FR2433514A1 - Composes fluores ayant la structure de la vitamine d - Google Patents

Composes fluores ayant la structure de la vitamine d

Info

Publication number
FR2433514A1
FR2433514A1 FR7919368A FR7919368A FR2433514A1 FR 2433514 A1 FR2433514 A1 FR 2433514A1 FR 7919368 A FR7919368 A FR 7919368A FR 7919368 A FR7919368 A FR 7919368A FR 2433514 A1 FR2433514 A1 FR 2433514A1
Authority
FR
France
Prior art keywords
vitamin
fluorinated compounds
fluorinated
compounds
fluorovitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7919368A
Other languages
English (en)
Other versions
FR2433514B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of FR2433514A1 publication Critical patent/FR2433514A1/fr
Application granted granted Critical
Publication of FR2433514B1 publication Critical patent/FR2433514B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Abstract

L'invention concerne l'industrie pharmaceutique. Elle a pour objet une fluorovitamine D de formule (I) ou (II) :
FR7919368A 1978-07-26 1979-07-26 Composes fluores ayant la structure de la vitamine d Expired FR2433514B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/928,279 US4188345A (en) 1978-07-26 1978-07-26 Fluorovitamin D compounds and processes for their preparation

Publications (2)

Publication Number Publication Date
FR2433514A1 true FR2433514A1 (fr) 1980-03-14
FR2433514B1 FR2433514B1 (fr) 1986-05-23

Family

ID=25456012

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7919368A Expired FR2433514B1 (fr) 1978-07-26 1979-07-26 Composes fluores ayant la structure de la vitamine d

Country Status (14)

Country Link
US (1) US4188345A (fr)
JP (2) JPS6312868B2 (fr)
AU (1) AU521131B2 (fr)
BE (1) BE877918A (fr)
CH (2) CH641445A5 (fr)
DK (2) DK154211C (fr)
FR (1) FR2433514B1 (fr)
GB (1) GB2026494B (fr)
IE (1) IE48463B1 (fr)
IL (1) IL57801A (fr)
NL (2) NL7920016A (fr)
NZ (1) NZ190939A (fr)
SE (2) SE8001746L (fr)
WO (2) WO1980000339A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196133A (en) * 1979-03-05 1980-04-01 Wisconsin Alumni Research Foundation 24,24-Difluoro-25-hydroxycholecalciferol
US4410515A (en) * 1981-04-01 1983-10-18 Massachusetts General Hospital Vitamin D glycosides and a method of use
JPS59501264A (ja) * 1982-06-30 1984-07-19 マサチユ−セツツ　ゼネラル　ホスピタル ビタミンｄグリコシド類
US4428946A (en) * 1982-07-26 1984-01-31 Wisconsin Alumni Research Foundation Method of preventing milk fever in dairy cattle
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
GB2145091B (en) * 1983-08-18 1987-08-12 Wisconsin Alumni Res Found Vitamin d3 derivatives
US4661294A (en) * 1985-03-18 1987-04-28 The General Hospital Corporation Biologically active 1-thio derivatives of vitamin D
US5401731A (en) * 1989-06-29 1995-03-28 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Productionsaktieselskab) Vitamin D analogues
TR25295A (tr) * 1992-02-26 1993-01-01 Simfer Dayanikli Tueketim Mamu Kati yakit yakan sobalar icin yanma havasi ön isitma sistemi
US5384314B1 (en) * 1994-03-11 1997-08-05 Hoffmann La Roche 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
AU717238B2 (en) * 1995-09-21 2000-03-23 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
CA2289209C (fr) 1997-05-16 2006-07-25 Women & Infants Hospital Composes de vitamine d3 a ether cyclique et composes de 1.alpha.(oh) 3-epi-vitamine d3, et utilisation desdits composes
AU2007298673A1 (en) 2006-04-06 2008-03-27 Wisconsin Alumni Research Foundation 2- substituted-1alpha, 25-dihydroxy-19,26,27-trinor vitamin D analogs and uses thereof
EP2001841B1 (fr) * 2006-04-06 2012-06-13 Wisconsin Alumni Research Foundation Composes analogues a la 2-methylene-1 alpha-hydroxy-18,19,21-trinorvitamine d3 et leurs utilisations
WO2008035207A2 (fr) * 2006-04-06 2008-03-27 Wisconsin Alumni Research Foundation Composés analogues à la 2-méthylène-1alpha-hydroxy-19,21-dinorvitamine d3 et leurs utilisations
WO2007118198A2 (fr) * 2006-04-06 2007-10-18 Wisconsin Alumni Research Foundation ANALOGUES DE LA 2-MÉTHYLÈNE-1α,25-DIHYDROXY-19,21-DINOR-VITAMINE D3 ET LEURS UTILISATIONS
US7538098B2 (en) * 2006-04-06 2009-05-26 Wisconsin Alumni Research Foundation 19-nor-vitamin D analogs with 1,2 or 3,2 heterocyclic ring
WO2008125901A2 (fr) * 2006-04-06 2008-10-23 Wisconsin Alumni Research Foundation 2-méthylène-1-alpha,25-dihydroxy-18,19,21-trinorvitamine d3 et ses utilisations
US7763598B2 (en) * 2006-04-10 2010-07-27 Wisconsin Alumni Research Foundation 1α-hydroxy-2-(3′-hydroxypropylidene)-19-nor-vitamin D compounds with a 1,1-dimethylpropyl side chain
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
US8814007B2 (en) 2010-12-31 2014-08-26 Medline Industries, Inc. Dispenser with directional flow controlling flange and corresponding systems

