DK1537132T3 - Salt af mortin-6-glucuronid - Google Patents

Salt af mortin-6-glucuronid

Info

Publication number
DK1537132T3
DK1537132T3 DK03787894T DK03787894T DK1537132T3 DK 1537132 T3 DK1537132 T3 DK 1537132T3 DK 03787894 T DK03787894 T DK 03787894T DK 03787894 T DK03787894 T DK 03787894T DK 1537132 T3 DK1537132 T3 DK 1537132T3
Authority
DK
Denmark
Prior art keywords
hbr
glucuronide
salt
mortin
medicament
Prior art date
Application number
DK03787894T
Other languages
Danish (da)
English (en)
Inventor
John Aitken Graham
Rudolf Franzmair
Original Assignee
Cenes Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cenes Ltd filed Critical Cenes Ltd
Application granted granted Critical
Publication of DK1537132T3 publication Critical patent/DK1537132T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK03787894T 2002-08-14 2003-08-14 Salt af mortin-6-glucuronid DK1537132T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0218811.8A GB0218811D0 (en) 2002-08-14 2002-08-14 Salts of morphine-6-glucuronide

Publications (1)

Publication Number Publication Date
DK1537132T3 true DK1537132T3 (da) 2006-05-08

Family

ID=9942230

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03787894T DK1537132T3 (da) 2002-08-14 2003-08-14 Salt af mortin-6-glucuronid

Country Status (17)

Country Link
US (1) US20060166900A1 (de)
EP (1) EP1537132B1 (de)
JP (1) JP4727990B2 (de)
KR (1) KR101077501B1 (de)
AT (1) ATE315041T1 (de)
AU (1) AU2003255790B2 (de)
CA (1) CA2494812C (de)
DE (1) DE60303149T2 (de)
DK (1) DK1537132T3 (de)
EA (1) EA008212B1 (de)
ES (1) ES2256790T3 (de)
GB (1) GB0218811D0 (de)
IL (1) IL166596A0 (de)
NO (1) NO20051261L (de)
PL (1) PL211031B1 (de)
WO (1) WO2004016633A1 (de)
ZA (1) ZA200501053B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007002597A2 (en) 2005-06-27 2007-01-04 Biovail Laboratories International S.R.L. Modified-release formulations of a bupropion salt
FR2939437B1 (fr) * 2008-12-10 2010-12-17 Sanofi Aventis Derives de morphine-6-glucuronide, leur preparation et leur application en therapeutique
FR2939796B1 (fr) * 2008-12-11 2010-12-17 Sanofi Aventis Derives bicycliques de morphine-6-glucuronide, leur preparation et leur application en therapeutique
CN107028968B (zh) * 2016-02-03 2020-12-04 江苏恒瑞医药股份有限公司 一种含有葡萄糖醛酸吗啡或其可药用盐的药物组合物
US20180110939A1 (en) 2016-10-21 2018-04-26 Somniferum Labs LLC Method, system and apparatus for controlled delivery of opioid and other medications
CN110054656B (zh) * 2019-05-28 2021-02-02 宜昌人福药业有限责任公司 一种10-羰基/羟基吗啡-6-葡萄糖苷酸的合成方法
CN113831373B (zh) * 2020-06-23 2023-05-16 宜昌人福药业有限责任公司 一种吗啡-6-葡萄糖苷酸脱水物杂质的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908389A (en) * 1986-08-27 1990-03-13 Warner-Lambert Company Penetration enhancement system
FR2680786B1 (fr) * 1991-09-04 1995-03-10 Irepa Procede de synthese de glucuronides d'epoxy-4,5 morphinanes.
DE4403709A1 (de) * 1994-02-07 1995-08-10 Lohmann Therapie Syst Lts Pharmazeutische Zusammensetzung zur systemischen transdermalen Verabreichung mit dem Wirkstoff Morphin-6-glucuronid
US5460826A (en) * 1994-06-27 1995-10-24 Alza Corporation Morphine therapy
JPH10513485A (ja) * 1995-11-29 1998-12-22 ロラボ エセ エレ オピエート性物質の糖結合体
ID26296A (id) * 1997-09-25 2000-12-14 Lohmann Therapie Syst Lts Garam penambahan asam dari alkaloid morfin dan penggunaannya
US6740641B2 (en) * 2001-07-27 2004-05-25 Euro-Celtique, S.A. Sugar derivatives of hydromorphone, dihydromorphine and dihydromorphine, compositions thereof and uses for treating or preventing pain

Also Published As

Publication number Publication date
IL166596A0 (en) 2006-01-15
ES2256790T3 (es) 2006-07-16
JP4727990B2 (ja) 2011-07-20
EP1537132B1 (de) 2006-01-04
EA200500175A1 (ru) 2005-08-25
US20060166900A1 (en) 2006-07-27
GB0218811D0 (en) 2002-09-18
WO2004016633A1 (en) 2004-02-26
JP2006500360A (ja) 2006-01-05
PL373553A1 (en) 2005-09-05
NO20051261L (no) 2005-03-11
CA2494812C (en) 2011-03-08
PL211031B1 (pl) 2012-04-30
AU2003255790A1 (en) 2004-03-03
EA008212B1 (ru) 2007-04-27
ZA200501053B (en) 2005-10-26
CA2494812A1 (en) 2004-02-26
EP1537132A1 (de) 2005-06-08
AU2003255790B2 (en) 2010-05-27
DE60303149T2 (de) 2006-09-28
KR20050055710A (ko) 2005-06-13
KR101077501B1 (ko) 2011-10-28
ATE315041T1 (de) 2006-02-15
DE60303149D1 (de) 2006-03-30

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