DK149599C - Fremgangsmaade til fremstilling af aminosukkerderivater kaldet trestatina, trestatin b og trestatin c eller salte deraf - Google Patents

Fremgangsmaade til fremstilling af aminosukkerderivater kaldet trestatina, trestatin b og trestatin c eller salte deraf

Info

Publication number
DK149599C
DK149599C DK61179A DK61179A DK149599C DK 149599 C DK149599 C DK 149599C DK 61179 A DK61179 A DK 61179A DK 61179 A DK61179 A DK 61179A DK 149599 C DK149599 C DK 149599C
Authority
DK
Denmark
Prior art keywords
trestatin
trestatina
salts
procedure
preparation
Prior art date
Application number
DK61179A
Other languages
Danish (da)
English (en)
Other versions
DK149599B (da
DK61179A (da
Inventor
Yasuji Suhara
Kiyoshi Ogawa
Kazuteru Yokose
Kimihiro Watanabe
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK61179A publication Critical patent/DK61179A/da
Publication of DK149599B publication Critical patent/DK149599B/da
Application granted granted Critical
Publication of DK149599C publication Critical patent/DK149599C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99Enzyme inactivation by chemical treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK61179A 1978-02-14 1979-02-13 Fremgangsmaade til fremstilling af aminosukkerderivater kaldet trestatina, trestatin b og trestatin c eller salte deraf DK149599C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB583478 1978-02-14
GB583478 1978-02-14

Publications (3)

Publication Number Publication Date
DK61179A DK61179A (da) 1979-08-15
DK149599B DK149599B (da) 1986-08-04
DK149599C true DK149599C (da) 1987-06-01

Family

ID=9803510

Family Applications (1)

Application Number Title Priority Date Filing Date
DK61179A DK149599C (da) 1978-02-14 1979-02-13 Fremgangsmaade til fremstilling af aminosukkerderivater kaldet trestatina, trestatin b og trestatin c eller salte deraf

Country Status (26)

Country Link
US (1) US4273765A (OSRAM)
EP (1) EP0003616B1 (OSRAM)
JP (1) JPS54163511A (OSRAM)
AR (1) AR219150A1 (OSRAM)
AT (1) AT367451B (OSRAM)
AU (1) AU527318B2 (OSRAM)
CA (1) CA1121290A (OSRAM)
DE (2) DE2905649A1 (OSRAM)
DK (1) DK149599C (OSRAM)
ES (1) ES477653A1 (OSRAM)
FI (1) FI63062C (OSRAM)
FR (1) FR2416901A1 (OSRAM)
GR (1) GR72817B (OSRAM)
HU (1) HU181442B (OSRAM)
IE (1) IE47916B1 (OSRAM)
IL (1) IL56626A0 (OSRAM)
LU (1) LU80906A1 (OSRAM)
MC (1) MC1253A1 (OSRAM)
NL (1) NL7901182A (OSRAM)
NO (1) NO153011C (OSRAM)
NZ (1) NZ189625A (OSRAM)
PH (1) PH15084A (OSRAM)
PT (1) PT69218A (OSRAM)
SE (1) SE7901276L (OSRAM)
YU (1) YU41437B (OSRAM)
ZA (1) ZA79528B (OSRAM)

Families Citing this family (37)

