DK151624C - Analogifremgangsmaade til fremstilling af et 1-ethyl-6,8-difluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)quinolinderivat eller farmaceutisk acceptable salte deraf. - Google Patents
Analogifremgangsmaade til fremstilling af et 1-ethyl-6,8-difluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)quinolinderivat eller farmaceutisk acceptable salte deraf.Info
- Publication number
- DK151624C DK151624C DK098582A DK98582A DK151624C DK 151624 C DK151624 C DK 151624C DK 098582 A DK098582 A DK 098582A DK 98582 A DK98582 A DK 98582A DK 151624 C DK151624 C DK 151624C
- Authority
- DK
- Denmark
- Prior art keywords
- difluor
- piperazinyl
- dihydro
- oxo
- ethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3227481 | 1981-03-06 | ||
| JP56032274A JPS57145862A (en) | 1981-03-06 | 1981-03-06 | Quinolinecarboxylic acid derivative |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK98582A DK98582A (da) | 1982-09-07 |
| DK151624B DK151624B (da) | 1987-12-21 |
| DK151624C true DK151624C (da) | 1988-06-27 |
Family
ID=12354397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK098582A DK151624C (da) | 1981-03-06 | 1982-03-05 | Analogifremgangsmaade til fremstilling af et 1-ethyl-6,8-difluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)quinolinderivat eller farmaceutisk acceptable salte deraf. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4429127A (xx) |
| JP (1) | JPS57145862A (xx) |
| KR (1) | KR880000689B1 (xx) |
| AR (1) | AR228085A1 (xx) |
| AT (1) | AT382146B (xx) |
| AU (1) | AU544761B2 (xx) |
| BE (1) | BE892388A (xx) |
| CA (1) | CA1215986A (xx) |
| CH (1) | CH649290A5 (xx) |
| DE (1) | DE3205655A1 (xx) |
| DK (1) | DK151624C (xx) |
| ES (1) | ES8306484A1 (xx) |
| FR (1) | FR2501204B1 (xx) |
| GB (1) | GB2094305B (xx) |
| HU (1) | HU187449B (xx) |
| IN (1) | IN155968B (xx) |
| IT (1) | IT1150198B (xx) |
| MX (1) | MX167628B (xx) |
| NL (1) | NL192618C (xx) |
| PH (1) | PH17166A (xx) |
| SE (1) | SE446984B (xx) |
| ZA (1) | ZA821027B (xx) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4665079A (en) * | 1984-02-17 | 1987-05-12 | Warner-Lambert Company | Antibacterial agents |
| JPS59155381A (ja) * | 1983-02-22 | 1984-09-04 | Kyorin Pharmaceut Co Ltd | ベンゾキノリジンカルボン酸誘導体及びその製造法 |
| DE3308908A1 (de) * | 1983-03-12 | 1984-09-13 | Bayer Ag, 5090 Leverkusen | Bakterizide mittel |
| DE3318145A1 (de) * | 1983-05-18 | 1984-11-22 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| NZ208470A (en) * | 1983-07-18 | 1988-06-30 | Abbott Lab | 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such |
| US4730000A (en) * | 1984-04-09 | 1988-03-08 | Abbott Laboratories | Quinoline antibacterial compounds |
| AU553415B2 (en) * | 1983-09-19 | 1986-07-17 | Abbott Japan Co., Ltd. | 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids |
| EP0154780B1 (en) * | 1984-01-26 | 1990-04-11 | Abbott Laboratories | Quinoline antibacterial compounds |
| US4774246A (en) * | 1984-01-26 | 1988-09-27 | Abbott Laboratories | Quinoline antibacterial compounds |
| DE3409922A1 (de) * | 1984-03-17 | 1985-09-26 | Bayer Ag, 5090 Leverkusen | 1,7-diamino-1,4-dihydro-4-oxo-3-(aza)chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung bakterieller erkrankungen |
| EP0184384B1 (en) * | 1984-12-06 | 1989-08-02 | Pfizer Inc. | Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them |
| US4851535A (en) * | 1985-01-23 | 1989-07-25 | Toyama Chemical Co., Ltd. | Nicotinic acid derivatives |
| US4755513A (en) * | 1985-01-30 | 1988-07-05 | Otsuka Pharmaceutical Company, Limited | Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds |
| DE3504643A1 (de) * | 1985-02-12 | 1986-08-14 | Bayer Ag, 5090 Leverkusen | 1-cyclopropyl-1,4-dihydro-4-oxo-7-(4-(2-oxo-1,3-dioxol-4-yl-methyl)-1-piperazinyl)-3-chinolin carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| US4689325A (en) * | 1985-12-23 | 1987-08-25 | Abbott Laboratories | Isoxazolo-pyrido-phenoxazine and isothiazolo-pyrido-phenoxazine derivatives |
