IL57801A - Fluorovitamin d compounds and their preparation - Google Patents

Fluorovitamin d compounds and their preparation

Info

Publication number
IL57801A
IL57801A IL57801A IL5780179A IL57801A IL 57801 A IL57801 A IL 57801A IL 57801 A IL57801 A IL 57801A IL 5780179 A IL5780179 A IL 5780179A IL 57801 A IL57801 A IL 57801A
Authority
IL
Israel
Prior art keywords
compounds
preparation
fluorovitamin
vitamin
fluorine
Prior art date
Application number
IL57801A
Other languages
English (en)
Other versions
IL57801A0 (en
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of IL57801A0 publication Critical patent/IL57801A0/xx
Priority to IL67448A priority Critical patent/IL67448A/xx
Publication of IL57801A publication Critical patent/IL57801A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL57801A 1978-07-26 1979-07-13 Fluorovitamin d compounds and their preparation IL57801A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL67448A IL67448A (en) 1978-07-26 1982-12-09 Preparation of fluoro-derivatives of vitamin d and certain novel 3,5-cyclovitamin d compounds used therein

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/928,279 US4188345A (en) 1978-07-26 1978-07-26 Fluorovitamin D compounds and processes for their preparation

Publications (2)

Publication Number Publication Date
IL57801A0 IL57801A0 (en) 1979-11-30
IL57801A true IL57801A (en) 1984-03-30

Family

ID=25456012

Family Applications (1)

Application Number Title Priority Date Filing Date
IL57801A IL57801A (en) 1978-07-26 1979-07-13 Fluorovitamin d compounds and their preparation

Country Status (14)

Country Link
US (1) US4188345A (xx)
JP (2) JPS6312867B2 (xx)
AU (1) AU521131B2 (xx)
BE (1) BE877918A (xx)
CH (2) CH650237A5 (xx)
DK (2) DK154211C (xx)
FR (1) FR2433514B1 (xx)
GB (1) GB2026494B (xx)
IE (1) IE48463B1 (xx)
IL (1) IL57801A (xx)
NL (2) NL7920016A (xx)
NZ (1) NZ190939A (xx)
SE (2) SE8001746L (xx)
WO (2) WO1980000338A1 (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196133A (en) * 1979-03-05 1980-04-01 Wisconsin Alumni Research Foundation 24,24-Difluoro-25-hydroxycholecalciferol
US4410515A (en) * 1981-04-01 1983-10-18 Massachusetts General Hospital Vitamin D glycosides and a method of use
WO1984000107A1 (en) * 1982-06-30 1984-01-19 Massachusetts Gen Hospital Vitamin d glycosides
US4428946A (en) * 1982-07-26 1984-01-31 Wisconsin Alumni Research Foundation Method of preventing milk fever in dairy cattle
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
FR2550789B1 (fr) * 1983-08-18 1987-12-04 Wisconsin Alumni Res Found 23,23-difluoro-25-hydroxy- et 1a,25-dihydroxy-vitamine d3
US4661294A (en) * 1985-03-18 1987-04-28 The General Hospital Corporation Biologically active 1-thio derivatives of vitamin D
US5401731A (en) * 1989-06-29 1995-03-28 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Productionsaktieselskab) Vitamin D analogues
TR25295A (tr) * 1992-02-26 1993-01-01 Simfer Dayanikli Tueketim Mamu Kati yakit yakan sobalar icin yanma havasi ön isitma sistemi
US5384314B1 (en) * 1994-03-11 1997-08-05 Hoffmann La Roche 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
WO1997011053A1 (en) * 1995-09-21 1997-03-27 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
JP2002505668A (ja) * 1997-05-16 2002-02-19 ウィメン アンド インファンツ ホスピタル 環状エーテルビタミンＤ３化合物、１α（ＯＨ）３−エピ−ビタミンＤ３化合物及びそれらの使用法
US7648973B2 (en) * 2006-04-06 2010-01-19 Wisconsin Alumni Research Foundation 2-methylene-1α,25-dihydroxy-19,21-dinorvitamin D3 analogs and uses thereof
US8404666B2 (en) 2006-04-06 2013-03-26 Wisconsin Alumni Research Foundation 2-substituted-1α,25-dihydroxy-19,26,27-trinor vitamin D analogs and uses thereof
CA2646909A1 (en) * 2006-04-06 2008-03-27 Hector F. Deluca 2-methylene-1alpha-hydroxy-19,21-dinorvitamin d3 analogs and uses thereof
MX2008012672A (es) * 2006-04-06 2008-10-15 Wisconsin Alumni Res Found Analogos de 2-metilen-1a-hidroxi-18,19,21-trinor vitamina d3 y sus usos.
WO2008125901A2 (en) * 2006-04-06 2008-10-23 Wisconsin Alumni Research Foundation 2-methylene-1alpha,25-dihydroxy-18,19,21-trinorvitamin d3 and uses thereof
US7538098B2 (en) * 2006-04-06 2009-05-26 Wisconsin Alumni Research Foundation 19-nor-vitamin D analogs with 1,2 or 3,2 heterocyclic ring
ATE496885T1 (de) * 2006-04-10 2011-02-15 Wisconsin Alumni Res Found 1-alpha-hydroxy-2-(3'-hydroxypropyliden)-19-nor vitamin-d-verbindungen mit einer 1,1- dimethylpropyl-seitenkette
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
US8814007B2 (en) 2010-12-31 2014-08-26 Medline Industries, Inc. Dispenser with directional flow controlling flange and corresponding systems

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives

Also Published As

Publication number Publication date
CH641445A5 (de) 1984-02-29
IE791496L (en) 1980-01-26
NL7920012A (nl) 1980-05-30
DK127580A (da) 1980-03-25
SE8001746L (sv) 1980-03-05
FR2433514B1 (fr) 1986-05-23
JPS55500428A (xx) 1980-07-17
WO1980000338A1 (en) 1980-03-06
JPS55500430A (xx) 1980-07-17
CH650237A5 (de) 1985-07-15
NL7920016A (nl) 1980-05-30
JPS6312867B2 (xx) 1988-03-23
AU521131B2 (en) 1982-03-18
NZ190939A (en) 1982-09-07
AU4920679A (en) 1980-01-31
SE8001747L (sv) 1980-03-05
DK156716C (da) 1990-02-19
IL57801A0 (en) 1979-11-30
FR2433514A1 (fr) 1980-03-14
JPS6312868B2 (xx) 1988-03-23
DK156716B (da) 1989-09-25
US4188345A (en) 1980-02-12
GB2026494B (en) 1982-12-15
WO1980000339A1 (en) 1980-03-06
IE48463B1 (en) 1985-01-23
BE877918A (fr) 1979-11-16
GB2026494A (en) 1980-02-06
DK154211B (da) 1988-10-24
DK154211C (da) 1989-03-13
DK127480A (da) 1980-03-25

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