IS7776A - Þyrping með aukinn formbreytanleika, sem inniheldur minnst þrjú tvíleysin efni, til að bæta flutning gegnum hálfgegndræpa hindrun og til lyfjagjafar í lifandi líkama án inngrips, einkum gegnum húðina - Google Patents

Þyrping með aukinn formbreytanleika, sem inniheldur minnst þrjú tvíleysin efni, til að bæta flutning gegnum hálfgegndræpa hindrun og til lyfjagjafar í lifandi líkama án inngrips, einkum gegnum húðina

Info

Publication number
IS7776A
IS7776A IS7776A IS7776A IS7776A IS 7776 A IS7776 A IS 7776A IS 7776 A IS7776 A IS 7776A IS 7776 A IS7776 A IS 7776A IS 7776 A IS7776 A IS 7776A
Authority
IS
Iceland
Prior art keywords
application
clustering
skin
semi
live body
Prior art date
Application number
IS7776A
Other languages
English (en)
Inventor
Cevc Gregor
Vierl Ulrich
Original Assignee
Idea Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/357,617 external-priority patent/US7473432B2/en
Application filed by Idea Ag filed Critical Idea Ag
Publication of IS7776A publication Critical patent/IS7776A/is

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IS7776A 2002-10-11 2005-03-30 Þyrping með aukinn formbreytanleika, sem inniheldur minnst þrjú tvíleysin efni, til að bæta flutning gegnum hálfgegndræpa hindrun og til lyfjagjafar í lifandi líkama án inngrips, einkum gegnum húðina IS7776A (is)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US41784702P 2002-10-11 2002-10-11
US10/357,617 US7473432B2 (en) 2002-10-11 2003-02-04 NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery
US10/357,618 US20040105881A1 (en) 2002-10-11 2003-02-04 Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
PCT/EP2003/011202 WO2004032900A1 (en) 2002-10-11 2003-10-09 Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin

Publications (1)

Publication Number Publication Date
IS7776A true IS7776A (is) 2005-03-30

Family

ID=32995875

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7776A IS7776A (is) 2002-10-11 2005-03-30 Þyrping með aukinn formbreytanleika, sem inniheldur minnst þrjú tvíleysin efni, til að bæta flutning gegnum hálfgegndræpa hindrun og til lyfjagjafar í lifandi líkama án inngrips, einkum gegnum húðina

Country Status (22)

Country Link
EP (5) EP1815846A3 (is)
JP (3) JP2006505619A (is)
KR (1) KR20050055723A (is)
CN (1) CN1703199B (is)
AT (1) ATE381316T1 (is)
AU (1) AU2003273977B2 (is)
BR (1) BR0315148A (is)
CA (1) CA2498938A1 (is)
DE (1) DE60318227T2 (is)
DK (1) DK1551370T3 (is)
EA (1) EA010407B1 (is)
ES (1) ES2298566T3 (is)
HK (1) HK1079113A1 (is)
HR (1) HRPK20050421B3 (is)
IS (1) IS7776A (is)
MX (1) MXPA05003744A (is)
NO (1) NO20052281L (is)
NZ (1) NZ538571A (is)
PL (1) PL377202A1 (is)
PT (1) PT1551370E (is)
SI (1) SI1551370T1 (is)
WO (1) WO2004032900A1 (is)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1031347E (pt) 1999-01-27 2002-09-30 Idea Ag Transporte/imunizacao transnasal com veiculos muitissimo adaptaveis
ES2173678T3 (es) 1999-01-27 2002-10-16 Idea Ag Vacunacion no invasiva a traves de la piel.
EP1811961A2 (en) * 2004-11-12 2007-08-01 Idea Ag Extended surface aggregates in the treatment of skin conditions
CN101842118B (zh) * 2007-09-13 2012-08-08 巴斯夫欧洲公司 疏水蛋白多肽作为渗透增强剂的用途
PL214538B1 (pl) 2009-05-28 2013-08-30 P P F Hasco Lek Spolka Akcyjna Kompozycja liposomowa zawierajaca naproksen i sposób wytwarzania kompozycji liposomowej zawierajacej naproksen
MY170121A (en) * 2009-06-03 2019-07-05 Ulrich Vierl Formulations for the treatment of deep tissue pain
MX336482B (es) 2009-08-21 2016-01-21 Henk-Andre Kroon Formulaciones vesiculares.
US20140017302A1 (en) * 2011-03-21 2014-01-16 Gregor Cevc Optimised preparations of highly adaptable aggregates
EP2712314A1 (en) * 2011-03-21 2014-04-02 Gregor Cevc Drug-free compositions and methods for diminishing peripheral inflammation and pain
GB201205642D0 (en) 2012-03-29 2012-05-16 Sequessome Technology Holdings Ltd Vesicular formulations
AU2013336430B2 (en) * 2012-10-26 2018-02-15 Oxford Nanopore Technologies Limited Droplet interfaces
RU2524649C1 (ru) * 2013-07-24 2014-07-27 Станислав Анатольевич Кедик Способ получения микросфер для приготовления инъецируемой лекарственной формы диклофенака, композиция и лекарственная форма
CN105473162A (zh) * 2013-07-31 2016-04-06 斯昆申技术控股有限责任公司 囊泡
EP3049429B1 (en) * 2013-09-26 2020-05-06 National University of Singapore Compositions and methods utilizing lysophosphatidylcholine scaffolds
WO2015060446A1 (ja) * 2013-10-25 2015-04-30 凸版印刷株式会社 膜小胞回収デバイス、膜小胞回収方法、及び膜小胞分析方法
LT3316857T (lt) 2015-06-30 2021-11-25 Sequessome Technology Holdings Limited Daugiafazės kompozicijos
CA3058782A1 (en) * 2017-04-03 2018-10-11 The Regents Of The University Of California Deformable nano-scale vehicles (dnvs) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
KR102149190B1 (ko) 2018-04-09 2020-08-28 경상대학교산학협력단 액중 방전 마이크로젯 약물 전달장치
JP2022529781A (ja) 2019-04-17 2022-06-24 コンパス パスファインダー リミテッド サイロシビンによるうつ病及び他の様々な障害の治療
IL297492A (en) 2020-05-19 2022-12-01 Cybin Irl Ltd Denatured Tryptamine Derivatives and Methods of Use
KR102209397B1 (ko) 2020-07-21 2021-01-29 경상대학교산학협력단 액중 방전 마이크로젯 약물 전달장치

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4107153A1 (de) * 1991-03-06 1992-09-10 Gregor Cevc Praeparat zur wirkstoffapplikation in kleinsttroepfchenform
JP3765579B2 (ja) * 1990-08-24 2006-04-12 イーデーエーアー アーゲー 作用物質投与用超微小滴状調剤
US6165500A (en) * 1990-08-24 2000-12-26 Idea Ag Preparation for the application of agents in mini-droplets
DE4447287C1 (de) * 1994-12-30 1996-11-07 Cevc Gregor Präparat zum Wirkstofftransport durch Barrieren
DE4447277A1 (de) * 1994-12-30 1996-07-04 Hoechst Ag Stabilisierte, phosphormodifizierte Epoxidharze und ihre Verwendung
US20020048596A1 (en) * 1994-12-30 2002-04-25 Gregor Cevc Preparation for the transport of an active substance across barriers
BR9816113A (pt) * 1998-12-23 2001-10-23 Idea Ag Formulação aperfeiçoada para aplicação tópica não-invasiva in vivo
PT1031347E (pt) * 1999-01-27 2002-09-30 Idea Ag Transporte/imunizacao transnasal com veiculos muitissimo adaptaveis

Also Published As

Publication number Publication date
WO2004032900A8 (en) 2005-03-31
EA010407B1 (ru) 2008-08-29
AU2003273977A1 (en) 2004-05-04
CN1703199A (zh) 2005-11-30
DK1551370T3 (da) 2008-03-03
EP1829528A2 (en) 2007-09-05
EP1829527A3 (en) 2008-11-05
DE60318227D1 (de) 2008-01-31
EP1829527A2 (en) 2007-09-05
ATE381316T1 (de) 2008-01-15
KR20050055723A (ko) 2005-06-13
EP1551370A1 (en) 2005-07-13
HK1079113A1 (en) 2006-03-31
NZ538571A (en) 2007-05-31
SI1551370T1 (sl) 2008-06-30
EA200500632A1 (ru) 2005-12-29
DE60318227T2 (de) 2008-12-04
AU2003273977B2 (en) 2007-07-12
EP1815847A2 (en) 2007-08-08
HRP20050421A2 (en) 2005-12-31
EP1815846A3 (en) 2008-10-22
CA2498938A1 (en) 2004-04-22
NO20052281L (no) 2005-07-07
ES2298566T3 (es) 2008-05-16
JP2006505619A (ja) 2006-02-16
BR0315148A (pt) 2005-08-16
EP1829528A3 (en) 2008-11-05
PL377202A1 (pl) 2006-01-23
EP1815847A3 (en) 2008-11-05
MXPA05003744A (es) 2005-09-20
JP2005213261A (ja) 2005-08-11
HRPK20050421B3 (en) 2007-06-30
JP2009108070A (ja) 2009-05-21
EP1815846A2 (en) 2007-08-08
NO20052281D0 (no) 2005-05-10
CN1703199B (zh) 2010-04-28
WO2004032900A1 (en) 2004-04-22
EP1551370B1 (en) 2007-12-19
PT1551370E (pt) 2008-02-07
JP4555111B2 (ja) 2010-09-29

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