DK1551370T3 - Aggregat med foröget deformerbarhed, som omfatter mindst tre amfipater, til forbedret transport gennem semipermeable barrierer og til ikke-invasiv lægemiddeltilförsel in vivo, især gennem huden - Google Patents
Aggregat med foröget deformerbarhed, som omfatter mindst tre amfipater, til forbedret transport gennem semipermeable barrierer og til ikke-invasiv lægemiddeltilförsel in vivo, især gennem hudenInfo
- Publication number
- DK1551370T3 DK1551370T3 DK03757944T DK03757944T DK1551370T3 DK 1551370 T3 DK1551370 T3 DK 1551370T3 DK 03757944 T DK03757944 T DK 03757944T DK 03757944 T DK03757944 T DK 03757944T DK 1551370 T3 DK1551370 T3 DK 1551370T3
- Authority
- DK
- Denmark
- Prior art keywords
- application
- enhanced
- amphiphates
- aggregate
- vivo
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41784702P | 2002-10-11 | 2002-10-11 | |
| US10/357,618 US20040105881A1 (en) | 2002-10-11 | 2003-02-04 | Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin |
| US10/357,617 US7473432B2 (en) | 2002-10-11 | 2003-02-04 | NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery |
| PCT/EP2003/011202 WO2004032900A1 (en) | 2002-10-11 | 2003-10-09 | Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1551370T3 true DK1551370T3 (da) | 2008-03-03 |
Family
ID=32995875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03757944T DK1551370T3 (da) | 2002-10-11 | 2003-10-09 | Aggregat med foröget deformerbarhed, som omfatter mindst tre amfipater, til forbedret transport gennem semipermeable barrierer og til ikke-invasiv lægemiddeltilförsel in vivo, især gennem huden |
Country Status (22)
| Country | Link |
|---|---|
| EP (5) | EP1551370B1 (da) |
| JP (3) | JP2006505619A (da) |
| KR (1) | KR20050055723A (da) |
| CN (1) | CN1703199B (da) |
| AT (1) | ATE381316T1 (da) |
| AU (1) | AU2003273977B2 (da) |
| BR (1) | BR0315148A (da) |
| CA (1) | CA2498938A1 (da) |
| DE (1) | DE60318227T2 (da) |
| DK (1) | DK1551370T3 (da) |
| EA (1) | EA010407B1 (da) |
| ES (1) | ES2298566T3 (da) |
| HK (1) | HK1079113A1 (da) |
| HR (1) | HRPK20050421B3 (da) |
| IS (1) | IS7776A (da) |
| MX (1) | MXPA05003744A (da) |
| NO (1) | NO20052281L (da) |
| NZ (1) | NZ538571A (da) |
| PL (1) | PL377202A1 (da) |
| PT (1) | PT1551370E (da) |
| SI (1) | SI1551370T1 (da) |
| WO (1) | WO2004032900A1 (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2173679T3 (es) | 1999-01-27 | 2002-10-16 | Idea Ag | Inmunizacion/transporte transnasal con vehiculos altamente adaptables. |
| ES2173678T3 (es) | 1999-01-27 | 2002-10-16 | Idea Ag | Vacunacion no invasiva a traves de la piel. |
| CA2584475A1 (en) * | 2004-11-12 | 2006-05-18 | Idea Ag | Extended surface aggregates in the treatment of skin conditions |
| WO2009037061A2 (de) * | 2007-09-13 | 2009-03-26 | Basf Se | Verwendung von hydrophobin-polypeptiden als penetrationsverstärker |
| PL214538B1 (pl) * | 2009-05-28 | 2013-08-30 | P P F Hasco Lek Spolka Akcyjna | Kompozycja liposomowa zawierajaca naproksen i sposób wytwarzania kompozycji liposomowej zawierajacej naproksen |
| LT2437726T (lt) * | 2009-06-03 | 2018-09-10 | Sequessome Technology Holdings Limited | Kompozicijos, skirtos giliųjų audinių skausmo gydymui |
| NZ598906A (en) | 2009-08-21 | 2014-08-29 | Targeted Delivery Technologies Ltd | Vesicular formulations |
| EP2688554A2 (en) * | 2011-03-21 | 2014-01-29 | Gregor Cevc | Optimised preparations of highly adaptable aggregates |
| EP2712314A1 (en) * | 2011-03-21 | 2014-04-02 | Gregor Cevc | Drug-free compositions and methods for diminishing peripheral inflammation and pain |
| GB201205642D0 (en) | 2012-03-29 | 2012-05-16 | Sequessome Technology Holdings Ltd | Vesicular formulations |
| WO2014064444A1 (en) * | 2012-10-26 | 2014-05-01 | Oxford Nanopore Technologies Limited | Droplet interfaces |
| RU2524649C1 (ru) * | 2013-07-24 | 2014-07-27 | Станислав Анатольевич Кедик | Способ получения микросфер для приготовления инъецируемой лекарственной формы диклофенака, композиция и лекарственная форма |
| SG11201600424VA (en) * | 2013-07-31 | 2016-02-26 | Sequessome Technology Holdings Ltd | Vesicles |
