190939A (en) | 1982-09-07 |
JPS55500430A (fr) | 1980-07-17 |
SE8001747L (sv) | 1980-03-05 |
AU521131B2 (en) | 1982-03-18 |
DK156716B (da) | 1989-09-25 |
US4188345A (en) | 1980-02-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |