DK1543013T3 - 5-[[(2,3-Diflourphenyl)methyl]-7-[[2-hydroxymethyl)-1-methylethyl]amino]thiazolo(4,5-d]pyrimidin-2(3H)-on, mononatriumsalt som CXCR2-antagonist - Google Patents

5-[[(2,3-Diflourphenyl)methyl]-7-[[2-hydroxymethyl)-1-methylethyl]amino]thiazolo(4,5-d]pyrimidin-2(3H)-on, mononatriumsalt som CXCR2-antagonist

Info

Publication number
DK1543013T3
DK1543013T3 DK03748263T DK03748263T DK1543013T3 DK 1543013 T3 DK1543013 T3 DK 1543013T3 DK 03748263 T DK03748263 T DK 03748263T DK 03748263 T DK03748263 T DK 03748263T DK 1543013 T3 DK1543013 T3 DK 1543013T3
Authority
DK
Denmark
Prior art keywords
diflourphenyl
cxcr2
thiazolo
pyrimidin
methylethyl
Prior art date
Application number
DK03748263T
Other languages
Danish (da)
English (en)
Inventor
Roger Victor Bonnert
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1543013T3 publication Critical patent/DK1543013T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK03748263T 2002-09-20 2003-09-16 5-[[(2,3-Diflourphenyl)methyl]-7-[[2-hydroxymethyl)-1-methylethyl]amino]thiazolo(4,5-d]pyrimidin-2(3H)-on, mononatriumsalt som CXCR2-antagonist DK1543013T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0221828.7A GB0221828D0 (en) 2002-09-20 2002-09-20 Novel compound
PCT/GB2003/003998 WO2004026880A1 (en) 2002-09-20 2003-09-16 Novel compound

Publications (1)

Publication Number Publication Date
DK1543013T3 true DK1543013T3 (da) 2009-03-09

Family

ID=9944428

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03748263T DK1543013T3 (da) 2002-09-20 2003-09-16 5-[[(2,3-Diflourphenyl)methyl]-7-[[2-hydroxymethyl)-1-methylethyl]amino]thiazolo(4,5-d]pyrimidin-2(3H)-on, mononatriumsalt som CXCR2-antagonist

Country Status (27)

Country Link
US (2) US7585867B2 (ja)
EP (1) EP1543013B1 (ja)
JP (1) JP4619787B2 (ja)
KR (1) KR20050057427A (ja)
CN (1) CN1315848C (ja)
AR (1) AR041340A1 (ja)
AT (1) ATE419254T1 (ja)
AU (1) AU2003267571B2 (ja)
BR (1) BR0314844A (ja)
CA (1) CA2498762A1 (ja)
DE (1) DE60325614D1 (ja)
DK (1) DK1543013T3 (ja)
ES (1) ES2318152T3 (ja)
GB (1) GB0221828D0 (ja)
HK (1) HK1077060A1 (ja)
IS (1) IS7793A (ja)
MX (1) MXPA05002935A (ja)
NO (1) NO20051892L (ja)
NZ (1) NZ538826A (ja)
PL (1) PL375952A1 (ja)
PT (1) PT1543013E (ja)
RU (1) RU2342389C2 (ja)
SI (1) SI1543013T1 (ja)
TW (1) TW200413395A (ja)
UA (1) UA81257C2 (ja)
WO (1) WO2004026880A1 (ja)
ZA (1) ZA200502272B (ja)

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SE0003828D0 (sv) 2000-10-20 2000-10-20 Astrazeneca Ab Novel compounds
SE0102716D0 (sv) * 2001-08-14 2001-08-14 Astrazeneca Ab Novel compounds
GB0221828D0 (en) 2002-09-20 2002-10-30 Astrazeneca Ab Novel compound
GB0221829D0 (en) * 2002-09-20 2002-10-30 Astrazeneca Ab Novel compound
GB0328243D0 (en) 2003-12-05 2004-01-07 Astrazeneca Ab Methods
UA90707C2 (en) 2005-04-06 2010-05-25 Астразенека Аб Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives
AR053347A1 (es) 2005-04-06 2007-05-02 Astrazeneca Ab Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos
EP1912639A4 (en) * 2005-08-08 2011-10-12 Janssen Pharmaceutica Nv Thiazolopyrimidine KINASE INHIBITORS
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AR071036A1 (es) * 2008-03-26 2010-05-19 Astrazeneca Ab Derivados 5, 7-disustituidos de [1, 3]tiazolo[4, 5-d]pirimidin-2 (3h)-ona, una composicion farmaceutica que los comprende y su uso en el tratamiento de enfermedades mediadas por el receptor cx3cr1.
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Also Published As

Publication number Publication date
EP1543013A1 (en) 2005-06-22
WO2004026880A1 (en) 2004-04-01
AR041340A1 (es) 2005-05-11
JP2006503835A (ja) 2006-02-02
EP1543013B1 (en) 2008-12-31
AU2003267571A1 (en) 2004-04-08
SI1543013T1 (sl) 2009-04-30
AU2003267571B2 (en) 2007-08-16
ES2318152T3 (es) 2009-05-01
CN1681826A (zh) 2005-10-12
ZA200502272B (en) 2005-09-19
US20080306262A1 (en) 2008-12-11
IS7793A (is) 2005-04-11
BR0314844A (pt) 2005-08-09
RU2342389C2 (ru) 2008-12-27
US7585867B2 (en) 2009-09-08
TW200413395A (en) 2004-08-01
DE60325614D1 (de) 2009-02-12
HK1077060A1 (en) 2006-02-03
ATE419254T1 (de) 2009-01-15
NO20051892L (no) 2005-06-17
RU2005106356A (ru) 2005-11-20
UA81257C2 (en) 2007-12-25
MXPA05002935A (es) 2005-05-27
KR20050057427A (ko) 2005-06-16
CN1315848C (zh) 2007-05-16
US20060100221A1 (en) 2006-05-11
CA2498762A1 (en) 2004-04-01
JP4619787B2 (ja) 2011-01-26
PT1543013E (pt) 2009-02-27
NZ538826A (en) 2006-12-22
PL375952A1 (en) 2005-12-12
GB0221828D0 (en) 2002-10-30

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