DK155915C - Fremgangsmaade til fremstilling af pertussis-toksoid til anvendelse i vacciner - Google Patents

Fremgangsmaade til fremstilling af pertussis-toksoid til anvendelse i vacciner

Info

Publication number
DK155915C
DK155915C DK009281A DK9281A DK155915C DK 155915 C DK155915 C DK 155915C DK 009281 A DK009281 A DK 009281A DK 9281 A DK9281 A DK 9281A DK 155915 C DK155915 C DK 155915C
Authority
DK
Denmark
Prior art keywords
vaccines
procedure
pertussis toxoid
preparing
preparing pertussis
Prior art date
Application number
DK009281A
Other languages
Danish (da)
English (en)
Other versions
DK9281A (da
DK155915B (da
Inventor
Yukio Syukuda
Hideo Watanabe
Shigeo Matsuyama
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DK9281A publication Critical patent/DK9281A/da
Publication of DK155915B publication Critical patent/DK155915B/da
Application granted granted Critical
Publication of DK155915C publication Critical patent/DK155915C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K2039/10Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
DK009281A 1980-09-12 1981-01-09 Fremgangsmaade til fremstilling af pertussis-toksoid til anvendelse i vacciner DK155915C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55127825A JPS5750925A (en) 1980-09-12 1980-09-12 Preparation of pertussis toxoid
JP12782580 1980-09-12

Publications (3)

Publication Number Publication Date
DK9281A DK9281A (da) 1982-03-13
DK155915B DK155915B (da) 1989-06-05
DK155915C true DK155915C (da) 1989-10-23

Family

ID=14969595

Family Applications (1)

Application Number Title Priority Date Filing Date
DK009281A DK155915C (da) 1980-09-12 1981-01-09 Fremgangsmaade til fremstilling af pertussis-toksoid til anvendelse i vacciner

Country Status (12)

Country Link
US (1) US4455297A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0047802B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5750925A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR840001512B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1152001A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3069433D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK155915C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES499112A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2083358A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU185404B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO159667C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU1297712A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59206316A (ja) * 1983-05-11 1984-11-22 Kaken Pharmaceut Co Ltd インシユリン分泌増強活性物質誘導体およびその製法
US4551429A (en) * 1983-09-15 1985-11-05 American Home Products Corporation Stimulation of antigen production by Bordetella pertussis
AU571078B2 (en) * 1984-04-14 1988-03-31 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Purification of filamentous hemagglutinin
GB8412207D0 (en) * 1984-05-12 1984-06-20 Wellcome Found Antigenic preparations
JPS60155127A (ja) * 1984-12-10 1985-08-15 Teijin Ltd 生物学的活性物質の製法
GB8512972D0 (en) * 1985-05-22 1985-06-26 Univ Glasgow Vaccine production
GB8601279D0 (en) * 1986-01-20 1986-02-26 Public Health Lab Service Purification of pertussis antigens
FR2597344B1 (fr) * 1986-04-16 1989-06-23 Merieux Inst Perfectionnement au procede de purification d'antigenes proteiques de bacteries appartenant au genre bordetella, en vue de l'obtention d'un vaccin acellulaire.
US4705686A (en) * 1986-05-09 1987-11-10 American Cyanamid Process for the preparation of acellular Bordetalla pertussis vaccine
US5032398A (en) * 1986-08-01 1991-07-16 Kaslow Harvey R Selective modification of the catalytic subunit of pertussis toxin
US5165927A (en) * 1986-08-01 1992-11-24 University Of Southern California Composition with modified pertussis toxin
CA1337859C (en) * 1987-04-24 1996-01-02 Masashi Chazono Method for culturing bordetella pertussis, a pertussis toxoid and a pertussis vaccine
US5139776A (en) * 1987-04-24 1992-08-18 The Research Foundation For Microbial Diseases Of Osaka University Method for culturing Bordetella pertussis, a pertussis toxoid and a pertussis vaccine
US5101019A (en) * 1987-05-22 1992-03-31 Takeda Chemical Industries, Ltd. Method for removing pertussis endotoxin, a pertussis toxoid and its production
JPS6485926A (en) * 1987-06-24 1989-03-30 Teijin Ltd Mutant of bordetella pertussis
GB8807860D0 (en) * 1988-04-05 1988-05-05 Connaught Lab Pertussis vaccine
JP2706792B2 (ja) * 1988-11-29 1998-01-28 財団法人化学及血清療法研究所 百日咳毒素のトキソイド化法
DK0396964T3 (da) * 1989-04-28 1995-10-30 Sclavo Spa Pertussistoxin-mutanter, Bordetella-stammer, der er i stand til at producere sådanne mutanter, samt deres anvendelse til udvikling af antipertussis-vacciner
GB8910570D0 (en) 1989-05-08 1989-06-21 Wellcome Found Acellular vaccine
CY1935A (en) * 1990-02-12 1991-02-07 Smithkline Beecham Biolog Novel vaccine and method therefor
US5578308A (en) * 1990-02-12 1996-11-26 Capiau; Carine Glutaraldehyde and formalin detoxified bordetella toxin vaccine
JPH0432188U (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1990-07-10 1992-03-16
US5616328A (en) * 1991-11-15 1997-04-01 Pfizer Inc. Method of preparing gram-negative bacterial vaccines
JP2634545B2 (ja) * 1992-10-27 1997-07-30 日本全薬工業株式会社 Rtxトキシンファミリーに属する細菌毒素ワクチンの製造法
US6051240A (en) * 1994-04-28 2000-04-18 Takeda Chemical Industries, Ltd. Method of separating protective components of Bordetella pertussis
RU2227746C1 (ru) * 2003-02-13 2004-04-27 Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова РАМН Способ получения анатоксина bordetella pertussis
BRPI0402630B8 (pt) * 2004-07-05 2021-05-25 Fund Butantan processo de obtenção de vacina pertussis celular menos reatogênica
RU2285540C2 (ru) * 2005-01-20 2006-10-20 Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова СПОСОБ ПОЛУЧЕНИЯ АНАТОКСИНА Bordetella pertussis
RU2332231C2 (ru) * 2006-07-31 2008-08-27 Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" Министерства здравоохранения Российской Федерации Способ получения бесклеточной вакцины для иммунопрофилактики коклюша
RU2504399C1 (ru) * 2012-12-06 2014-01-20 Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским и иммунопрофилактическим препаратам "Микроген" Министерства здравоохранения Российской Федерации (ФГУП "НПО "Микроген" Минздрава России) Способ получения бесклеточной вакцины для иммунопрофилактики коклюша

