BE877918A - Composes fluores ayant la structure de la vitamine d - Google Patents

Composes fluores ayant la structure de la vitamine d

Info

Publication number
BE877918A
BE877918A BE0/196477A BE196477A BE877918A BE 877918 A BE877918 A BE 877918A BE 0/196477 A BE0/196477 A BE 0/196477A BE 196477 A BE196477 A BE 196477A BE 877918 A BE877918 A BE 877918A
Authority
BE
Belgium
Prior art keywords
vitamin
fluorine compounds
fluorine
compounds
Prior art date
Application number
BE0/196477A
Other languages
English (en)
Inventor
B Onisko
J Napoli
H Schnoes
Luca H De
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of BE877918A publication Critical patent/BE877918A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials
BE0/196477A 1978-07-26 1979-07-26 Composes fluores ayant la structure de la vitamine d BE877918A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/928,279 US4188345A (en) 1978-07-26 1978-07-26 Fluorovitamin D compounds and processes for their preparation

Publications (1)

Publication Number Publication Date
BE877918A true BE877918A (fr) 1979-11-16

Family

ID=25456012

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/196477A BE877918A (fr) 1978-07-26 1979-07-26 Composes fluores ayant la structure de la vitamine d

Country Status (14)

Country Link
US (1) US4188345A (fr)
JP (2) JPS6312868B2 (fr)
AU (1) AU521131B2 (fr)
BE (1) BE877918A (fr)
CH (2) CH641445A5 (fr)
DK (2) DK154211C (fr)
FR (1) FR2433514B1 (fr)
GB (1) GB2026494B (fr)
IE (1) IE48463B1 (fr)
IL (1) IL57801A (fr)
NL (2) NL7920016A (fr)
NZ (1) NZ190939A (fr)
SE (2) SE8001746L (fr)
WO (2) WO1980000339A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196133A (en) * 1979-03-05 1980-04-01 Wisconsin Alumni Research Foundation 24,24-Difluoro-25-hydroxycholecalciferol
US4410515A (en) * 1981-04-01 1983-10-18 Massachusetts General Hospital Vitamin D glycosides and a method of use
JPS59501264A (ja) * 1982-06-30 1984-07-19 マサチユ−セツツ　ゼネラル　ホスピタル ビタミンｄグリコシド類
US4428946A (en) * 1982-07-26 1984-01-31 Wisconsin Alumni Research Foundation Method of preventing milk fever in dairy cattle
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
GB2145091B (en) * 1983-08-18 1987-08-12 Wisconsin Alumni Res Found Vitamin d3 derivatives
US4661294A (en) * 1985-03-18 1987-04-28 The General Hospital Corporation Biologically active 1-thio derivatives of vitamin D
US5401731A (en) * 1989-06-29 1995-03-28 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Productionsaktieselskab) Vitamin D analogues
TR25295A (tr) * 1992-02-26 1993-01-01 Simfer Dayanikli Tueketim Mamu Kati yakit yakan sobalar icin yanma havasi ön isitma sistemi
US5384314B1 (en) * 1994-03-11 1997-08-05 Hoffmann La Roche 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
AU717238B2 (en) * 1995-09-21 2000-03-23 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
CA2289209C (fr) 1997-05-16 2006-07-25 Women & Infants Hospital Composes de vitamine d3 a ether cyclique et composes de 1.alpha.(oh) 3-epi-vitamine d3, et utilisation desdits composes
AU2007298673A1 (en) 2006-04-06 2008-03-27 Wisconsin Alumni Research Foundation 2- substituted-1alpha, 25-dihydroxy-19,26,27-trinor vitamin D analogs and uses thereof
EP2001841B1 (fr) * 2006-04-06 2012-06-13 Wisconsin Alumni Research Foundation Composes analogues a la 2-methylene-1 alpha-hydroxy-18,19,21-trinorvitamine d3 et leurs utilisations
WO2008035207A2 (fr) * 2006-04-06 2008-03-27 Wisconsin Alumni Research Foundation Composés analogues à la 2-méthylène-1alpha-hydroxy-19,21-dinorvitamine d3 et leurs utilisations
WO2007118198A2 (fr) * 2006-04-06 2007-10-18 Wisconsin Alumni Research Foundation ANALOGUES DE LA 2-MÉTHYLÈNE-1α,25-DIHYDROXY-19,21-DINOR-VITAMINE D3 ET LEURS UTILISATIONS
US7538098B2 (en) * 2006-04-06 2009-05-26 Wisconsin Alumni Research Foundation 19-nor-vitamin D analogs with 1,2 or 3,2 heterocyclic ring
WO2008125901A2 (fr) * 2006-04-06 2008-10-23 Wisconsin Alumni Research Foundation 2-méthylène-1-alpha,25-dihydroxy-18,19,21-trinorvitamine d3 et ses utilisations
US7763598B2 (en) * 2006-04-10 2010-07-27 Wisconsin Alumni Research Foundation 1α-hydroxy-2-(3′-hydroxypropylidene)-19-nor-vitamin D compounds with a 1,1-dimethylpropyl side chain
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
US8814007B2 (en) 2010-12-31 2014-08-26 Medline Industries, Inc. Dispenser with directional flow controlling flange and corresponding systems

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives

Also Published As

Publication number Publication date
WO1980000338A1 (fr) 1980-03-06
JPS55500430A (fr) 1980-07-17
NL7920016A (nl) 1980-05-30
CH650237A5 (de) 1985-07-15
NZ190939A (en) 1982-09-07
FR2433514A1 (fr) 1980-03-14
DK154211B (da) 1988-10-24
JPS55500428A (fr) 1980-07-17
IE791496L (en) 1980-01-26
SE8001746L (sv) 1980-03-05
AU521131B2 (en) 1982-03-18
GB2026494B (en) 1982-12-15
WO1980000339A1 (fr) 1980-03-06
DK127580A (da) 1980-03-25
DK127480A (da) 1980-03-25
CH641445A5 (de) 1984-02-29
FR2433514B1 (fr) 1986-05-23
DK154211C (da) 1989-03-13
JPS6312867B2 (fr) 1988-03-23
DK156716C (da) 1990-02-19
SE8001747L (sv) 1980-03-05
JPS6312868B2 (fr) 1988-03-23
DK156716B (da) 1989-09-25
IE48463B1 (en) 1985-01-23
IL57801A0 (en) 1979-11-30
IL57801A (en) 1984-03-30
AU4920679A (en) 1980-01-31
GB2026494A (en) 1980-02-06
US4188345A (en) 1980-02-12
NL7920012A (nl) 1980-05-30

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: WISCONSIN ALUMNI RESEARCH FOUNDATION

Effective date: 19930731