| EP3049429B1 (en) * | 2013-09-26 | 2020-05-06 | National University of Singapore | Compositions and methods utilizing lysophosphatidylcholine scaffolds |
| CN105658782B (zh) * | 2013-10-25 | 2018-08-07 | 凸版印刷株式会社 | 膜囊泡回收设备、膜囊泡回收方法及膜囊泡分析方法 |
| LT3316857T (lt) | 2015-06-30 | 2021-11-25 | Sequessome Technology Holdings Limited | Daugiafazės kompozicijos |
| CN110662532A (zh) * | 2017-04-03 | 2020-01-07 | 加利福尼亚大学董事会 | 用于跨血脑屏障、透粘膜和经皮药物递送的可变形的纳米级媒介物(dnvs) |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| KR102149190B1 (ko) | 2018-04-09 | 2020-08-28 | 경상대학교산학협력단 | 액중 방전 마이크로젯 약물 전달장치 |
| JP2022529781A (ja) | 2019-04-17 | 2022-06-24 | コンパス パスファインダー リミテッド | サイロシビンによるうつ病及び他の様々な障害の治療 |
| MX2022014605A (es) | 2020-05-19 | 2022-12-16 | Cybin Irl Ltd | Derivados de triptamina deuterada y metodos de uso. |
| KR102209397B1 (ko) | 2020-07-21 | 2021-01-29 | 경상대학교산학협력단 | 액중 방전 마이크로젯 약물 전달장치 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6165500A (en) * | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
| CA2067754C (en) * | 1990-08-24 | 2002-06-04 | Gregor Cevc | Preparation for the application of agents in mini-droplets |
| DE4107153A1 (de) * | 1991-03-06 | 1992-09-10 | Gregor Cevc | Praeparat zur wirkstoffapplikation in kleinsttroepfchenform |
| DE4447287C1 (de) * | 1994-12-30 | 1996-11-07 | Cevc Gregor | Präparat zum Wirkstofftransport durch Barrieren |
| US20020048596A1 (en) * | 1994-12-30 | 2002-04-25 | Gregor Cevc | Preparation for the transport of an active substance across barriers |
| DE4447277A1 (de) * | 1994-12-30 | 1996-07-04 | Hoechst Ag | Stabilisierte, phosphormodifizierte Epoxidharze und ihre Verwendung |
| JP2002533379A (ja) * | 1998-12-23 | 2002-10-08 | イデア アクチェンゲゼルシャフト | 生体内における局所的に非侵襲性である用途のための改善された製剤 |
| ES2173679T3 (es) * | 1999-01-27 | 2002-10-16 | Idea Ag | Inmunizacion/transporte transnasal con vehiculos altamente adaptables. |
-
2003
- 2003-10-09 EP EP03757944A patent/EP1551370B1/en not_active Expired - Lifetime
- 2003-10-09 MX MXPA05003744A patent/MXPA05003744A/es active IP Right Grant
- 2003-10-09 EP EP06023465A patent/EP1815846A3/en not_active Withdrawn
- 2003-10-09 WO PCT/EP2003/011202 patent/WO2004032900A1/en active Application Filing
- 2003-10-09 PT PT03757944T patent/PT1551370E/pt unknown
- 2003-10-09 EA EA200500632A patent/EA010407B1/ru not_active IP Right Cessation
- 2003-10-09 ES ES03757944T patent/ES2298566T3/es not_active Expired - Lifetime
- 2003-10-09 EP EP06023468A patent/EP1815847A3/en not_active Withdrawn
- 2003-10-09 SI SI200331142T patent/SI1551370T1/sl unknown
- 2003-10-09 DK DK03757944T patent/DK1551370T3/da active
- 2003-10-09 AT AT03757944T patent/ATE381316T1/de active
- 2003-10-09 BR BR0315148-4A patent/BR0315148A/pt not_active IP Right Cessation
- 2003-10-09 CN CN2003801013013A patent/CN1703199B/zh not_active Expired - Fee Related
- 2003-10-09 CA CA002498938A patent/CA2498938A1/en not_active Abandoned
- 2003-10-09 EP EP06023467A patent/EP1829528A3/en not_active Withdrawn
- 2003-10-09 KR KR1020057004979A patent/KR20050055723A/ko not_active Application Discontinuation
- 2003-10-09 JP JP2005500984A patent/JP2006505619A/ja active Pending
- 2003-10-09 AU AU2003273977A patent/AU2003273977B2/en not_active Ceased
- 2003-10-09 EP EP06023466A patent/EP1829527A3/en not_active Withdrawn
- 2003-10-09 NZ NZ538571A patent/NZ538571A/en not_active IP Right Cessation
- 2003-10-09 DE DE60318227T patent/DE60318227T2/de not_active Expired - Lifetime
- 2003-10-09 PL PL377202A patent/PL377202A1/pl not_active Application Discontinuation
-
2005
- 2005-02-15 JP JP2005037992A patent/JP4555111B2/ja not_active Expired - Fee Related
- 2005-03-30 IS IS7776A patent/IS7776A/is unknown
- 2005-05-10 NO NO20052281A patent/NO20052281L/no not_active Application Discontinuation
- 2005-05-11 HR HR20050421A patent/HRPK20050421B3/xx not_active IP Right Cessation
- 2005-12-09 HK HK05111310A patent/HK1079113A1/xx not_active IP Right Cessation
-
2008
- 2008-11-04 JP JP2008283199A patent/JP2009108070A/ja active Pending
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