DK155832C - Analogifremgangsmaade til fremstilling af n-acetyl--p-aminophenyl-n'-acetyl-alfa-amino-omega-methyl-thioalkansyreester - Google Patents

Analogifremgangsmaade til fremstilling af n-acetyl--p-aminophenyl-n'-acetyl-alfa-amino-omega-methyl-thioalkansyreester

Info

Publication number
DK155832C
DK155832C DK231578A DK231578A DK155832C DK 155832 C DK155832 C DK 155832C DK 231578 A DK231578 A DK 231578A DK 231578 A DK231578 A DK 231578A DK 155832 C DK155832 C DK 155832C
Authority
DK
Denmark
Prior art keywords
acetyl
thioalkane
alfa
aminophenyl
analogy
Prior art date
Application number
DK231578A
Other languages
English (en)
Other versions
DK155832B (da
DK231578A (da
Inventor
George Margetts
Roderic Stafford Andrews
Jean Legros
Original Assignee
Sterwin Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterwin Ag filed Critical Sterwin Ag
Publication of DK231578A publication Critical patent/DK231578A/da
Publication of DK155832B publication Critical patent/DK155832B/da
Application granted granted Critical
Publication of DK155832C publication Critical patent/DK155832C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK231578A 1977-05-26 1978-05-25 Analogifremgangsmaade til fremstilling af n-acetyl--p-aminophenyl-n'-acetyl-alfa-amino-omega-methyl-thioalkansyreester DK155832C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2221877 1977-05-26
GB22218/77A GB1583602A (en) 1977-05-26 1977-05-26 N-acetyl-para-aminophenyl-n'-acetyl-amino-thioalkanoic acid ester derivatives

Publications (3)

Publication Number Publication Date
DK231578A DK231578A (da) 1978-11-27
DK155832B DK155832B (da) 1989-05-22
DK155832C true DK155832C (da) 1989-10-02

Family

ID=10175844

Family Applications (1)

Application Number Title Priority Date Filing Date
DK231578A DK155832C (da) 1977-05-26 1978-05-25 Analogifremgangsmaade til fremstilling af n-acetyl--p-aminophenyl-n'-acetyl-alfa-amino-omega-methyl-thioalkansyreester

Country Status (15)

