DK155322C - Fremgangsmaade til fremstilling af 14-hydroxymorphinan-derivater og farmaceutisk acceptable syreadditionssalte deraf samt mellemprodukt til anvendelse ved fremgangsmaaden - Google Patents
Fremgangsmaade til fremstilling af 14-hydroxymorphinan-derivater og farmaceutisk acceptable syreadditionssalte deraf samt mellemprodukt til anvendelse ved fremgangsmaadenInfo
- Publication number
- DK155322C DK155322C DK123877A DK123877A DK155322C DK 155322 C DK155322 C DK 155322C DK 123877 A DK123877 A DK 123877A DK 123877 A DK123877 A DK 123877A DK 155322 C DK155322 C DK 155322C
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- preparation
- acid addition
- addition salts
- acceptable acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/669,795 US4058531A (en) | 1976-03-23 | 1976-03-23 | Process for the preparation of 14-hydroxymorphinan derivatives |
US66979576 | 1976-03-23 | ||
US05/769,808 US4139534A (en) | 1977-02-17 | 1977-02-17 | Process for the preparation of 14-hydroxymorphinan derivatives |
US76980877 | 1977-02-17 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK123877A DK123877A (da) | 1977-09-24 |
DK155322B DK155322B (da) | 1989-03-28 |
DK155322C true DK155322C (da) | 1989-09-11 |
Family
ID=27100195
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK123877A DK155322C (da) | 1976-03-23 | 1977-03-21 | Fremgangsmaade til fremstilling af 14-hydroxymorphinan-derivater og farmaceutisk acceptable syreadditionssalte deraf samt mellemprodukt til anvendelse ved fremgangsmaaden |
DK597188A DK160987C (da) | 1976-03-23 | 1988-10-27 | 9,10-dihydroxy-perhydroisoquinolinderivater til anvendelse som mellemprodukt ved fremstilling af 14-hydroxy-morphinanderivater |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK597188A DK160987C (da) | 1976-03-23 | 1988-10-27 | 9,10-dihydroxy-perhydroisoquinolinderivater til anvendelse som mellemprodukt ved fremstilling af 14-hydroxy-morphinanderivater |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS52136176A (ja) |
CA (1) | CA1086723A (ja) |
CH (1) | CH629783A5 (ja) |
DK (2) | DK155322C (ja) |
FI (1) | FI61486C (ja) |
LU (1) | LU77000A1 (ja) |
NL (2) | NL189846C (ja) |
SE (1) | SE431749B (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0373510U (ja) * | 1989-11-15 | 1991-07-24 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3634429A (en) * | 1969-09-30 | 1972-01-11 | Hoffmann La Roche | Morphinan derivatives and preparation thereof |
CA919668A (en) * | 1970-06-20 | 1973-01-23 | Murakami Masuo | Morphinan derivatives |
BE788478A (fr) * | 1971-09-08 | 1973-03-06 | Bristol Myers Co | Procede de preparation de composes analgesiques |
US3775414A (en) * | 1972-05-10 | 1973-11-27 | Bristol Myers Co | Process for the preparation of 14-hydroxymorphinan derivatives |
-
1977
- 1977-03-17 JP JP2871277A patent/JPS52136176A/ja active Granted
- 1977-03-18 NL NLAANVRAGE7703000,A patent/NL189846C/xx active Protection Beyond IP Right Term
- 1977-03-18 CA CA274,241A patent/CA1086723A/en not_active Expired
- 1977-03-18 FI FI770865A patent/FI61486C/fi not_active IP Right Cessation
- 1977-03-21 DK DK123877A patent/DK155322C/da not_active IP Right Cessation
- 1977-03-21 SE SE7703236A patent/SE431749B/xx not_active IP Right Cessation
- 1977-03-22 CH CH358077A patent/CH629783A5/de not_active IP Right Cessation
- 1977-03-23 LU LU77000A patent/LU77000A1/xx unknown
-
1988
- 1988-10-27 DK DK597188A patent/DK160987C/da active
-
1996
- 1996-09-16 NL NL960022C patent/NL960022I1/nl unknown
Also Published As
Publication number | Publication date |
---|---|
JPS6139938B2 (ja) | 1986-09-06 |
NL189846B (nl) | 1993-03-16 |
NL7703000A (nl) | 1977-09-27 |
DK597188D0 (da) | 1988-10-27 |
SE7703236L (sv) | 1977-09-24 |
DK597188A (da) | 1988-10-27 |
FI61486B (fi) | 1982-04-30 |
DK123877A (da) | 1977-09-24 |
LU77000A1 (ja) | 1977-10-03 |
NL960022I1 (nl) | 1996-12-02 |
JPS52136176A (en) | 1977-11-14 |
DK160987B (da) | 1991-05-13 |
DK155322B (da) | 1989-03-28 |
FI770865A (ja) | 1977-09-24 |
CH629783A5 (en) | 1982-05-14 |
NL189846C (nl) | 1993-08-16 |
SE431749B (sv) | 1984-02-27 |
CA1086723A (en) | 1980-09-30 |
DK160987C (da) | 1991-11-11 |
FI61486C (fi) | 1982-08-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |