DK1537132T3 - Salt af mortin-6-glucuronid - Google Patents

Salt af mortin-6-glucuronid

Info

Publication number
DK1537132T3
DK1537132T3 DK03787894T DK03787894T DK1537132T3 DK 1537132 T3 DK1537132 T3 DK 1537132T3 DK 03787894 T DK03787894 T DK 03787894T DK 03787894 T DK03787894 T DK 03787894T DK 1537132 T3 DK1537132 T3 DK 1537132T3
Authority
DK
Denmark
Prior art keywords
hbr
glucuronide
salt
mortin
medicament
Prior art date
Application number
DK03787894T
Other languages
Danish (da)
English (en)
Inventor
John Aitken Graham
Rudolf Franzmair
Original Assignee
Cenes Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cenes Ltd filed Critical Cenes Ltd
Application granted granted Critical
Publication of DK1537132T3 publication Critical patent/DK1537132T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK03787894T 2002-08-14 2003-08-14 Salt af mortin-6-glucuronid DK1537132T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0218811.8A GB0218811D0 (en) 2002-08-14 2002-08-14 Salts of morphine-6-glucuronide

Publications (1)

Publication Number Publication Date
DK1537132T3 true DK1537132T3 (da) 2006-05-08

Family

ID=9942230

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03787894T DK1537132T3 (da) 2002-08-14 2003-08-14 Salt af mortin-6-glucuronid

Country Status (17)

Country Link
US (1) US20060166900A1 (de)
EP (1) EP1537132B1 (de)
JP (1) JP4727990B2 (de)
KR (1) KR101077501B1 (de)
AT (1) ATE315041T1 (de)
AU (1) AU2003255790B2 (de)
CA (1) CA2494812C (de)
DE (1) DE60303149T2 (de)
DK (1) DK1537132T3 (de)
EA (1) EA008212B1 (de)
ES (1) ES2256790T3 (de)
GB (1) GB0218811D0 (de)
IL (1) IL166596A0 (de)
NO (1) NO20051261L (de)
PL (1) PL211031B1 (de)
WO (1) WO2004016633A1 (de)
ZA (1) ZA200501053B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1896002A4 (de) 2005-06-27 2009-11-25 Biovail Lab Int Srl Bupropionsalzformulierungen mit modifizierter freisetzung
FR2939437B1 (fr) * 2008-12-10 2010-12-17 Sanofi Aventis Derives de morphine-6-glucuronide, leur preparation et leur application en therapeutique
FR2939796B1 (fr) * 2008-12-11 2010-12-17 Sanofi Aventis Derives bicycliques de morphine-6-glucuronide, leur preparation et leur application en therapeutique
CN107028968B (zh) * 2016-02-03 2020-12-04 江苏恒瑞医药股份有限公司 一种含有葡萄糖醛酸吗啡或其可药用盐的药物组合物
US20180110725A1 (en) 2016-10-21 2018-04-26 Somniferum Labs LLC Compositions, methods and kits for the safe inhaled delivery of targeted opioids for the treatment of pain and addiction
CN110054656B (zh) * 2019-05-28 2021-02-02 宜昌人福药业有限责任公司 一种10-羰基/羟基吗啡-6-葡萄糖苷酸的合成方法
CN113831373B (zh) * 2020-06-23 2023-05-16 宜昌人福药业有限责任公司 一种吗啡-6-葡萄糖苷酸脱水物杂质的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908389A (en) * 1986-08-27 1990-03-13 Warner-Lambert Company Penetration enhancement system
FR2680786B1 (fr) * 1991-09-04 1995-03-10 Irepa Procede de synthese de glucuronides d'epoxy-4,5 morphinanes.
DE4403709A1 (de) * 1994-02-07 1995-08-10 Lohmann Therapie Syst Lts Pharmazeutische Zusammensetzung zur systemischen transdermalen Verabreichung mit dem Wirkstoff Morphin-6-glucuronid
US5460826A (en) * 1994-06-27 1995-10-24 Alza Corporation Morphine therapy
WO1997021416A2 (es) * 1995-11-29 1997-06-19 Rolabo Sl Glicoconjugados de substancias opiaceas
SK4322000A3 (en) * 1997-09-25 2000-10-09 Lohmann Therapie Syst Lts Transdermal or transmucosal composition for administering morphine alkaloids, the application thereof, appropriate compounds and method for their producing
US6740641B2 (en) * 2001-07-27 2004-05-25 Euro-Celtique, S.A. Sugar derivatives of hydromorphone, dihydromorphine and dihydromorphine, compositions thereof and uses for treating or preventing pain