| US4687770A (en) * | 1985-12-23 | 1987-08-18 | Abbott Laboratories | Isoxazolo-pyrido-benzoxazine and isothiazolo-pyrido-benzoxazine derivatives |
| US4940710A (en) * | 1986-01-17 | 1990-07-10 | American Cyanamid Company | 7-(substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids |
| US4692454A (en) * | 1986-02-03 | 1987-09-08 | Warner-Lambert Company | Opthalmic use of quinolone antibiotics |
| CA2114981A1 (en) | 1993-02-09 | 1994-08-10 | Kazumi Ogata | Quinolonecarboxylic acid derivatives |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5312889A (en) | 1976-07-22 | 1978-02-04 | Dainippon Pharmaceut Co Ltd | P-aminobenzylpiperazine dervatives |
| JPS53141286A (en) * | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
| CA1175836A (en) | 1977-09-20 | 1984-10-09 | Marcel Pesson | Production of 1,4-dihydroquinoline-3-carboxylic acid derivatives |
| JPS5845426B2 (ja) * | 1978-09-29 | 1983-10-08 | 杏林製薬株式会社 | 置換キノリンカルボン酸誘導体 |
| GB2030562B (en) * | 1978-10-04 | 1982-10-27 | Kyorin Seiyaku Kk | Substituted quinolinecarboxylic acid |
| JPS5653656A (en) | 1979-10-05 | 1981-05-13 | Tanabe Seiyaku Co Ltd | Quinoline derivative and its preparation |
-
1981
- 1981-03-06 JP JP56032274A patent/JPS57145862A/ja active Granted
-
1982
- 1982-02-12 AU AU80451/82A patent/AU544761B2/en not_active Expired
- 1982-02-16 NL NL8200582A patent/NL192618C/nl not_active IP Right Cessation
- 1982-02-17 DE DE19823205655 patent/DE3205655A1/de active Granted
- 1982-02-17 ZA ZA821027A patent/ZA821027B/xx unknown
- 1982-02-17 US US06/349,660 patent/US4429127A/en not_active Expired - Lifetime
- 1982-02-24 IT IT19831/82A patent/IT1150198B/it active
- 1982-03-01 MX MX013592A patent/MX167628B/es unknown
- 1982-03-02 IN IN242/CAL/82A patent/IN155968B/en unknown
- 1982-03-03 PH PH26938-AA patent/PH17166A/en unknown
- 1982-03-04 CH CH1335/82A patent/CH649290A5/de not_active IP Right Cessation
- 1982-03-04 GB GB8206376A patent/GB2094305B/en not_active Expired
- 1982-03-04 FR FR8203594A patent/FR2501204B1/fr not_active Expired
- 1982-03-05 DK DK098582A patent/DK151624C/da not_active IP Right Cessation
- 1982-03-05 KR KR8200951A patent/KR880000689B1/ko active
- 1982-03-05 HU HU82687A patent/HU187449B/hu unknown
- 1982-03-05 CA CA000397700A patent/CA1215986A/en not_active Expired
- 1982-03-05 BE BE0/207490A patent/BE892388A/fr not_active IP Right Cessation
- 1982-03-05 AR AR286639A patent/AR228085A1/es active
- 1982-03-05 SE SE8201386A patent/SE446984B/sv not_active IP Right Cessation
- 1982-03-05 ES ES510163A patent/ES8306484A1/es not_active Expired
- 1982-03-08 AT AT0089982A patent/AT382146B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL8200582A (nl) | 1982-10-01 |
| IN155968B (xx) | 1985-04-13 |
| JPS57145862A (en) | 1982-09-09 |
| CA1215986A (en) | 1986-12-30 |
| FR2501204A1 (fr) | 1982-09-10 |
| MX167628B (es) | 1993-03-31 |
| SE8201386L (sv) | 1982-09-07 |
| ES510163A0 (es) | 1983-06-01 |
| KR830009084A (ko) | 1983-12-17 |
| AU8045182A (en) | 1982-09-09 |
| FR2501204B1 (fr) | 1986-03-28 |
| HU187449B (en) | 1986-01-28 |
| DE3205655A1 (de) | 1982-09-23 |
| DE3205655C2 (xx) | 1988-12-08 |
| ATA89982A (de) | 1986-06-15 |
| AU544761B2 (en) | 1985-06-13 |
| ZA821027B (en) | 1983-01-26 |
| ES8306484A1 (es) | 1983-06-01 |
| PH17166A (en) | 1984-06-13 |
| IT1150198B (it) | 1986-12-10 |
| US4429127A (en) | 1984-01-31 |
| GB2094305B (en) | 1984-08-01 |
| JPH0145468B2 (xx) | 1989-10-03 |
| BE892388A (fr) | 1982-09-06 |
| SE446984B (sv) | 1986-10-20 |
| KR880000689B1 (ko) | 1988-04-23 |
| AR228085A1 (es) | 1983-01-14 |
| CH649290A5 (de) | 1985-05-15 |
| DK151624B (da) | 1987-12-21 |
| NL192618C (nl) | 1997-11-04 |
| IT8219831A0 (it) | 1982-02-24 |
| AT382146B (de) | 1987-01-12 |
| NL192618B (nl) | 1997-07-01 |
| DK98582A (da) | 1982-09-07 |
| GB2094305A (en) | 1982-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |