NO153011C - Fremgangsmaate ved fremstilling av trestatin a, b og c. - Google Patents

Fremgangsmaate ved fremstilling av trestatin a, b og c.

Info

Publication number
NO153011C
NO153011C NO790469A NO790469A NO153011C NO 153011 C NO153011 C NO 153011C NO 790469 A NO790469 A NO 790469A NO 790469 A NO790469 A NO 790469A NO 153011 C NO153011 C NO 153011C
Authority
NO
Norway
Prior art keywords
trestatin
procedure
preparation
Prior art date
Application number
NO790469A
Other languages
English (en)
Norwegian (no)
Other versions
NO790469L (no
NO153011B (no
Inventor
Yasuji Suhara
Kiyoshi Ogawa
Kazuteru Yokose
Kimihiro Watanabe
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO790469L publication Critical patent/NO790469L/no
Publication of NO153011B publication Critical patent/NO153011B/no
Publication of NO153011C publication Critical patent/NO153011C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99—Enzyme inactivation by chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO790469A 1978-02-14 1979-02-13 Fremgangsmaate ved fremstilling av trestatin a, b og c. NO153011C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB583478 1978-02-14

Publications (3)

Publication Number Publication Date
NO790469L NO790469L (no) 1979-08-15
NO153011B NO153011B (no) 1985-09-23
NO153011C true NO153011C (no) 1986-01-02

Family

ID=9803510

Family Applications (1)

Application Number Title Priority Date Filing Date
NO790469A NO153011C (no) 1978-02-14 1979-02-13 Fremgangsmaate ved fremstilling av trestatin a, b og c.

Country Status (26)

Country Link
US (1) US4273765A (OSRAM)
EP (1) EP0003616B1 (OSRAM)
JP (1) JPS54163511A (OSRAM)
AR (1) AR219150A1 (OSRAM)
AT (1) AT367451B (OSRAM)
AU (1) AU527318B2 (OSRAM)
CA (1) CA1121290A (OSRAM)
DE (2) DE2905649A1 (OSRAM)
DK (1) DK149599C (OSRAM)
ES (1) ES477653A1 (OSRAM)
FI (1) FI63062C (OSRAM)
FR (1) FR2416901A1 (OSRAM)
GR (1) GR72817B (OSRAM)
HU (1) HU181442B (OSRAM)
IE (1) IE47916B1 (OSRAM)
IL (1) IL56626A0 (OSRAM)
LU (1) LU80906A1 (OSRAM)
MC (1) MC1253A1 (OSRAM)
NL (1) NL7901182A (OSRAM)
NO (1) NO153011C (OSRAM)
NZ (1) NZ189625A (OSRAM)
PH (1) PH15084A (OSRAM)
PT (1) PT69218A (OSRAM)
SE (1) SE7901276L (OSRAM)
YU (1) YU41437B (OSRAM)
ZA (1) ZA79528B (OSRAM)

Families Citing this family (37)

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EP0056194B1 (en) 1981-01-05 1984-09-12 Takeda Chemical Industries, Ltd. N-substituted pseudo-aminosugars, their production and use
JPS57146713A (en) * 1981-03-09 1982-09-10 Akira Endo Hypoglycemic
US4595678A (en) * 1982-03-19 1986-06-17 Takeda Chemical Industries, Ltd. N-substituted pseudo-aminosugars and pharmaceutical compositions containing same
US4678812A (en) * 1986-05-30 1987-07-07 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4762857A (en) * 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4885361A (en) * 1987-07-31 1989-12-05 Hoffmann-La Roche Inc. Sulfated oligosaccharides
AU667462B2 (en) * 1990-11-30 1996-03-28 Monoclonetics International Incorporated Methods for the diagnosis of chronic lower back and cervical pain
CA2128044C (en) * 1993-08-05 2007-02-20 Klaus-Dieter Bremer Pharmaceutical compositions comprising a glucosidase and/or amylase inhibitor, and a lipase inhibitor
IL186223A0 (en) * 2000-05-24 2008-01-20 Pfizer Treatment of rumen acidosis with ??-amylase inhibitors
US7022684B2 (en) * 2000-05-24 2006-04-04 Pfizer Inc. Treatment of rumen acidosis with α-amylase inhibitors
EP1689383B1 (en) 2003-11-19 2012-10-31 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
US7262318B2 (en) * 2004-03-10 2007-08-28 Pfizer, Inc. Substituted heteroaryl- and phenylsulfamoyl compounds
US20050288340A1 (en) * 2004-06-29 2005-12-29 Pfizer Inc Substituted heteroaryl- and phenylsulfamoyl compounds
MX2007005137A (es) * 2004-11-23 2007-06-22 Warner Lambert Co Derivados del acido 7-(2h-pyrazol-3-il)-3, 5-dihidroxi-heptanoico como inhibidores de hmg co-a reductasa para el tratamiento de lipidemia.
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
ATE547394T1 (de) 2006-12-01 2012-03-15 Bristol Myers Squibb Co N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen
ES2559319T3 (es) 2007-06-04 2016-02-11 Synergy Pharmaceuticals Inc. Agonistas de guanilato cliclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2264179A1 (en) 2008-04-11 2010-12-22 Astellas Pharma Inc. Aminosugar compound and process for production thereof
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2010009319A2 (en) 2008-07-16 2010-01-21 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US20120046364A1 (en) 2009-02-10 2012-02-23 Metabasis Therapeutics, Inc. Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
US20130072519A1 (en) 2010-05-21 2013-03-21 Edward Lee Conn 2-phenyl benzoylamides
WO2012027331A1 (en) 2010-08-27 2012-03-01 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EP2680874A2 (en) 2011-03-04 2014-01-08 Pfizer Inc Edn3-like peptides and uses thereof
MY188344A (en) 2012-03-09 2021-12-01 Biotropics Malaysia Berhad Extract formulations of rhodamnia cinerea and uses thereof
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのｎ−ピペリジン−３−イルベンズアミド誘導体
WO2014197720A2 (en) 2013-06-05 2014-12-11 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase c, method of making and using same
KR102431436B1 (ko) 2014-08-29 2022-08-10 테스 파마 에스.알.엘. α-아미노-β-카복시뮤콘산 세미알데히드 데카복실라제의 억제제
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
EP3526199B1 (en) 2016-10-14 2022-04-13 Tes Pharma S.r.l. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
AU2019385644B2 (en) 2018-11-20 2025-10-30 Tes Pharma S.R.L. Inhibitors of α-Amino-β-carboxymuconic acid semialdehyde decarboxylase
HRP20241674T1 (hr) 2019-01-18 2025-02-14 Astrazeneca Ab 6'-[[(1s,3s)-3-[[5-(difluormetoksi)-2-pirimidinil]amino]ciklopentil]amino][1(2h),3'-bipiridin]-2-on kao inhibitor pcsk9 i postupci njegove upotrebe

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2064092C2 (de) * 1970-12-28 1983-06-01 Bayer Ag, 5090 Leverkusen Inhibitoren für Glykosidhydrolasen aus Actinomyceten
US4062950A (en) * 1973-09-22 1977-12-13 Bayer Aktiengesellschaft Amino sugar derivatives
DE2347782C3 (de) * 1973-09-22 1979-10-11 Bayer Ag, 5090 Leverkusen Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US4065557A (en) * 1974-03-21 1977-12-27 Bayer Aktiengesellschaft Amino sugars and their use in improving the meat:fat ratio in animals
USRE29903E (en) 1975-03-19 1979-02-06 American Cyanamid Company Antibacterial antibiotics AM31α, AM31β and AM31γ
DE2614393C3 (de) * 1976-04-02 1980-04-03 Bayer Ag, 5090 Leverkusen Aminozucker-Derivate und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
MC1253A1 (fr) 1980-01-14
PH15084A (en) 1982-07-02
DK61179A (da) 1979-08-15
JPS54163511A (en) 1979-12-26
FI63062C (fi) 1983-04-11
US4273765A (en) 1981-06-16
DK149599B (da) 1986-08-04
FR2416901B1 (OSRAM) 1980-10-24
DK149599C (da) 1987-06-01
ZA79528B (en) 1980-02-27
AU4402879A (en) 1979-08-23
EP0003616A2 (de) 1979-08-22
ES477653A1 (es) 1980-03-01
HU181442B (en) 1983-07-28
YU41437B (en) 1987-06-30
IL56626A0 (en) 1979-05-31
NL7901182A (nl) 1979-08-16
NZ189625A (en) 1981-05-01
EP0003616B1 (de) 1982-02-24
AT367451B (de) 1982-07-12
EP0003616A3 (en) 1979-09-05
SE7901276L (sv) 1979-08-15
NO790469L (no) 1979-08-15
IE47916B1 (en) 1984-07-25
FI790486A7 (fi) 1979-08-15
PT69218A (en) 1979-03-01
IE790274L (en) 1979-08-14
ATA108879A (de) 1981-11-15
FR2416901A1 (fr) 1979-09-07
AR219150A1 (es) 1980-07-31
LU80906A1 (de) 1980-09-24
DE2962165D1 (en) 1982-03-25
YU34879A (en) 1983-01-21
GR72817B (OSRAM) 1983-12-06
CA1121290A (en) 1982-04-06
JPS643877B2 (OSRAM) 1989-01-23
NO153011B (no) 1985-09-23
DE2905649A1 (de) 1979-08-16
AU527318B2 (en) 1983-02-24
FI63062B (fi) 1982-12-31

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