GB1428803A - 4-acetamidophenyl esters of aryl-alkane carboxylic acids and a process for their preparation - Google Patents

4-acetamidophenyl esters of aryl-alkane carboxylic acids and a process for their preparation

Info

Publication number
GB1428803A
GB1428803A GB2555173A GB2555173A GB1428803A GB 1428803 A GB1428803 A GB 1428803A GB 2555173 A GB2555173 A GB 2555173A GB 2555173 A GB2555173 A GB 2555173A GB 1428803 A GB1428803 A GB 1428803A
Authority
GB
United Kingdom
Prior art keywords
esters
carboxylic acids
acetamidophenyl
aryl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2555173A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antonio Gallardo SA
Original Assignee
Antonio Gallardo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antonio Gallardo SA filed Critical Antonio Gallardo SA
Priority to GB2555173A priority Critical patent/GB1428803A/en
Publication of GB1428803A publication Critical patent/GB1428803A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1428803 4-Acetamidophenol esters of aralkane carboxylic acids ANTONIO GALLARDO SA 22 July 1974 [29 May 1973] 25551/73 Heading C2C The invention comprises compounds of Formula (I) wherein R 1 is H, isobutyl, allyloxy or phenyl; R 2 is H, chlorine, benzoyl or α-hydroxybenzyl; and R 3 is H or methyl. They may be prepared by adding an acid halide of formula where X is a halogen atom, to a solution or suspension of 4-acetamidophenol, or a salt thereof, in an inert solvent. The compounds of Formula (I) are used as active ingredient in pharmaceutical compositions.
GB2555173A 1973-05-29 1973-05-29 4-acetamidophenyl esters of aryl-alkane carboxylic acids and a process for their preparation Expired GB1428803A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2555173A GB1428803A (en) 1973-05-29 1973-05-29 4-acetamidophenyl esters of aryl-alkane carboxylic acids and a process for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2555173A GB1428803A (en) 1973-05-29 1973-05-29 4-acetamidophenyl esters of aryl-alkane carboxylic acids and a process for their preparation

Publications (1)

Publication Number Publication Date
GB1428803A true GB1428803A (en) 1976-03-17

Family

ID=10229516

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2555173A Expired GB1428803A (en) 1973-05-29 1973-05-29 4-acetamidophenyl esters of aryl-alkane carboxylic acids and a process for their preparation

Country Status (1)

Country Link
GB (1) GB1428803A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2822789A1 (en) * 1977-05-26 1978-12-07 Sterwin Ag ANALGETIC COMPOUNDS, THE PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS WITH THESE ANALGETIC COMPOUNDS
FR2407913A1 (en) * 1977-11-03 1979-06-01 Sterwin Ag NEW ESTER OF ACETAMIDO-4 PHENOL WITH PHARMACOLOGICAL ACTIVITY, METHODS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT
WO1998027931A2 (en) * 1996-12-20 1998-07-02 Mcneil-Ppc, Inc. Salts of acetaminophen
US6160020A (en) * 1996-12-20 2000-12-12 Mcneill-Ppc, Inc. Alkali metal and alkaline-earth metal salts of acetaminophen
CN102863350A (en) * 2011-07-06 2013-01-09 中国科学院大连化学物理研究所 Anti-inflammatory analgesia mutual prodrug of non-steroidal antiinflammatory drug and preparation method thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2822789A1 (en) * 1977-05-26 1978-12-07 Sterwin Ag ANALGETIC COMPOUNDS, THE PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS WITH THESE ANALGETIC COMPOUNDS
FR2407913A1 (en) * 1977-11-03 1979-06-01 Sterwin Ag NEW ESTER OF ACETAMIDO-4 PHENOL WITH PHARMACOLOGICAL ACTIVITY, METHODS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT
WO1998027931A2 (en) * 1996-12-20 1998-07-02 Mcneil-Ppc, Inc. Salts of acetaminophen
WO1998027931A3 (en) * 1996-12-20 1998-10-01 Mcneil Ppc Inc Salts of acetaminophen
US6160020A (en) * 1996-12-20 2000-12-12 Mcneill-Ppc, Inc. Alkali metal and alkaline-earth metal salts of acetaminophen
CN102863350A (en) * 2011-07-06 2013-01-09 中国科学院大连化学物理研究所 Anti-inflammatory analgesia mutual prodrug of non-steroidal antiinflammatory drug and preparation method thereof
CN102863350B (en) * 2011-07-06 2015-06-17 中国科学院大连化学物理研究所 Anti-inflammatory analgesia mutual prodrug of non-steroidal antiinflammatory drug and preparation method thereof

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee