DK156051C - Fremgangsmaade til separering af d-2-(6-methoxy-2-naphthyl)-propionsyre fra en blanding af d- og 1-2-(6-methoxy-2-naphthyl)-propionsyre - Google Patents

Fremgangsmaade til separering af d-2-(6-methoxy-2-naphthyl)-propionsyre fra en blanding af d- og 1-2-(6-methoxy-2-naphthyl)-propionsyre

Info

Publication number
DK156051C
DK156051C DK289080A DK289080A DK156051C DK 156051 C DK156051 C DK 156051C DK 289080 A DK289080 A DK 289080A DK 289080 A DK289080 A DK 289080A DK 156051 C DK156051 C DK 156051C
Authority
DK
Denmark
Prior art keywords
naphthyl
methoxy
propionic acid
separating
mixture
Prior art date
Application number
DK289080A
Other languages
Danish (da)
English (en)
Other versions
DK156051B (da
DK289080A (da
Inventor
Percy George Holton
Original Assignee
Syntex Pharma Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26734026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK156051(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/097,118 external-priority patent/US4246193A/en
Application filed by Syntex Pharma Int filed Critical Syntex Pharma Int
Publication of DK289080A publication Critical patent/DK289080A/da
Publication of DK156051B publication Critical patent/DK156051B/da
Application granted granted Critical
Publication of DK156051C publication Critical patent/DK156051C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/50—Use of additives, e.g. for stabilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK289080A 1979-07-06 1980-07-04 Fremgangsmaade til separering af d-2-(6-methoxy-2-naphthyl)-propionsyre fra en blanding af d- og 1-2-(6-methoxy-2-naphthyl)-propionsyre DK156051C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US5525879A 1979-07-06 1979-07-06
US5525879 1979-07-06
US06/097,118 US4246193A (en) 1979-11-26 1979-11-26 Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid
US9711879 1979-11-26

Publications (3)

Publication Number Publication Date
DK289080A DK289080A (da) 1981-01-07
DK156051B DK156051B (da) 1989-06-19
DK156051C true DK156051C (da) 1989-11-06

Family

ID=26734026

Family Applications (2)

Application Number Title Priority Date Filing Date
DK289080A DK156051C (da) 1979-07-06 1980-07-04 Fremgangsmaade til separering af d-2-(6-methoxy-2-naphthyl)-propionsyre fra en blanding af d- og 1-2-(6-methoxy-2-naphthyl)-propionsyre
DK239988A DK239988A (da) 1979-07-06 1988-05-03 Anvendelse af en blanding af d,1-2-(6-methoxy-2-naphthyl) propionsyre med en optisk aktiv base til fremstilling af d-2-(6-methoxy-2-naphtyl)-propionsyre

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK239988A DK239988A (da) 1979-07-06 1988-05-03 Anvendelse af en blanding af d,1-2-(6-methoxy-2-naphthyl) propionsyre med en optisk aktiv base til fremstilling af d-2-(6-methoxy-2-naphtyl)-propionsyre

Country Status (27)

Country Link
EP (1) EP0022529B1 (es)
JP (2) JPS63313749A (es)
KR (1) KR830000769B1 (es)
AR (1) AR225927A1 (es)
AU (1) AU544963B2 (es)
CA (1) CA1135717A (es)
CZ (1) CZ277725B6 (es)
DD (1) DD153367A5 (es)
DE (3) DE3051036C2 (es)
DK (2) DK156051C (es)
ES (1) ES493126A0 (es)
FR (2) FR2472557A1 (es)
GB (1) GB2054579B (es)
GR (1) GR68796B (es)
HK (1) HK886A (es)
IE (1) IE50000B1 (es)
IL (1) IL60498A (es)
IN (1) IN152737B (es)
IT (1) IT1130490B (es)
MY (1) MY8600452A (es)
NZ (1) NZ194237A (es)
PH (4) PH15674A (es)
PL (1) PL133439B1 (es)
PT (1) PT71486A (es)
RO (1) RO80655B (es)
SK (1) SK278340B6 (es)
YU (1) YU42673B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1168387B (it) * 1981-04-01 1987-05-20 Alfa Farmaceutici Spa Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico
ZA828453B (en) * 1981-12-08 1983-12-28 Boots Co Plc Therapeutic agents
IT1196197B (it) * 1984-07-23 1988-11-10 Ravizza Spa Procedimento per la risoluzione dell'acido (+)(-) 2-(2'-(p-fluorofenil)--5'-benzossazolil)-propionico
GB9121279D0 (en) * 1991-10-08 1991-11-20 Cerestar Holding Bv Process for the production of aminopolyols
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
KR100678287B1 (ko) * 2005-06-23 2007-02-02 한미약품 주식회사 클로피도그렐의 제조방법 및 이에 사용되는 중간체
KR101170537B1 (ko) * 2010-01-11 2012-08-01 김창운 해수의 자연순환이 가능한 내륙 내 바다양식 수조

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
DE1668654B2 (de) * 1967-01-13 1976-11-04 Syntex Corp., Panama 2-(6'-substituierte-2'-naphthyl)- propionsaeuren und -derivate, ihre herstellung und sie enthaltende arzneimittel
ZA70809B (en) * 1969-03-24 1971-09-29 Syntex Corp Amine salts of 2-(6'-methoxy-2'-naphthyl)propionic acids and processes for the preparation thereof
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids
US3904683A (en) * 1972-08-10 1975-09-09 Syntex Corp Process for the resolution of d- and 1-2-(6-methoxy-2-naphthyl) propionic acid
GR64816B (en) * 1977-03-08 1980-06-03 Boots Co Ltd Resolution of flurbiprofen ii/iii
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.

Also Published As

Publication number Publication date
IT8068053A0 (it) 1980-07-03
PL133439B1 (en) 1985-06-29
AU544963B2 (en) 1985-06-27
JPH0321535B2 (es) 1991-03-22
IN152737B (es) 1984-03-24
PT71486A (en) 1980-08-01
PH16432A (en) 1983-10-03
DE3025448C2 (es) 1987-05-21
IE50000B1 (en) 1986-01-22
RO80655A (ro) 1983-04-29
DD153367A5 (de) 1982-01-06
FR2472557B1 (es) 1984-04-20
CA1135717A (en) 1982-11-16
ES8105691A1 (es) 1981-06-16
KR830000769B1 (ko) 1983-04-11
FR2470108B1 (es) 1984-04-20
JPH0249749A (ja) 1990-02-20
IE801396L (en) 1981-01-06
AU6012180A (en) 1981-01-15
EP0022529B1 (en) 1983-06-29
MY8600452A (en) 1986-12-31
GB2054579A (en) 1981-02-18
DE3051036C2 (es) 1988-03-31
YU42673B (en) 1988-10-31
FR2472557A1 (fr) 1981-07-03
JPH0454B2 (es) 1992-01-06
IL60498A0 (en) 1980-09-16
DK239988D0 (da) 1988-05-03
PH16328A (en) 1983-09-05
NZ194237A (en) 1984-05-31
GR68796B (es) 1982-02-18
RO80655B (ro) 1983-04-30
PL225474A1 (es) 1981-03-27
DK239988A (da) 1988-05-03
DE3025448A1 (de) 1981-01-15
IT1130490B (it) 1986-06-11
FR2470108A1 (fr) 1981-05-29
CZ277725B6 (en) 1993-04-14
PH16431A (en) 1983-10-03
HK886A (en) 1986-01-10
IL60498A (en) 1984-06-29
DK156051B (da) 1989-06-19
AR225927A1 (es) 1982-05-14
CS477480A3 (en) 1992-11-18
GB2054579B (en) 1983-06-22
ES493126A0 (es) 1981-06-16
SK278340B6 (en) 1996-12-04
PH15674A (en) 1983-03-11
YU174380A (en) 1984-04-30
DK289080A (da) 1981-01-07
EP0022529A1 (en) 1981-01-21
JPS63313749A (ja) 1988-12-21
DE3063969D1 (en) 1983-08-04

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SU1279525A1 (ru) "cпocoб bыдeлehия -2-(6-metokcи-2-haфtил)-пpoпиohoboй kиcлotы или ee coлeй"

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