Also Published As

Publication number Publication date
AU2003255790B2 (en) 2010-05-27
CA2494812A1 (en) 2004-02-26
IL166596A0 (en) 2006-01-15
EA200500175A1 (ru) 2005-08-25
ZA200501053B (en) 2005-10-26
NO20051261L (no) 2005-03-11
AU2003255790A1 (en) 2004-03-03
JP2006500360A (ja) 2006-01-05
EP1537132A1 (de) 2005-06-08
GB0218811D0 (en) 2002-09-18
DE60303149T2 (de) 2006-09-28
ATE315041T1 (de) 2006-02-15
CA2494812C (en) 2011-03-08
US20060166900A1 (en) 2006-07-27
PL211031B1 (pl) 2012-04-30
JP4727990B2 (ja) 2011-07-20
DE60303149D1 (de) 2006-03-30
WO2004016633A1 (en) 2004-02-26
KR101077501B1 (ko) 2011-10-28
KR20050055710A (ko) 2005-06-13
EA008212B1 (ru) 2007-04-27
PL373553A1 (en) 2005-09-05
ES2256790T3 (es) 2006-07-16
EP1537132B1 (de) 2006-01-04

Similar Documents

Publication Publication Date Title
NO20062504L (no) Sammensetninger og doseringsformer for forbedret absorpsjon
DE602004024375D1 (de) Carboxamidderivate
TW200716628A (en) Novel compounds
UY27720A1 (es) Aroilpiridinonas monocíclicas,
SE0300010D0 (sv) Novel Compounds
SE0401342D0 (sv) Therapeutic compounds
CY1116554T1 (el) Αλατα κλοπιδογρελης και μεθοδος παρασκευης
CY1111470T1 (el) Νεες φαρμακευτικες συνθεσεις που περιεχουν φλιβανσερινη πολυμορφη α
SE9900961D0 (sv) Novel compounds
SE0401345D0 (sv) Therapeutic compounds: Pyridine as scaffold
DE60322412D1 (de) Pharmazeutische feste Dispersionen von Modafinil-Verbindungen
NO20051261L (no) Morfin-6-glukuronidsalt
ATE287267T1 (de) Kombinationstherapien mit gefässschädigender aktivität
DE60142913D1 (de) Arzneilösungen enthaltend modafinilverbindungen
SE9802208D0 (sv) Novel compounds
EA200501821A1 (ru) Фармацевтическая комбинация, содержащая модафинил и другой лекарственный препарат
BR0210912A (pt) Compostos e composições como inibidores de catepsina
SE9802209D0 (sv) Novel compounds
SE0300457D0 (sv) Novel compounds
SE0000303D0 (sv) Novel compounds
ITMI20030972A1 (it) Indazolo dotato di attivita' analgesica, metodo per prepararlo e composizione farmaceutica che lo comprende.
GB0326221D0 (en) Therapeutic agents,compositions,preparations and uses
EP1591123A4 (de) Verwendung von naringenin, naringin und salzen daraus als schleimlöser bei der behandlung von husten sowie zusammensetzungen daraus
MXPA05012117A (es) Derivados de diarilmetiliden piperidina, preparaciones de los mismos y usos de los mismos.
BRPI0410020A (pt) composto e/ou um seu sal ou estereoisÈmero farmaceuticamente aceitável, processo para preparar e uso do mesmo, composição farmacêutica, e, kit farmacêutico