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB512196A (en) * 1937-08-19 1939-08-30 Lederle Lab Inc Method of preparing pertussis toxin and toxoid
US2359388A (en) * 1941-02-13 1944-10-03 Lederle Lab Inc Method of preparing pertussis toxin and toxoid
US3135662A (en) * 1961-01-05 1964-06-02 Burroughs Wellcome Co Diphtheria toxoid preparation and its production
NL6600706A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1965-02-05 1966-08-08
US4075321A (en) * 1973-05-04 1978-02-21 Agence Nationale De Valorisation De La Recherche (Anvar) Vaccines, the process for preparing the same and the applications thereof
DE2448530C3 (de) * 1974-10-11 1980-03-27 Behringwerke Ag, 3550 Marburg Verfahren zum Herstellen von Derivaten des Diphtherietoxins und diese enthaltende Mittel
DE2457047C3 (de) * 1974-12-03 1979-10-31 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Derivates der leichten Kette des Tetanustoxins, dessen Verwendung zur Tetanusprophylaxe
FR2393065A1 (fr) * 1977-05-31 1978-12-29 Merieux Inst Procede de separation de lipides d'endotoxines bacteriennes et notamment d'endotoxine de bordetella pertussis

Also Published As

Publication number Publication date
DE3069433D1 (en) 1984-11-15
KR840001512B1 (ko) 1984-09-29
EP0047802A2 (en) 1982-03-24
NO810014L (no) 1982-03-15
KR830004851A (ko) 1983-07-20
EP0047802A3 (en) 1982-12-29
GB2083358A (en) 1982-03-24
HU185404B (en) 1985-02-28
EP0047802B1 (en) 1984-10-10
CA1152001A (en) 1983-08-16
NO159667B (no) 1988-10-17
US4455297A (en) 1984-06-19
SU1297712A3 (ru) 1987-03-15
ES8202058A1 (es) 1982-02-01
JPS5750925A (en) 1982-03-25
DK9281A (da) 1982-03-13
JPS64928B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-01-10
NO159667C (no) 1989-02-01
DK155915B (da) 1989-06-05
ES499112A0 (es) 1982-02-01

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