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DE3166093D1 (en) * 1981-01-05 1984-10-18 Takeda Chemical Industries Ltd N-substituted pseudo-aminosugars, their production and use
JPS57146713A (en) * 1981-03-09 1982-09-10 Akira Endo Hypoglycemic
US4595678A (en) * 1982-03-19 1986-06-17 Takeda Chemical Industries, Ltd. N-substituted pseudo-aminosugars and pharmaceutical compositions containing same
US4678812A (en) * 1986-05-30 1987-07-07 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4762857A (en) * 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4885361A (en) * 1987-07-31 1989-12-05 Hoffmann-La Roche Inc. Sulfated oligosaccharides
ATE132269T1 (de) * 1990-11-30 1996-01-15 Monoclonetics Int Verfahren zur diagnose chronischer niedriger rückenschmerzen und nackenschmerzen
TW381025B (en) * 1993-08-05 2000-02-01 Hoffmann La Roche Pharmaceutical composition containing a glucosidase inhibitor and a lipase inhibitor
EP1157696B1 (en) * 2000-05-24 2006-10-25 Pfizer Limited Treatment of rumen acidosis with alpha-amylase inhibitors
US7022684B2 (en) * 2000-05-24 2006-04-04 Pfizer Inc. Treatment of rumen acidosis with α-amylase inhibitors
JP2007512359A (ja) 2003-11-19 2007-05-17 メタバシス・セラピューティクス・インコーポレイテッド 新規なリン含有甲状腺ホルモン様物質
US7262318B2 (en) * 2004-03-10 2007-08-28 Pfizer, Inc. Substituted heteroaryl- and phenylsulfamoyl compounds
US20050288340A1 (en) * 2004-06-29 2005-12-29 Pfizer Inc Substituted heteroaryl- and phenylsulfamoyl compounds
DE602005016009D1 (de) * 2004-11-23 2009-09-24 Warner Lambert Co 7-(2h-pyrazol-3-yl)-3,5-dihydroxy-heptansäure-derivate als hmg-co-a-reductase-inhibitoren zur behandlung von lipidemia
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
ATE547394T1 (de) 2006-12-01 2012-03-15 Bristol Myers Squibb Co N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CN103601792B (zh) 2007-06-04 2016-06-29 协同医药品公司 有效用于胃肠功能紊乱、炎症、癌症和其他疾病治疗的鸟苷酸环化酶激动剂
CN101998998A (zh) 2008-04-11 2011-03-30 安斯泰来制药株式会社 氨基糖化合物及其生产方法
AU2009256157B2 (en) 2008-06-04 2014-12-18 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
WO2010093601A1 (en) 2009-02-10 2010-08-19 Metabasis Therapeutics, Inc. Novel sulfonic acid-containing thyromimetics, and methods for their use
JP2013528172A (ja) 2010-05-21 2013-07-08 ファイザー・インク 2−フェニルベンゾイルアミド
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2828343A1 (en) 2011-03-04 2012-09-13 The Scripps Research Institute Edn3-like peptides and uses thereof
MY188344A (en) 2012-03-09 2021-12-01 Biotropics Malaysia Berhad Extract formulations of rhodamnia cinerea and uses thereof
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2909442A1 (en) 2013-04-17 2014-10-23 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
EP4424697A3 (en) 2013-06-05 2024-12-25 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase c, method of making and using same
JP6769963B2 (ja) 2014-08-29 2020-10-14 ティエエッセ ファルマ ソチエタ レスポンサビリタ リミタータ α−アミノ−β−カルボキシムコン酸セミアルデヒド脱炭酸酵素の阻害剤
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
AU2017342083A1 (en) 2016-10-14 2019-04-11 Tes Pharma S.R.L. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
CA3119509A1 (en) 2018-11-20 2020-05-28 Tes Pharma S.R.L Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxxylase
EP4470609A3 (en) 2019-01-18 2025-03-12 Astrazeneca AB Pcsk9 inhibitors and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2064092C2 (de) * 1970-12-28 1983-06-01 Bayer Ag, 5090 Leverkusen Inhibitoren für Glykosidhydrolasen aus Actinomyceten
US4062950A (en) * 1973-09-22 1977-12-13 Bayer Aktiengesellschaft Amino sugar derivatives
DE2347782C3 (de) * 1973-09-22 1979-10-11 Bayer Ag, 5090 Leverkusen Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US4065557A (en) * 1974-03-21 1977-12-27 Bayer Aktiengesellschaft Amino sugars and their use in improving the meat:fat ratio in animals
USRE29903E (en) 1975-03-19 1979-02-06 American Cyanamid Company Antibacterial antibiotics AM31α, AM31β and AM31γ
DE2614393C3 (de) * 1976-04-02 1980-04-03 Bayer Ag, 5090 Leverkusen Aminozucker-Derivate und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
IE790274L (en) 1979-08-14
FI63062B (fi) 1982-12-31
HU181442B (en) 1983-07-28
FR2416901A1 (fr) 1979-09-07
NL7901182A (nl) 1979-08-16
PH15084A (en) 1982-07-02
FI63062C (fi) 1983-04-11
CA1121290A (en) 1982-04-06
NO153011C (no) 1986-01-02
NO153011B (no) 1985-09-23
AU4402879A (en) 1979-08-23
LU80906A1 (de) 1980-09-24
YU34879A (en) 1983-01-21
IL56626A0 (en) 1979-05-31
NO790469L (no) 1979-08-15
FI790486A7 (fi) 1979-08-15
EP0003616A2 (de) 1979-08-22
FR2416901B1 (OSRAM) 1980-10-24
DK149599B (da) 1986-08-04
JPS54163511A (en) 1979-12-26
GR72817B (OSRAM) 1983-12-06
EP0003616B1 (de) 1982-02-24
YU41437B (en) 1987-06-30
AT367451B (de) 1982-07-12
NZ189625A (en) 1981-05-01
DE2962165D1 (en) 1982-03-25
JPS643877B2 (OSRAM) 1989-01-23
IE47916B1 (en) 1984-07-25
SE7901276L (sv) 1979-08-15
AU527318B2 (en) 1983-02-24
MC1253A1 (fr) 1980-01-14
DK61179A (da) 1979-08-15
DE2905649A1 (de) 1979-08-16
ZA79528B (en) 1980-02-27
ATA108879A (de) 1981-11-15
EP0003616A3 (en) 1979-09-05
PT69218A (en) 1979-03-01
AR219150A1 (es) 1980-07-31
US4273765A (en) 1981-06-16
ES477653A1 (es) 1980-03-01

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