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives

Also Published As

Publication number Publication date
WO1980000338A1 (fr) 1980-03-06
JPS55500430A (fr) 1980-07-17
NL7920016A (nl) 1980-05-30
CH650237A5 (de) 1985-07-15
NZ190939A (en) 1982-09-07
DK154211B (da) 1988-10-24
JPS55500428A (fr) 1980-07-17
IE791496L (en) 1980-01-26
SE8001746L (sv) 1980-03-05
AU521131B2 (en) 1982-03-18
GB2026494B (en) 1982-12-15
WO1980000339A1 (fr) 1980-03-06
DK127580A (da) 1980-03-25
DK127480A (da) 1980-03-25
CH641445A5 (de) 1984-02-29
FR2433514B1 (fr) 1986-05-23
DK154211C (da) 1989-03-13
JPS6312867B2 (fr) 1988-03-23
DK156716C (da) 1990-02-19
SE8001747L (sv) 1980-03-05
BE877918A (fr) 1979-11-16
JPS6312868B2 (fr) 1988-03-23
DK156716B (da) 1989-09-25
IE48463B1 (en) 1985-01-23
IL57801A0 (en) 1979-11-30
IL57801A (en) 1984-03-30
AU4920679A (en) 1980-01-31
GB2026494A (en) 1980-02-06
US4188345A (en) 1980-02-12
NL7920012A (nl) 1980-05-30

Similar Documents

Publication Publication Date Title
FR2433514A1 (fr) Composes fluores ayant la structure de la vitamine d
FR2442849A1 (fr)
FR2433515A1 (fr) Acides pyrrolidinecarboxyliques-2 utiles comme antihypertenseurs
FR2369297A1 (fr) Nouveaux esters d'acides androstadiene-17-carboxyliques
FR2369241A2 (fr) Nouvelles substances a action physiologique deriv
FR2435478A1 (fr) Derives spiro (indoline naphtoxazine) et leurs applications photochroniques
FR2432511A1 (fr) Derives triazoliques, leur preparation et leur application en tant que medicaments
FR2370753A1 (fr) Derives du glucofurannose et leur application therapeutique
FR2391723A1 (fr) Composition therapeutique a base de cetone aliphatique pour le traitement des ulceres peptiques
FR2390433A1 (fr) Composes utiles pour la preparation de derives d'acide penicillanique
FR2444681A1 (fr) Nouvelles 1,4-dihydropyridines, leur preparation et leur application comme medicaments
FR2373533A1 (fr) Benzimidazoles 2-substitues
FR2417504A1 (fr) Composes d'imidazole
FR2389623A1 (fr)
FR2426060A1 (fr) Poly(ethers chloroalkyleniques) a terminaison hydroxy incolores
FR2374039A1 (fr) Compositions contenant un derive de l'acide salicylique et applications a titre de medicament
FR2422405A1 (fr) Nouveaux medicaments constitues de derives de l'acide p-aminobenzoique
FR2375239A1 (fr) Derives d'acide 7-amino-8-oxo-3-oxa-1-azabicyclo-(4.2.0)octane-2-carboxylique
FR2426468A1 (fr) Composes de type acide p-aminobenzoique-n-d-xyloside utiles comme medicaments
FR2394514A1 (fr) Nouvel acide cyclohexanecarboxylique et ses derives
FR2392958A1 (fr) Nouveaux amino-acides fluores utiles comme medicament
SE8100846L (sv) Antirinovirusmedel
FR2421616A1 (fr) Nouveaux medicaments constitues de derives de l'acide o-aminobenzoique
FR2367761A1 (fr) Derives piperidylideniques de benzo-xanthenes,
OA07101A (fr) Acide dicarboxylique estérifié de formule générale.

Legal Events

Date Code Title Description
ST Notification of lapse