Country Link
US (4) US4181719A (da)
AT (1) AT368489B (da)
BE (1) BE867531A (da)
CH (1) CH644590A5 (da)
DE (1) DE2822789C2 (da)
DK (1) DK155832C (da)
FI (1) FI70208C (da)
FR (1) FR2391998A1 (da)
GB (1) GB1583602A (da)
IE (1) IE47072B1 (da)
IT (1) IT1202822B (da)
LU (1) LU79703A1 (da)
NL (1) NL176070C (da)
NO (1) NO146392C (da)
SE (1) SE448991B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1111384B (it) * 1978-12-21 1986-01-13 Sigma Tau Ind Farmaceuti Guaiacil esteri di derivati dello acido mercaptopropionico procedimento per la loro preparazione e loro uso terapeutico
US4307073A (en) * 1980-08-08 1981-12-22 The Research Foundation Of State University Of New York Method and composition for reducing the toxicity of acetaminophen
US4504413A (en) * 1982-04-02 1985-03-12 Syva Company Acetaminophen analogs, antigens, and antibodies
US5103021A (en) * 1982-04-02 1992-04-07 Syntex (U.S.A.) Inc. Acetaminophen analogs, antigens, and antibodies
US4605754A (en) * 1982-04-02 1986-08-12 Syntex (U.S.A.) Inc. Acetaminophen analogs
CH654302A5 (de) * 1983-05-04 1986-02-14 Sandoz Ag Acylaminophenolderivate, ihre herstellung und arzneimittel, welche sie enthalten.
GB9305058D0 (en) * 1993-03-12 1993-04-28 Penn Pharm Ltd Pharmaceutical compositions
DE19711053C2 (de) * 1997-03-03 1999-09-02 Rommelspacher Kombinationspräparat aus 2-Methyl-thiazolidin-2,4-dicarbonsäure und Paracetamol
FR2814366A1 (fr) * 2000-09-22 2002-03-29 Rhodia Chimie Sa Procede de granulation de matieres actives par extrusion basse pression pour l'obtention de granules directement compressibles
WO2002036077A2 (en) * 2000-11-06 2002-05-10 Andrx Pharmaceuticals, Inc. Once a day antihistamine and decongestant formulation
GB0114069D0 (en) * 2001-06-08 2001-08-01 Smithkline Beecham Plc Composition
US8092831B2 (en) * 2002-11-08 2012-01-10 Andrx Pharmaceuticals, Llc Antihistamine and decongestant system
AU2003291103A1 (en) * 2002-11-15 2004-06-15 Branded Products For The Future Pharmaceutical composition
US20050220862A1 (en) * 2004-03-31 2005-10-06 Bernstein Joel E Compositions with reduced hepatotoxicity
US20090298923A1 (en) * 2008-05-13 2009-12-03 Genmedica Therapeutics Sl Salicylate Conjugates Useful for Treating Metabolic Disorders
CA2724788C (en) * 2008-05-20 2016-12-06 Neurogesx, Inc. Hepatoprotectant acetaminophen mutual prodrugs
WO2010106083A1 (en) * 2009-03-16 2010-09-23 Genmedica Therapeutics Sl Combination therapies for treating metabolic disorders
WO2010106082A1 (en) * 2009-03-16 2010-09-23 Genmedica Therapeutics Sl Anti-inflammatory and antioxidant conjugates useful for treating metabolic disorders
US8466197B2 (en) 2010-12-14 2013-06-18 Genmedica Therapeutics Sl Thiocarbonates as anti-inflammatory and antioxidant compounds useful for treating metabolic disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR462M (da) * 1958-10-13 1961-05-02
US3591686A (en) * 1967-08-01 1971-07-06 Mead Johnson & Co Anti-inflammatory compositions and methods utilizing n-acylcysteines and the beta-alkyl and carboxyl derivatives thereof
US4038306A (en) * 1967-08-07 1977-07-26 Merck & Co., Inc. N-t-butoxycarbonyl-s-lower alkanoylamidomethyl-cysteine and p-nitrophenyl esters
GB1428803A (en) * 1973-05-29 1976-03-17 Gallardo Antonio Sa 4-acetamidophenyl esters of aryl-alkane carboxylic acids and a process for their preparation
US3983138A (en) * 1973-09-25 1976-09-28 Merck & Co., Inc. Amino acid esters
GB1463505A (en) * 1973-11-21 1977-02-02 Nat Res Dev Pharmaceutical compositions
US3996268A (en) * 1974-09-03 1976-12-07 The Regents Of The University Of California Cross-linking reagent for insulin synthesis

Also Published As

Publication number Publication date
IT7849547A0 (it) 1978-05-25
FR2391998A1 (fr) 1978-12-22
NO146392C (no) 1982-09-22
LU79703A1 (fr) 1978-11-06
DK155832B (da) 1989-05-22
SE448991B (sv) 1987-03-30
US4482495A (en) 1984-11-13
SE7806038L (sv) 1978-11-27
NO781824L (no) 1978-11-28
DE2822789C2 (de) 1984-01-12
US4405800A (en) 1983-09-20
US4361703A (en) 1982-11-30
FR2391998B1 (da) 1981-11-13
ATA380178A (de) 1982-02-15
DE2822789A1 (de) 1978-12-07
NL176070C (nl) 1985-02-18
IE47072B1 (en) 1983-12-14
IE781047L (en) 1978-11-26
US4181719A (en) 1980-01-01
GB1583602A (en) 1981-01-28
IT1202822B (it) 1989-02-09
NL176070B (nl) 1984-09-17
NL7805675A (nl) 1978-11-28
FI70208B (fi) 1986-02-28
CH644590A5 (de) 1984-08-15
FI781610A (fi) 1978-11-27
DK231578A (da) 1978-11-27
FI70208C (fi) 1986-09-15
BE867531A (fr) 1978-09-18
NO146392B (no) 1982-06-14
AT368489B (de) 1982-10-11

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