NL7920016A - Werkwijze ter bereiding van in de zijketen gefluoreerde vitamine d verbindingen. - Google Patents

Werkwijze ter bereiding van in de zijketen gefluoreerde vitamine d verbindingen. Download PDF

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Publication number
NL7920016A
NL7920016A NL7920016A NL7920016A NL7920016A NL 7920016 A NL7920016 A NL 7920016A NL 7920016 A NL7920016 A NL 7920016A NL 7920016 A NL7920016 A NL 7920016A NL 7920016 A NL7920016 A NL 7920016A
Authority
NL
Netherlands
Prior art keywords
hydroxy
fluorine
vitamin
compounds
acyl
Prior art date
Application number
NL7920016A
Other languages
English (en)
Dutch (nl)
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of NL7920016A publication Critical patent/NL7920016A/nl

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7920016A 1978-07-26 1979-07-24 Werkwijze ter bereiding van in de zijketen gefluoreerde vitamine d verbindingen. NL7920016A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/928,279 US4188345A (en) 1978-07-26 1978-07-26 Fluorovitamin D compounds and processes for their preparation
US92827978 1978-07-26

Publications (1)

Publication Number Publication Date
NL7920016A true NL7920016A (nl) 1980-05-30

Family

ID=25456012

Family Applications (2)

Application Number Title Priority Date Filing Date
NL7920012A NL7920012A (nl) 1978-07-26 1979-07-24 Werkwijze ter bereiding van 1-gefluoreerde vitamine d verbindingen.
NL7920016A NL7920016A (nl) 1978-07-26 1979-07-24 Werkwijze ter bereiding van in de zijketen gefluoreerde vitamine d verbindingen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL7920012A NL7920012A (nl) 1978-07-26 1979-07-24 Werkwijze ter bereiding van 1-gefluoreerde vitamine d verbindingen.

Country Status (14)

Country Link
US (1) US4188345A (fr)
JP (2) JPS6312867B2 (fr)
AU (1) AU521131B2 (fr)
BE (1) BE877918A (fr)
CH (2) CH641445A5 (fr)
DK (2) DK154211C (fr)
FR (1) FR2433514B1 (fr)
GB (1) GB2026494B (fr)
IE (1) IE48463B1 (fr)
IL (1) IL57801A (fr)
NL (2) NL7920012A (fr)
NZ (1) NZ190939A (fr)
SE (2) SE8001747L (fr)
WO (2) WO1980000338A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196133A (en) * 1979-03-05 1980-04-01 Wisconsin Alumni Research Foundation 24,24-Difluoro-25-hydroxycholecalciferol
US4410515A (en) * 1981-04-01 1983-10-18 Massachusetts General Hospital Vitamin D glycosides and a method of use
EP0112332B1 (fr) * 1982-06-30 1993-06-16 The General Hospital Corporation Glycosides de la vitamine d
US4428946A (en) * 1982-07-26 1984-01-31 Wisconsin Alumni Research Foundation Method of preventing milk fever in dairy cattle
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
IT1175607B (it) * 1983-08-18 1987-07-15 Wisconsin Alumni Res Found 23,23-difluoro-25-idrossi-e 1 alfa, 25-diidrossi-vitamina d3
US4661294A (en) * 1985-03-18 1987-04-28 The General Hospital Corporation Biologically active 1-thio derivatives of vitamin D
US5401731A (en) * 1989-06-29 1995-03-28 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Productionsaktieselskab) Vitamin D analogues
TR25295A (tr) * 1992-02-26 1993-01-01 Simfer Dayanikli Tueketim Mamu Kati yakit yakan sobalar icin yanma havasi ön isitma sistemi
US5384314B1 (en) * 1994-03-11 1997-08-05 Hoffmann La Roche 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
NZ501318A (en) * 1995-09-21 2001-07-27 Wisconsin Alumni Res Found Medicaments containing 25 hydroxy vitamin D (calcitriol) derivatives
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
WO1998051678A1 (fr) 1997-05-16 1998-11-19 Women & Infants Hospital COMPOSES DE VITAMINE D3 A ETHER CYCLIQUE ET COMPOSES DE 1α(OH)3-EPI-VITAMINE D3, ET UTILISATION DESDITS COMPOSES
AU2007298652A1 (en) * 2006-04-06 2008-03-27 Wisconsin Alumni Research Foundation 2-methylene-1alpha-hydroxy-19,21-dinorvitamin D3 analogs and uses thereof
JP2010505739A (ja) * 2006-04-06 2010-02-25 ウイスコンシン アラムニ リサーチ ファンデーション ２−メチレン−１α，２５−ジヒドロキシ−１９，２１−ジノルビタミンＤ３類縁体およびその使用
JP2009532459A (ja) * 2006-04-06 2009-09-10 ウイスコンシン アラムニ リサーチ ファンデーション １，２または３，２複素環を有する１９−ノル−ビタミンｄアナログ
MX2008012913A (es) * 2006-04-06 2009-03-06 Wisconsin Alumni Res Found 2-metilen-1a,25-dihidroxi-18,19,21-trinorvitamina d3 y sus usos.
JP2009532457A (ja) * 2006-04-06 2009-09-10 ウイスコンシン アラムニ リサーチ ファンデーション ２−メチレン−１α−ヒドロキシ−１８，１９，２１−トリノルビタミンＤ３類縁体およびその使用
WO2008035228A2 (fr) 2006-04-06 2008-03-27 Wisconsin Alumni Research Foundation Analogues de la 1alpha,25-dihydroxy-19,26,27-trinor vitamine d substituée en position 2 et leurs utilisations
AU2007287263A1 (en) * 2006-04-10 2008-02-28 Wisconsin Alumni Research Foundation Lalpha-hydroxy-2- (3 ' -hydroxypropylidene) -19-nor- vitamin D compounds with a 1,1-dimethylpropyl side chain
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
US8814007B2 (en) 2010-12-31 2014-08-26 Medline Industries, Inc. Dispenser with directional flow controlling flange and corresponding systems

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives

Also Published As

Publication number Publication date
BE877918A (fr) 1979-11-16
IE791496L (en) 1980-01-26
SE8001747L (sv) 1980-03-05
DK156716C (da) 1990-02-19
DK154211B (da) 1988-10-24
AU4920679A (en) 1980-01-31
DK154211C (da) 1989-03-13
DK156716B (da) 1989-09-25
CH650237A5 (de) 1985-07-15
US4188345A (en) 1980-02-12
JPS55500430A (fr) 1980-07-17
CH641445A5 (de) 1984-02-29
DK127580A (da) 1980-03-25
JPS55500428A (fr) 1980-07-17
JPS6312867B2 (fr) 1988-03-23
IE48463B1 (en) 1985-01-23
GB2026494B (en) 1982-12-15
FR2433514A1 (fr) 1980-03-14
GB2026494A (en) 1980-02-06
WO1980000339A1 (fr) 1980-03-06
NL7920012A (nl) 1980-05-30
IL57801A0 (en) 1979-11-30
DK127480A (da) 1980-03-25
FR2433514B1 (fr) 1986-05-23
WO1980000338A1 (fr) 1980-03-06
SE8001746L (sv) 1980-03-05
IL57801A (en) 1984-03-30
NZ190939A (en) 1982-09-07
JPS6312868B2 (fr) 1988-03-23
AU521131B2 (en) 1982-03-18

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